Advances in flux balance analysis.

[1]  J. Davies,et al.  Molecular Biology of the Cell , 1983, Bristol Medico-Chirurgical Journal.

[2]  E. Papoutsakis Equations and calculations for fermentations of butyric acid bacteria , 1984, Biotechnology and bioengineering.

[3]  D. Fell,et al.  Fat synthesis in adipose tissue. An examination of stoichiometric constraints. , 1986, The Biochemical journal.

[4]  M. Domach,et al.  Simple constrained‐optimization view of acetate overflow in E. coli , 1990, Biotechnology and bioengineering.

[5]  B O Palsson,et al.  Optimal selection of metabolic fluxes for in vivo measurement. I. Development of mathematical methods. , 1992, Journal of theoretical biology.

[6]  B O Palsson,et al.  Optimal selection of metabolic fluxes for in vivo measurement. II. Application to Escherichia coli and hybridoma cell metabolism. , 1992, Journal of theoretical biology.

[7]  B. Palsson,et al.  Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates , 1993, Applied and environmental microbiology.

[8]  B. Palsson,et al.  Biochemical production capabilities of escherichia coli , 1993, Biotechnology and bioengineering.

[9]  B. Palsson,et al.  Metabolic capabilities of Escherichia coli: I. synthesis of biosynthetic precursors and cofactors. , 1993, Journal of theoretical biology.

[10]  B. Palsson,et al.  Metabolic Capabilities of Escherichia coli II. Optimal Growth Patterns , 1993 .

[11]  B. Palsson,et al.  Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110 , 1994, Applied and environmental microbiology.

[12]  J. Keasling,et al.  Stoichiometric model of Escherichia coli metabolism: incorporation of growth-rate dependent biomass composition and mechanistic energy requirements. , 1997, Biotechnology and bioengineering.

[13]  B. Palsson,et al.  How will bioinformatics influence metabolic engineering? , 1998, Biotechnology and bioengineering.

[14]  J. Keasling,et al.  Effect of Escherichia coli biomass composition on central metabolic fluxes predicted by a stoichiometric model. , 1998, Biotechnology and bioengineering.

[15]  B. Palsson,et al.  Toward Metabolic Phenomics: Analysis of Genomic Data Using Flux Balances , 1999, Biotechnology progress.

[16]  J. Edwards,et al.  Systems Properties of the Haemophilus influenzaeRd Metabolic Genotype* , 1999, The Journal of Biological Chemistry.

[17]  B. Palsson,et al.  The Escherichia coli MG1655 in silico metabolic genotype: its definition, characteristics, and capabilities. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[18]  L. Wackett Metabolic engineering , 2009, Nature biotechnology.

[19]  I. Grossmann,et al.  Recursive MILP model for finding all the alternate optima in LP models for metabolic networks , 2000 .

[20]  J. Edwards,et al.  Robustness Analysis of the Escherichiacoli Metabolic Network , 2000, Biotechnology progress.

[21]  Bernhard O. Palsson,et al.  Metabolic flux balance analysis and the in silico analysis of Escherichia coli K-12 gene deletions , 2000, BMC Bioinformatics.

[22]  B. Palsson,et al.  Combining pathway analysis with flux balance analysis for the comprehensive study of metabolic systems. , 2000, Biotechnology and bioengineering.

[23]  A. Burgard,et al.  Probing the performance limits of the Escherichia coli metabolic network subject to gene additions or deletions. , 2001, Biotechnology and bioengineering.

[24]  B. Palsson,et al.  In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data , 2001, Nature Biotechnology.

[25]  C Phalakornkule,et al.  A MILP-based flux alternative generation and NMR experimental design strategy for metabolic engineering. , 2001, Metabolic engineering.

[26]  B. Palsson,et al.  Regulation of gene expression in flux balance models of metabolism. , 2001, Journal of theoretical biology.

[27]  B O Palsson,et al.  Flux-balance analysis of mitochondrial energy metabolism: consequences of systemic stoichiometric constraints. , 2001, American journal of physiology. Regulatory, integrative and comparative physiology.

[28]  B. Palsson,et al.  Characterizing the metabolic phenotype: A phenotype phase plane analysis , 2002, Biotechnology and bioengineering.

[29]  M. Lidstrom,et al.  Stoichiometric model for evaluating the metabolic capabilities of the facultative methylotroph Methylobacterium extorquens AM1, with application to reconstruction of C(3) and C(4) metabolism. , 2002, Biotechnology and bioengineering.

[30]  B. Palsson,et al.  Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth , 2002, Nature.

[31]  Steffen Klamt,et al.  Calculability analysis in underdetermined metabolic networks illustrated by a model of the central metabolism in purple nonsulfur bacteria. , 2002, Biotechnology and bioengineering.

[32]  F. Doyle,et al.  Dynamic flux balance analysis of diauxic growth in Escherichia coli. , 2002, Biophysical journal.

[33]  H. Qian,et al.  Energy balance for analysis of complex metabolic networks. , 2002, Biophysical journal.

[34]  G. Church,et al.  Genome-Scale Metabolic Model of Helicobacter pylori 26695 , 2002, Journal of bacteriology.

[35]  Jason A. Papin,et al.  The genome-scale metabolic extreme pathway structure in Haemophilus influenzae shows significant network redundancy. , 2002, Journal of theoretical biology.

[36]  B. Palsson,et al.  Transcriptional regulation in constraints-based metabolic models of Escherichia coli Covert , 2002 .

[37]  G. Church,et al.  Analysis of optimality in natural and perturbed metabolic networks , 2002 .

[38]  A. Burgard,et al.  Optimization-based framework for inferring and testing hypothesized metabolic objective functions. , 2003, Biotechnology and bioengineering.

[39]  B. Palsson,et al.  Constraints-based models: regulation of gene expression reduces the steady-state solution space. , 2003, Journal of theoretical biology.

[40]  B. Palsson,et al.  Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network. , 2003, Genome research.

[41]  Miguel A. Andrade-Navarro,et al.  Evaluation of annotation strategies using an entire genome sequence , 2003, Bioinform..

[42]  Steffen Klamt,et al.  Calculating as Many Fluxes as Possible in Underdetermined Metabolic Networks , 2004, Molecular Biology Reports.