NCAM1/FGF module serves as a putative pleuropulmonary blastoma therapeutic target

[1]  V. Berezin,et al.  Correction: The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking , 2019, The Journal of cell biology.

[2]  M. Zamai,et al.  Number and brightness analysis reveals that NCAM and FGF2 elicit different assembly and dynamics of FGFR1 in live cells , 2019, Journal of Cell Science.

[3]  T. Kalisky,et al.  In Vivo Expansion of Cancer Stemness Affords Novel Cancer Stem Cell Targets: Malignant Rhabdoid Tumor as an Example , 2018, Stem cell reports.

[4]  A. Nagler,et al.  PPARG is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target , 2017, EMBO molecular medicine.

[5]  Y. Kakeji,et al.  NCAM- and FGF-2-mediated FGFR1 signaling in the tumor microenvironment of esophageal cancer regulates the survival and migration of tumor-associated macrophages and cancer cells. , 2016, Cancer letters.

[6]  R. Friesel,et al.  Sef Regulates Epithelial‐Mesenchymal Transition in Breast Cancer Cells , 2016, Journal of cellular biochemistry.

[7]  Gretchen M. Williams,et al.  Pleuropulmonary Blastoma: Evolution of an Entity as an Entry into a Familial Tumor Predisposition Syndrome , 2015, Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.

[8]  Y. Takada,et al.  Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells , 2015, PloS one.

[9]  M. Kamenova,et al.  Diagnosis and treatment of pleuropulmonary blastoma—single center experience , 2015, Pediatric pulmonology.

[10]  N. Magné,et al.  [FGF/FGFR signalling: Implication in oncogenesis and perspectives]. , 2015, Bulletin du cancer.

[11]  N. Magné,et al.  [FGF/FGFR signalling: Implication in oncogenesis and perspectives]. , 2015, Bulletin du cancer.

[12]  Ashley D. Hill,et al.  Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links DICER1 Loss to the Pathogenesis of Pleuropulmonary Blastoma , 2015, PLoS genetics.

[13]  Gretchen M. Williams,et al.  Pleuropulmonary blastoma: A report on 350 central pathology–confirmed pleuropulmonary blastoma cases by the International Pleuropulmonary Blastoma Registry , 2015, Cancer.

[14]  K. Takata,et al.  Primary Cutaneous NK/T-cell Lymphoma, Nasal Type and CD56-positive Peripheral T-cell Lymphoma: A Cellular Lineage and Clinicopathologic Study of 60 Patients From Asia , 2015, The American journal of surgical pathology.

[15]  T. Tan,et al.  The clinical role of epithelial-mesenchymal transition and stem cell markers in advanced-stage ovarian serous carcinoma effusions. , 2015, Human pathology.

[16]  N. Komatsu,et al.  CD56-positive adult T-cell leukemia/lymphoma: a case report and a review of the literature , 2015, Medical Molecular Morphology.

[17]  Eyal Peer,et al.  Wilms’ Tumor Blastemal Stem Cells Dedifferentiate to Propagate the Tumor Bulk , 2014, Stem cell reports.

[18]  Gretchen M. Williams,et al.  DICER1-Related Disorders , 2014 .

[19]  Gretchen M. Williams,et al.  DICER1-Pleuropulmonary Blastoma Familial Tumor Predisposition Syndrome: A Unique Constellation of Neoplastic Conditions , 2014, Pathology case reviews.

[20]  R. Lutz,et al.  Lorvotuzumab mertansine, a CD56-targeting antibody-drug conjugate with potent antitumor activity against small cell lung cancer in human xenograft models , 2014, mAbs.

[21]  R. Shukrun,et al.  Targeted therapy aimed at cancer stem cells: Wilms’ tumor as an example , 2014, Pediatric Nephrology.

[22]  E. Fridman,et al.  The isolation and characterization of renal cancer initiating cells from human Wilms' tumour xenografts unveils new therapeutic targets† , 2012, EMBO molecular medicine.

[23]  H. Erickson,et al.  ADME of Antibody–Maytansinoid Conjugates , 2012, The AAPS Journal.

[24]  M. Tenhagen,et al.  Fibroblast growth factor receptors in breast cancer: expression, downstream effects, and possible drug targets. , 2012, Endocrine-related cancer.

[25]  I. Ahmad,et al.  Mechanisms of FGFR-mediated carcinogenesis. , 2012, Biochimica et biophysica acta.

[26]  M. Tenhagen.  FGFRs in breast cancer: expression, downstream effects and possible drug targets , 2012 .

[27]  V. Berezin,et al.  The adhesion molecule NCAM promotes ovarian cancer progression via FGFR signalling , 2011, EMBO molecular medicine.

[28]  B. Dekel,et al.  Wilms tumor—a renal stem cell malignancy? , 2011, Pediatric Nephrology.

[29]  R. S. Goldstein,et al.  Resistance or sensitivity of Wilms’ tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target , 2011, Oncogene.

[30]  N. Turner,et al.  Fibroblast growth factor signalling: from development to cancer , 2010, Nature Reviews Cancer.

[31]  Ario de Marco,et al.  The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking , 2009, The Journal of cell biology.

[32]  N. Amariglio,et al.  Developmental tumourigenesis: NCAM as a putative marker for the malignant renal stem/progenitor cell population , 2009, Journal of cellular and molecular medicine.

[33]  M. Dishop,et al.  Primary and metastatic lung tumors in the pediatric population: a review and 25-year experience at a large children's hospital. , 2009, Archives of pathology & laboratory medicine.

[34]  V. Berezin,et al.  Structural basis for the activation of FGFR by NCAM , 2008, Protein science : a publication of the Protein Society.

[35]  G. Rechavi,et al.  Accumulation of Malignant Renal Stem Cells Is Associated with Epigenetic Changes in Normal Renal Progenitor Genes , 2008, Stem cells.

[36]  Gretchen M. Williams,et al.  Type I Pleuropulmonary Blastoma: Pathology and Biology Study of 51 Cases From the International Pleuropulmonary Blastoma Registry , 2008, The American journal of surgical pathology.

[37]  Gerhard Christofori,et al.  Neural cell adhesion molecule regulates the cellular response to fibroblast growth factor , 2007, Journal of Cell Science.

[38]  S. Reich-Zeliger,et al.  Isolation and characterization of nontubular sca-1+lin- multipotent stem/progenitor cells from adult mouse kidney. , 2006, Journal of the American Society of Nephrology : JASN.

[39]  Gareth Williams,et al.  The Fibroblast Growth Factor Receptor Acid Box Is Essential for Interactions with N-Cadherin and All of the Major Isoforms of Neural Cell Adhesion Molecule*♦ , 2006, Journal of Biological Chemistry.

[40]  C. Keet,et al.  Medulloblastoma Simulating Acute Myeloid Leukemia: Case Report With a Review of “Myeloid Antigen” Expression in Nonhematopoietic Tissues and Tumors , 2006, Journal of pediatric hematology/oncology.

[41]  Alexander Staab,et al.  A Phase I Dose Escalation Study with Anti-CD44v6 Bivatuzumab Mertansine in Patients with Incurable Squamous Cell Carcinoma of the Head and Neck or Esophagus , 2006, Clinical Cancer Research.

[42]  N. Kaminski,et al.  Multiple imprinted and stemness genes provide a link between normal and tumor progenitor cells of the developing human kidney. , 2006, Cancer research.

[43]  Claus Christensen,et al.  The neural cell adhesion molecule binds to fibroblast growth factor receptor 2 , 2006, FEBS letters.

[44]  Michael T. McManus,et al.  Dicer function is essential for lung epithelium morphogenesis , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[45]  K. Hongo,et al.  A case report and review of the literature , 2006, Journal of Neuro-Oncology.

[46]  V. Berezin,et al.  Molecular mechanisms of NCAM function. , 2004, Frontiers in bioscience : a journal and virtual library.

[47]  Elisabeth Bock,et al.  Structural basis for a direct interaction between FGFR1 and NCAM and evidence for a regulatory role of ATP. , 2003, Structure.

[48]  F. Kos,et al.  Costimulation of T cell receptor‐triggered IL‐2 production by Jurkat T cells via fibroblast growth factor receptor 1 upon its engagement by CD56 , 2002, Immunology and cell biology.

[49]  G. Christofori,et al.  N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling , 2001, Nature Cell Biology.

[50]  G. Edelman,et al.  N-CAM Binding Inhibits the Proliferation of Hippocampal Progenitor Cells and Promotes Their Differentiation to a Neuronal Phenotype , 2000, The Journal of Neuroscience.

[51]  F. Walsh,et al.  Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin , 1994, Neuron.

[52]  S. Shah,et al.  Immunoconjugates containing novel maytansinoids: promising anticancer drugs. , 1992, Cancer research.

[53]  W. Woods,et al.  Pleuropulmonary blastoma the so‐called pulmonary blastoma of childhood , 1988, Cancer.

[54]  H. S. Greene.  On the development of cancer. , 1948, Scientific American.