Factors of variation and the techniques for improving extraction and bioaccessibility of carob polyphenol: a review

[1]  F. Ozogul,et al.  Recent Developments in Polyphenol Applications on Human Health: A Review with Current Knowledge , 2023, Plants.

[2]  G. Nieto,et al.  Process Optimization of Phytoantioxidant and Photoprotective Compounds from Carob Pods (Ceratonia siliqua L.) Using Ultrasonic Assisted Extraction Method , 2022, Molecules.

[3]  L. Grumetto,et al.  Recent Advances in Natural Polyphenol Research , 2022, Molecules.

[4]  Bouchelouche Asma,et al.  Ethnobotanical knowledge and socio-economic importance of Ceratonia siliqua L (Fabaceae) in the North of Setif (North-East of Algeria) , 2022, Acta Ecologica Sinica.

[5]  Yassine El Ghallab,et al.  Ethnopharmacological Survey of Plants Prescribed by Herbalists for Traditional Treatment of Hypercholesterolemia in Casablanca, Morocco , 2022, Journal of Herbal Medicine.

[6]  A. Jambrak,et al.  Green, environment-friendly and sustainable techniques for extraction of food bioactive compounds and waste valorization , 2022, Trends in Food Science & Technology.

[7]  I. Stavrou,et al.  HPLC-ESI-HRMS and Chemometric Analysis of Carobs Polyphenols – Technological and Geographical Parameters Affecting their Phenolic Composition , 2022, Journal of Food Composition and Analysis.

[8]  M. Ajjoun,et al.  Moroccan medicinal plants traditionally used for the treatment of skin diseases: From ethnobotany to clinical trials. , 2022, Journal of ethnopharmacology.

[9]  M. L. Clodoveo,et al.  Kefir Enriched with Carob (Ceratonia siliqua L.) Leaves Extract as a New Ingredient during a Gluten-Free Bread-Making Process , 2022, Fermentation.

[10]  Ola Shalabi.  Antioxidant, antibacterial, and antitumor activities of goat's stirred yoghurt fortified with carob molasses , 2022, Annals of Agricultural Sciences.

[11]  Cristina L. M. Silva,et al.  Particle Size Effect of Integral Carob Flour on Bioaccessibility of Bioactive Compounds during Simulated Gastrointestinal Digestion , 2022, Foods.

[12]  A. Mohamed,et al.  The Use of Medicinal Plants Against Cancer: An Ethnobotanical Study in the Beni Mellal-Khenifra Region in Morocco , 2022, European Journal of Integrative Medicine.

[13]  G. Bonanomi,et al.  Metabolomics and chemometrics of seven aromatic plants: Carob, eucalyptus, laurel, mint, myrtle, rosemary and strawberry tree. , 2022, Phytochemical analysis : PCA.

[14]  S. Mandal,et al.  Ethnobotanical, pharmacological, phytochemical, and clinical investigations on Moroccan medicinal plants traditionally used for the management of renal dysfunctions. , 2022, Journal of ethnopharmacology.

[15]  C. Nerín,et al.  Ceratonia siliqua L. kibbles, seeds and leaves as a source of volatile bioactive compounds for antioxidant food biopackaging applications , 2022, Food Packaging and Shelf Life.

[16]  A. Rašković,et al.  Hepatoprotective Effect of Carob Pulp Flour (Ceratonia siliqua L.) Extract Obtained by Optimized Microwave-Assisted Extraction , 2022, Pharmaceutics.

[17]  M. L. Clodoveo,et al.  Ultrasound Assisted Extraction of Polyphenols from Ripe Carob Pods (Ceratonia siliqua L.): Combined Designs for Screening and Optimizing the Processing Parameters , 2022, Foods.

[18]  M. Pouzar,et al.  Bioaccessibility of phenolics from carob (Ceratonia siliqua L.) pod powder prepared by cryogenic and vibratory grinding , 2021, Food Chemistry.

[19]  Eftychia Pinakoulaki,et al.  Linking the Dynamic Changes in the In Vitro Antioxidant Activity of Carob Kibbles upon Roasting to the Chemical and Structural Changes Revealed by FTIR Spectroscopy , 2021, Antioxidants.

[20]  C. Nerín,et al.  Novel active biopackaging incorporated with macerate of carob (Ceratonia siliqua L.) to extend shelf-life of stored Atlantic salmon fillets (Salmo salar L.). , 2021, LWT.

[21]  I. E. El Sayed,et al.  Phytochemical Characterization and Evaluation of Biological Activities of Egyptian Carob Pods (Ceratonia siliqua L.) Aqueous Extract: In Vitro Study , 2021, Plants.

[22]  Cristina L. M. Silva,et al.  Carob bean (Ceratonia siliqua L.): A new perspective for functional food , 2021 .

[23]  A. Delgado,et al.  Sustainability Opportunities for Mediterranean Food Products through New Formulations Based on Carob Flour (Ceratonia siliqua L.) , 2021, Sustainability.

[24]  I. Stavrou,et al.  Continuous and pulsed ultrasound-assisted extraction of carob’s antioxidants: Processing parameters optimization and identification of polyphenolic composition , 2021, Ultrasonics sonochemistry.

[25]  Filipa S. Reis,et al.  Chemical characterization of carob seeds (Ceratonia siliqua L.) and use of different extraction techniques to promote its bioactivity. , 2021, Food chemistry.

[26]  M. Esteban,et al.  Phytochemical Compounds and Biological Properties of Carob Pods (Ceratonia siliqua L.) Extracts at Different Ripening Stages , 2021, Waste and Biomass Valorization.

[27]  L. Papayiannis,et al.  Pod Morphology, Primary and Secondary Metabolite Profiles in Non-grafted and Grafted Carob Germplasm Are Configured by Agro-Environmental Zone, Genotype, and Growing Season , 2021, Frontiers in Plant Science.

[28]  F. Fadel,et al.  Morphometric and physicochemical characteristics of carob pods in three geographical regions of Morocco , 2020, SN Applied Sciences.

[29]  G. Granata,et al.  Carob Seeds: Food Waste or Source of Bioactive Compounds? , 2020, Pharmaceutics.

[30]  Y. Rouphael,et al.  Heat- and Ultrasound-Assisted Aqueous Extraction of Soluble Carbohydrates and Phenolics from Carob Kibbles of Variable Size and Source Material , 2020, Foods.

[31]  M. Ferrando,et al.  Low-energy membrane-based processes to concentrate and encapsulate polyphenols from carob pulp , 2020 .

[32]  A. Garcimartín,et al.  Carob fruit extract-enriched meat improves pancreatic beta-cell dysfunction, hepatic insulin signaling and lipogenesis in late-stage type 2 diabetes mellitus model. , 2020, The Journal of nutritional biochemistry.

[33]  Tafirenyika Nyamayaro Madzimbamuto,et al.  Applications of Nonconventional Green Extraction Technologies in Process Industries: Challenges, Limitations and Perspectives , 2020 .

[34]  O. Cioancă,et al.  The Aqueous Extract from Ceratonia siliqua Leaves Protects against 6-Hydroxydopamine in Zebrafish: Understanding the Underlying Mechanism , 2020, Antioxidants.

[35]  S. Iwamoto,et al.  Encapsulation for Improving in Vitro Gastrointestinal Digestion of Plant Polyphenols and Their Applications in Food Products , 2020, Food Reviews International.

[36]  M. Esteban,et al.  An in vitro study of the effect of carob (Ceratonia siliqua L.) leaf extracts on gilthead seabream (Sparus aurata L.) leucocyte activities. Antioxidant, cytotoxic and bactericidal properties. , 2020, Fish & shellfish immunology.

[37]  A. Stoyanova,et al.  Evaluation of chemical composition, antioxidant potential and functional properties of carob (Ceratonia siliqua L.) seeds , 2020, Journal of Food Science and Technology.

[38]  V. Goulas,et al.  Utilization of Carob Fruit as Sources of Phenolic Compounds with Antioxidant Potential: Extraction Optimization and Application in Food Models , 2019, Foods.

[39]  M. Bachir bey,et al.  Changes in anticholinesterase, antioxidant activities and related bioactive compounds of carob pulp (Ceratonia siliqua L.) during ripening stages , 2019, Journal of Food Measurement and Characterization.

[40]  J. Zhao,et al.  Functional polysaccharides of carob fruit: a review , 2019, Chinese Medicine.

[41]  V. Goulas,et al.  Valorization of Carob Fruit Residues for the Preparation of Novel Bi-Functional Polyphenolic Coating for Food Packaging Applications , 2019, Molecules.

[42]  O. Yıldız,et al.  Glucose-mediated protein glycation: Contribution of methanolic extract of Ceratonia siliqua L. in protection and in vitro potential inhibition of acetylcholinesterase. , 2019, Journal of food biochemistry.

[43]  M. C. Garrigós,et al.  Optimization of Microwave-Assisted Extraction of Phenolic Compounds with Antioxidant Activity from Carob Pods , 2019, Food Analytical Methods.

[44]  A. Agapiou,et al.  GC-MS analysis of D-pinitol in carob: Syrup and fruit (flesh and seed). , 2019, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[45]  V. Goulas,et al.  Dynamic changes in targeted phenolic compounds and antioxidant potency of carob fruit (Ceratonia siliqua L.) products during in vitro digestion , 2019, LWT.

[46]  C. Martínez-Villaluenga,et al.  In vitro approach for evaluation of carob by-products as source bioactive ingredients with potential to attenuate metabolic syndrome (MetS) , 2019, Heliyon.

[47]  P. Correia,et al.  Exploratory Analysis of the Productivity of Carob Tree (Ceratonia siliqua) Orchards Conducted under Dry-Farming Conditions , 2018, Sustainability.

[48]  Eftychia Pinakoulaki,et al.  Carob as cocoa substitute: a review on composition, health benefits and food applications , 2018, European Food Research and Technology.

[49]  P. Correia,et al.  Biologically active compounds available in Ceratonia siliqua L. grown in contrasting soils under Mediterranean climate , 2018 .

[50]  Muhammad Kamran Khan,et al.  Process optimization of polyphenol extraction from carob (Ceratonia siliqua) kibbles using microwave-assisted technique , 2018 .

[51]  El Bouzdoudi Brahim,et al.  Total Polyphenols and Gallic Acid Contents in Domesticated Carob (Ceratonia siliqua L.) Pods and Leaves , 2017 .

[52]  A. Hichami,et al.  Carob leaf polyphenols trigger intrinsic apoptotic pathway and induce cell cycle arrest in colon cancer cells , 2017 .

[53]  M. Farag,et al.  Volatiles profiling in Ceratonia siliqua (Carob bean) from Egypt and in response to roasting as analyzed via solid-phase microextraction coupled to chemometrics , 2017, Journal of advanced research.

[54]  R. López-Nicolás,et al.  Effect of in Vitro Gastrointestinal Digestion on Encapsulated and Nonencapsulated Phenolic Compounds of Carob (Ceratonia siliqua L.) Pulp Extracts and Their Antioxidant Capacity. , 2017, Journal of agricultural and food chemistry.

[55]  Brahim El Bouzdoudi,et al.  Determination of Polyphenols Content in Carob Pulp from Wild and Domesticated Moroccan Trees , 2016 .

[56]  Ş. Karataş,et al.  Chemical and biological approaches on nine fruit tree leaves collected from the Mediterranean region of Turkey , 2016 .

[57]  M. Świeca,et al.  Effect of carob (Ceratonia siliqua L.) flour on the antioxidant potential, nutritional quality, and sensory characteristics of fortified durum wheat pasta. , 2016, Food chemistry.

[58]  Muhammad Kamran Khan,et al.  Carob Kibble: A Bioactive-Rich Food Ingredient. , 2016, Comprehensive reviews in food science and food safety.

[59]  Hatem Fessi,et al.  Double emulsion solvent evaporation techniques used for drug encapsulation. , 2015, International journal of pharmaceutics.

[60]  B. George,et al.  Changes in bioactive phytochemical content and in vitro antioxidant activity of carob (Ceratonia siliqua L.) as influenced by fruit ripening , 2014 .

[61]  Irfan Turhan,et al.  Mineral composition of pods and seeds of wild and grafted carob (Ceratonia siliqua L.) fruits , 2014 .

[62]  M. Strnad,et al.  Phenolic Acid Content and Free Radical-Scavenging Activity of Two Differently Processed Carob Tree ( Ceratonia siliqua L.) Pod , 2013 .

[63]  L. Duarte,et al.  Supercritical, ultrasound and conventional extracts from carob (Ceratonia siliqua L.) biomass: Effect on the phenolic profile and antiproliferative activity , 2013 .

[64]  M. Ozturk,et al.  Compositional changes of major chemical compounds in Greek carob pods during development , 2012 .

[65]  S. Jaoua,et al.  Characterization of bioactive compounds and ameliorative effects of Ceratonia siliqua leaf extract against CCl₄ induced hepatic oxidative damage and renal failure in rats. , 2011, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[66]  F. Girio,et al.  Supercritical extraction of carob kibbles (Ceratonia siliqua L.) , 2011 .

[67]  M. Özcan,et al.  Lipid evaluation of cultivated and wild carob (Ceratonia siliqua L.) seed oil growing in Turkey , 2011 .

[68]  M. Lachkar,et al.  Antioxidant activity, phytochemical screening, and total phenolic content of extracts from three genders of carob tree barks growing in Morocco , 2011 .

[69]  F. Albericio,et al.  Antioxidant and cytotoxic activities of carob tree fruit pulps are strongly influenced by gender and cultivar. , 2011, Journal of agricultural and food chemistry.

[70]  F. Albericio,et al.  Phytochemical Profile, Antioxidant and Cytotoxic Activities of the Carob Tree (Ceratonia siliqua L.) Germ Flour Extracts , 2011, Plant foods for human nutrition.

[71]  M. Balaban.  Identification of the main phenolic compounds in wood of Ceratonia siliqua by GC-MS. , 2004, Phytochemical Analysis.

[72]  R. Galensa,et al.  Identification and quantification of polyphenols in carob fruits (Ceratonia siliqua L.) and derived products by HPLC-UV-ESI/MSn. , 2004, Journal of agricultural and food chemistry.

[73]  G. Ouzounidou,et al.  Carob as an Agrifood Chain Product of Cultural, Agricultural and Economic Importance in the Mediterranean Region , 2023, Journal of Innovation Economics & Management.

[74]  A. Douira,et al.  Ethnoveterinary medicines plants for animal therapy in the Rif, North of Morocco. , 2022, South African Journal of Botany.

[75]  A. Garcimartín,et al.  Carob-fruit-extract-enriched meat modulates lipoprotein metabolism and insulin signaling in diabetic rats induced by high-saturated-fat diet , 2020 .

[76]  Y. Chait,et al.  Simulated gastrointestinal digestion and in vitro colonic fermentation of carob polyphenols: Bioaccessibility and bioactivity , 2020, LWT.

[77]  S. Sanchez-Segado,et al.  Algerian Carob Tree Products: A Comprehensive Valorization Analysis and Future Prospects , 2018 .

[78]  F. Chemat,et al.  Influence of Roasting on Sensory, Antioxidant, Aromas, and Physicochemical Properties of Carob Pod Powder (Ceratonia siliqua L.) , 2017 .

[79]  F. Chemat,et al.  Ultrasound assisted extraction of food and natural products. Mechanisms, techniques, combinations, protocols and applications. A review. , 2017, Ultrasonics sonochemistry.

[80]  J. Roseiro,et al.  Antioxidants from aqueous decoction of carob pods biomass (Ceretonia siliqua L.): Optimisation using response surface methodology and phenolic profile by capillary electrophoresis , 2013 .

[81]  M. Motilva,et al.  Matrix composition effect on the digestibility of carob flour phenols by an in-vitro digestion model , 2011 .

[82]  M. Paquot,et al.  Isolation and chemical evaluation of carob (Ceratonia siliqua L.) seed germ , 2007 .