Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs.

[1]  P. Klatt,et al.  Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress. , 2000, European journal of biochemistry.

[2]  Y. Xu,et al.  Oxidation of zinc-binding cysteine residues in transcription factor proteins. , 2001, Antioxidants & redox signaling.

[3]  L. Presta,et al.  Antibody Humanization Using Monovalent Phage Display* , 1997, The Journal of Biological Chemistry.

[4]  C. Barbas,et al.  Direct selection for a catalytic mechanism from combinatorial antibody libraries. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[5]  L. Presta,et al.  X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling. , 1993, Journal of molecular biology.

[6]  P M van Wezenbeek,et al.  Nucleotide sequence of the filamentous bacteriophage M13 DNA genome: comparison with phage fd. , 1980, Gene.

[7]  Núria Romero-Isart,et al.  Advances in the structure and chemistry of metallothioneins. , 2002, Journal of inorganic biochemistry.

[8]  Damon L. Meyer,et al.  Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate , 2004, Clinical Cancer Research.

[9]  C. Anfinsen Principles that govern the folding of protein chains. , 1973, Science.

[10]  P. Carter,et al.  Sequence plasticity in the antigen-binding site of a therapeutic anti-HER2 antibody. , 2002, Journal of molecular biology.

[11]  S. Carroll,et al.  Cysteine analogs of recombinant barley ribosome inactivating protein form antibody conjugates with enhanced stability and potency in vitro. , 1994, Bioconjugate chemistry.

[12]  L. Presta,et al.  Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragments. , 1992, Biochemistry.

[13]  S. Wootton,et al.  Homo-Oligomerization of the Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein and the Role of Disulfide Linkages , 2003, Journal of Virology.

[14]  L. Presta,et al.  Humanization of an anti-p185HER2 antibody for human cancer therapy. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[15]  S. Betz Disulfide bonds and the stability of globular proteins , 1993, Protein science : a publication of the Protein Society.

[16]  Damon L. Meyer,et al.  Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity. , 2006, Bioconjugate chemistry.

[17]  M Aizawa,et al.  Assembling of engineered IgG-binding protein on gold surface for highly oriented antibody immobilization. , 2000, Journal of biotechnology.

[18]  P G Schultz,et al.  A method for directed evolution and functional cloning of enzymes. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[19]  J. Sambrook,et al.  Molecular Cloning: A Laboratory Manual , 2001 .

[20]  R. Feeney,et al.  Chemical modifications of proteins: history and applications. , 1990, Bioconjugate chemistry.

[21]  T. Clackson,et al.  In vitro selection from protein and peptide libraries. , 1994, Trends in biotechnology.

[22]  S. Sidhu,et al.  Bivalent antibody phage display mimics natural immunoglobulin. , 2004, Journal of immunological methods.

[23]  D. Powers,et al.  In vivo formation and stability of engineered disulfide bonds in subtilisin. , 1986, The Journal of biological chemistry.

[24]  Min Zhang,et al.  Albumin Binding as a General Strategy for Improving the Pharmacokinetics of Proteins* , 2002, The Journal of Biological Chemistry.

[25]  A. Glazer Specific chemical modification of proteins. , 1970, Annual review of biochemistry.

[26]  B. Matthews,et al.  Use of site-directed mutagenesis to obtain isomorphous heavy-atom derivatives for protein crystallography: cysteine-containing mutants of phage T4 lysozyme. , 1987, Protein engineering.

[27]  J. Marks,et al.  Toward selection of internalizing antibodies from phage libraries. , 1999, Biochemical and biophysical research communications.

[28]  R. Scheller,et al.  Rab14 is involved in membrane trafficking between the Golgi complex and endosomes. , 2004, Molecular biology of the cell.

[29]  J. Gutteridge,et al.  Thiols in cellular redox signalling and control. , 2001, Current medicinal chemistry.

[30]  R. Kelley,et al.  FAB Assembly and Enrichment in a Monovalent Phage Display System , 1991, Bio/Technology.

[31]  Phage display of peptide libraries on protein scaffolds. , 1998, Methods in molecular biology.

[32]  Sachdev S Sidhu,et al.  Exploring Protein–Protein Interactions with Phage Display , 2003, Chembiochem : a European journal of chemical biology.

[33]  I. Cotgreave,et al.  Recent trends in glutathione biochemistry--glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation? , 1998, Biochemical and biophysical research communications.

[34]  A. Kung,et al.  Gelonin analogs with engineered cysteine residues form antibody immunoconjugates with unique properties. , 1994, The Journal of biological chemistry.

[35]  A. Mercurio,et al.  Carbohydrate-binding protein 35 (Mac-2), a laminin-binding lectin, forms functional dimers using cysteine 186. , 1991, The Journal of biological chemistry.