The 16p11.2 Deletion Mouse Model of Autism Exhibits Altered Cortical Progenitor Proliferation and Brain Cytoarchitecture Linked to the ERK MAPK Pathway
暂无分享,去创建一个
Joseph Vithayathil | G. Landreth | Gary E. Landreth | J. Pucilowska | Joanna Pucilowska | Emmanuel J. Tavares | Caitlin Kelly | J. Colleen Karlo | J. Vithayathil | E. J. Tavares | J. Karlo | C. Kelly
[1] Yasushi Kobayashi,et al. ERK2 Contributes to the Control of Social Behaviors in Mice , 2011, The Journal of Neuroscience.
[2] Yasushi Kobayashi,et al. Deletion of ERK1 and ERK2 in the CNS Causes Cortical Abnormalities and Neonatal Lethality: Erk1 Deficiency Enhances the Impairment of Neurogenesis in Erk2-Deficient Mice , 2011, The Journal of Neuroscience.
[3] M. Ross,et al. Differences in cyclin D2 and D1 protein expression distinguish forebrain progenitor subsets. , 2007, Cerebral cortex.
[4] Abraham Z. Snyder,et al. Opposing Brain Differences in 16p11.2 Deletion and Duplication Carriers , 2014, The Journal of Neuroscience.
[5] S. Lodato,et al. Excitatory Projection Neuron Subtypes Control the Distribution of Local Inhibitory Interneurons in the Cerebral Cortex , 2011, Neuron.
[6] Daniel P. Kennedy,et al. Mapping Early Brain Development in Autism , 2007, Neuron.
[7] Andreas Buja,et al. Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism , 2011, Proceedings of the National Academy of Sciences.
[8] D. Ginty,et al. Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development , 2008, Proceedings of the National Academy of Sciences.
[9] G. Landreth,et al. ERK1-Deficient Mice Show Normal T Cell Effector Function and Are Highly Susceptible to Experimental Autoimmune Encephalomyelitis1 , 2005, The Journal of Immunology.
[10] W. Huttner,et al. An inhibition of cyclin-dependent kinases that lengthens, but does not arrest, neuroepithelial cell cycle induces premature neurogenesis , 2003, Journal of Cell Science.
[11] M. Ross,et al. Cyclin D2 Is Critical for Intermediate Progenitor Cell Proliferation in the Embryonic Cortex , 2009, The Journal of Neuroscience.
[12] J. Bartek,et al. Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint , 1996, Molecular and cellular biology.
[13] E. Wiemer,et al. The Major Vault Protein Is a Novel Substrate for the Tyrosine Phosphatase SHP-2 and Scaffold Protein in Epidermal Growth Factor Signaling* , 2004, Journal of Biological Chemistry.
[14] A. Kriegstein,et al. The role of intermediate progenitor cells in the evolutionary expansion of the cerebral cortex. , 2006, Cerebral cortex.
[15] A. Kriegstein,et al. Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases , 2004, Nature Neuroscience.
[16] N. Minshew,et al. The new neurobiology of autism: cortex, connectivity, and neuronal organization. , 2007, Archives of neurology.
[17] J. Sweatt,et al. Deletion of ERK2 Mitogen-Activated Protein Kinase Identifies Its Key Roles in Cortical Neurogenesis and Cognitive Function , 2008, The Journal of Neuroscience.
[18] D. Conrad,et al. Recurrent 16p11.2 microdeletions in autism. , 2007, Human molecular genetics.
[19] R. Adolphs,et al. Agenesis of the corpus callosum: genetic, developmental and functional aspects of connectivity , 2007, Nature Reviews Neuroscience.
[20] B. Gelb,et al. Disorders of dysregulated signal traffic through the RAS‐MAPK pathway: phenotypic spectrum and molecular mechanisms , 2010, Annals of the New York Academy of Sciences.
[21] J. Rubenstein,et al. Repression of Fgf Signaling by Sprouty1-2 Regulates Cortical Patterning in Two Distinct Regions and Times , 2010, The Journal of Neuroscience.
[22] A. Kriegstein,et al. Patterns of neural stem and progenitor cell division may underlie evolutionary cortical expansion , 2006, Nature Reviews Neuroscience.
[23] Boris Yamrom,et al. Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders , 2011, Neuron.
[24] N Hadjikhani,et al. The 16p11.2 locus modulates brain structures common to autism, schizophrenia and obesity , 2014, Molecular Psychiatry.
[25] Jessica R. Wolff,et al. Microduplications of 16p11.2 are Associated with Schizophrenia , 2009, Nature Genetics.
[26] V. Tarabykin,et al. Cortical upper layer neurons derive from the subventricular zone as indicated by Svet1 gene expression. , 2001, Development.
[27] Suzanne Schubbert,et al. Deregulated Ras signaling in developmental disorders: new tricks for an old dog. , 2007, Current opinion in genetics & development.
[28] James M. Roberts,et al. CDK inhibitors: positive and negative regulators of G1-phase progression. , 1999, Genes & development.
[29] J. Sweatt,et al. Molecular psychology: roles for the ERK MAP kinase cascade in memory. , 2002, Annual review of pharmacology and toxicology.
[30] R. Malenka,et al. Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome. , 2014, Cell reports.
[31] Gord Fishell,et al. Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain , 2000, Neuron.
[32] Yan Yan,et al. MVP interacts with YPEL4 and inhibits YPEL4-mediated activities of the ERK signal pathway. , 2010, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[33] K. Rauen,et al. The RASopathies. , 2013, Annual review of genomics and human genetics.
[34] C. Freitag,et al. Total Brain Volume and Corpus Callosum Size in Medication-Naïve Adolescents and Young Adults with Autism Spectrum Disorder , 2009, Biological Psychiatry.
[35] S. Saitta,et al. MAP'ing CNS Development and Cognition: An ERKsome Process , 2009, Neuron.
[36] Pavel A. Puzerey,et al. Disrupted ERK Signaling during Cortical Development Leads to Abnormal Progenitor Proliferation, Neuronal and Network Excitability and Behavior, Modeling Human Neuro-Cardio-Facial-Cutaneous and Related Syndromes , 2012, The Journal of Neuroscience.
[37] Christian R Marshall,et al. Phenotypic spectrum associated with de novo and inherited deletions and duplications at 16p11.2 in individuals ascertained for diagnosis of autism spectrum disorder , 2009, Journal of Medical Genetics.
[38] R. Roskoski. ERK1/2 MAP kinases: structure, function, and regulation. , 2012, Pharmacological research.
[39] M. Götz,et al. Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage. , 2000, Development.
[40] Stephen J. Guter,et al. Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders , 2014, American journal of human genetics.
[41] Joshua M. Korn,et al. Association between microdeletion and microduplication at 16p11.2 and autism. , 2008, The New England journal of medicine.
[42] H. Okano,et al. Differential expression of Pax6 and Ngn2 between pair‐generated cortical neurons , 2004, Journal of neuroscience research.
[43] Henry Kennedy,et al. Cell-cycle control and cortical development , 2007, Nature Reviews Neuroscience.
[44] C. Walsh,et al. Human brain malformations and their lessons for neuronal migration. , 2001, Annual review of neuroscience.
[45] W. Huttner,et al. Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors. , 2009, Cell stem cell.
[46] H. Kalkman. Potential opposite roles of the extracellular signal-regulated kinase (ERK) pathway in autism spectrum and bipolar disorders , 2012, Neuroscience & Biobehavioral Reviews.
[47] S. Endo,et al. ERK1 and ERK2 are required for radial glial maintenance and cortical lamination , 2010, Genes to cells : devoted to molecular & cellular mechanisms.
[48] KouichiC . Nakamura,et al. Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[49] J. Pouysségur,et al. Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. , 2003, Biochemical pharmacology.
[50] T. Weissman,et al. Neurons derived from radial glial cells establish radial units in neocortex , 2001, Nature.
[51] Kathryn Roeder,et al. Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism , 2011, Neuron.
[52] C. Englund,et al. Pax6, Tbr2, and Tbr1 Are Expressed Sequentially by Radial Glia, Intermediate Progenitor Cells, and Postmitotic Neurons in Developing Neocortex , 2005, The Journal of Neuroscience.
[53] Tomoki Nakamura,et al. Noonan syndrome is associated with enhanced pERK activity, the repression of which can prevent craniofacial malformations , 2009, Proceedings of the National Academy of Sciences.
[54] R. Brambilla,et al. Lentiviral vectors to study the differential function of ERK1 and ERK2 MAP kinases. , 2010, Methods in molecular biology.
[55] J. Sweatt,et al. Mice lacking the ERK1 isoform of MAP kinase are unimpaired in emotional learning. , 2001, Learning & memory.
[56] Winfried Denk,et al. Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[57] Pat Levitt,et al. The genetic and neurobiologic compass points toward common signaling dysfunctions in autism spectrum disorders. , 2009, The Journal of clinical investigation.
[58] S. Mcconnell,et al. Cell cycle dependence of laminar determination in developing neocortex. , 1992, Science.