Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

[1]  P. Nuutila Brown adipose tissue. , 2016, Best practice & research. Clinical endocrinology & metabolism.

[2]  A. Doria,et al.  Activation of human brown adipose tissue by a β3-adrenergic receptor agonist. , 2015, Cell metabolism.

[3]  S. Kersten,et al.  Brown adipose tissue takes up plasma triglycerides mostly after lipolysis , 2015, Journal of Lipid Research.

[4]  W. D. van Marken Lichtenbelt,et al.  Brown adipose tissue volume in healthy lean south Asian adults compared with white Caucasians: a prospective, case-controlled observational study. , 2014, The lancet. Diabetes & endocrinology.

[5]  M. Lombès,et al.  Metformin Lowers Plasma Triglycerides by Promoting VLDL-Triglyceride Clearance by Brown Adipose Tissue in Mice , 2014, Diabetes.

[6]  J. Heeren,et al.  Adipose tissue browning and metabolic health , 2014, Nature Reviews Endocrinology.

[7]  N. Petrovic,et al.  UCP1 in brite/beige adipose tissue mitochondria is functionally thermogenic. , 2013, Cell reports.

[8]  P. Seale,et al.  Brown and beige fat: development, function and therapeutic potential , 2013, Nature Medicine.

[9]  Mami Matsushita,et al.  Recruited brown adipose tissue as an antiobesity agent in humans. , 2013, The Journal of clinical investigation.

[10]  Felix M Mottaghy,et al.  Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. , 2013, The Journal of clinical investigation.

[11]  Baocun Sun,et al.  Cold Exposure Promotes Atherosclerotic Plaque Growth and Instability via UCP1-Dependent Lipolysis , 2013, Cell metabolism.

[12]  J. Jukema,et al.  Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol , 2013, PloS one.

[13]  B. Spiegelman,et al.  Adaptive thermogenesis in adipocytes: is beige the new brown? , 2013, Genes & development.

[14]  P. Lishko,et al.  Mechanism of Fatty-Acid-Dependent UCP1 Uncoupling in Brown Fat Mitochondria , 2012, Cell.

[15]  C. Cannon,et al.  The controversies of statin therapy: weighing the evidence. , 2012, Journal of the American College of Cardiology.

[16]  J. Heeren,et al.  The holy grail of metabolic disease: brown adipose tissue , 2012, Current opinion in lipidology.

[17]  H. S. Nielsen,et al.  Weighing the evidence , 2012, Acta obstetricia et gynecologica Scandinavica.

[18]  J. Romijn,et al.  Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE*3-Leiden mice. , 2012, Atherosclerosis.

[19]  J. Heeren,et al.  A new, powerful player in lipoprotein metabolism: brown adipose tissue , 2012, Journal of Molecular Medicine.

[20]  M. Zhang,et al.  Brown Adipose Tissue in Humans Is Activated by Elevated Plasma Catecholamines Levels and Is Inversely Related to Central Obesity , 2011, PloS one.

[21]  W. D. van Marken Lichtenbelt,et al.  Brown Adipose Tissue in Morbidly Obese Subjects , 2011, PloS one.

[22]  Oliver T. Bruns,et al.  Brown adipose tissue activity controls triglyceride clearance , 2011, Nature Medicine.

[23]  J. Stichler Weighing the Evidence , 2010, HERD.

[24]  K. V. van Dijk,et al.  Fenofibrate Increases Very Low Density Lipoprotein Triglyceride Production Despite Reducing Plasma Triglyceride Levels in APOE*3-Leiden.CETP Mice* , 2010, The Journal of Biological Chemistry.

[25]  M. Ruth Cold-Activated Brown Adipose Tissue in Healthy Men , 2010 .

[26]  J. Orava,et al.  Functional brown adipose tissue in healthy adults. , 2009, The New England journal of medicine.

[27]  Jan Nedergaard,et al.  The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[28]  E. Palmer,et al.  Identification and importance of brown adipose tissue in adult humans. , 2009, The New England journal of medicine.

[29]  J. Jukema,et al.  Torcetrapib Does Not Reduce Atherosclerosis Beyond Atorvastatin and Induces More Proinflammatory Lesions Than Atorvastatin , 2008, Circulation.

[30]  T. Bengtsson,et al.  Unexpected evidence for active brown adipose tissue in adult humans. , 2007, American journal of physiology. Endocrinology and metabolism.

[31]  J. Heeren,et al.  Apolipoprotein E recycling: implications for dyslipidemia and atherosclerosis. , 2005, Arteriosclerosis, thrombosis, and vascular biology.

[32]  Jan Nedergaard,et al.  Brown adipose tissue: function and physiological significance. , 2004, Physiological reviews.

[33]  A. Buck,et al.  Brown adipose tissue: a factor to consider in symmetrical tracer uptake in the neck and upper chest region , 2002, European Journal of Nuclear Medicine and Molecular Imaging.

[34]  T. V. van Berkel,et al.  Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice. , 2001, Journal of lipid research.

[35]  V. Kakkar,et al.  Central cooling effects in patients with hypercholesterolaemia. , 1998, Clinical science.

[36]  T. V. van Berkel,et al.  Particle size determines the specificity of apolipoprotein E-containing triglyceride-rich emulsions for the LDL receptor versus hepatic remnant receptor in vivo. , 1997, Journal of lipid research.

[37]  J. K. Kruijt,et al.  Selective liver targeting of antivirals by recombinant chylomicrons — a new therapeutic approach to hepatitis B , 1995, Nature Medicine.

[38]  R. Frants,et al.  Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice. , 1994, The Journal of clinical investigation.

[39]  N. Sakane,et al.  Anti-obesity and anti-diabetic effects of CL 316,243, a highly specific beta 3-adrenoceptor agonist, in yellow KK mice. , 1994, Life sciences.

[40]  R. Hammer,et al.  Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. , 1993, The Journal of clinical investigation.

[41]  N. Maeda,et al.  Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. , 1992, Science.

[42]  E. Rubin,et al.  Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells , 1992, Cell.

[43]  T. V. van Berkel,et al.  Characterization of the chylomicron-remnant-recognition sites on parenchymal and Kupffer cells of rat liver. Selective inhibition of parenchymal cell recognition by lactoferrin. , 1992, European journal of biochemistry.

[44]  F. Péronnet,et al.  Table of nonprotein respiratory quotient: an update. , 1991, Canadian journal of sport sciences = Journal canadien des sciences du sport.

[45]  D. Miller,et al.  Energy balance following sympathetic denervation of brown adipose tissue. , 1984, Canadian journal of physiology and pharmacology.

[46]  K. Johnson An Update. , 1984, Journal of food protection.

[47]  N. Rothwell,et al.  A role for brown adipose tissue in diet-induced thermogenesis. , 1997, Nature.

[48]  W. James,et al.  Thermogenic defect in pre-obese ob/ob mice , 1977, Nature.

[49]  Saunders Kb [The brown adipose tissue]. , 1965, Il Policlinico. Sezione pratica.