The dynamics of microbial growth on soluble substrates: A unifying theory

Abstract This paper reviews the literature relevant to the dynamics of microbial growth on soluble substrates and integrates the knowledge obtained into a unifying theory describing that growth. In the unifying theory cellular mass is divided into five constituents: a synthetic component, a structural component, precursor molecules for those components, enzymes catalyzing the synthesis of the precursors, and storage products. Reactions governing the levels of those constituents are hypothesized. The literature shows that the transient response of a culture is generally either a storage response or a growth response and that environmental factors govern which response is manifested. The unifying theory is developed in a way which allows it to be simplified to either of those responses by proper selection of the rate constants in the reactions governing the levels of the cellular constituents.

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