Sugarcane (Saccharum X officinarum): A Reference Study for the Regulation of Genetically Modified Cultivars in Brazil

Global interest in sugarcane has increased significantly in recent years due to its economic impact on sustainable energy production. Sugarcane breeding and better agronomic practices have contributed to a huge increase in sugarcane yield in the last 30 years. Additional increases in sugarcane yield are expected to result from the use of biotechnology tools in the near future. Genetically modified (GM) sugarcane that incorporates genes to increase resistance to biotic and abiotic stresses could play a major role in achieving this goal. However, to bring GM sugarcane to the market, it is necessary to follow a regulatory process that will evaluate the environmental and health impacts of this crop. The regulatory review process is usually accomplished through a comparison of the biology and composition of the GM cultivar and a non-GM counterpart. This review intends to provide information on non-GM sugarcane biology, genetics, breeding, agronomic management, processing, products and byproducts, as well as the current technologies used to develop GM sugarcane, with the aim of assisting regulators in the decision-making process regarding the commercial release of GM sugarcane cultivars.

[1]  Ariel Arencibia,et al.  Production of transgenic sugarcane (Saccharum officinarum L.) plants by intact cell electroporation , 1995, Plant Cell Reports.

[2]  M. Julien Physiology of Flowering in Saccharum I. DAYLENGTH CONTROL OF FLORAL INITIATION AND DEVELOPMENT IN S. SPONTANEUM L. , 1973 .

[3]  S. Gupta-Bhattacharya,et al.  Differences in concentrations of allergenic pollens and spores at different heights on an agricultural farm in West Bengal, India. , 2001, Annals of agricultural and environmental medicine : AAEM.

[4]  G. Bremer Problems in breeding and cytology of sugar cane , 1961, Euphytica.

[5]  C. Grof,et al.  Green-fluorescent protein facilitates rapid in vivo detection of genetically transformed plant cells , 1999, Plant Cell Reports.

[6]  Genera graminum: Grasses of the World , 1987 .

[7]  W. W. Bailey The Grasses , 1871, The American Naturalist.

[8]  L. Sreebny,et al.  Sugar availability, sugar consumption and dental caries. , 1982, Community dentistry and oral epidemiology.

[9]  G. Bremer Problems in breeding and cytology of sugar cane , 1961, Euphytica.

[10]  M. Silva-Filho,et al.  Expression of the Cry1Ab Protein in Genetically Modified Sugarcane for the Control of Diatraea saccharalis (Lepidoptera: Crambidae) , 2003 .

[11]  E. Ulian,et al.  A new approach for control of Diatraea saccharalis (Lepidoptera: Crambidae) through the expression of an insecticidal CryIa(b) protein in transgenic sugarcane. , 2001 .

[12]  K. Fukui,et al.  Quantitative chromosome map of the polyploid Saccharum spontaneum by multicolor fluorescence in situ hybridization and imaging methods , 1999, Plant Molecular Biology.

[13]  J. Glaszmann,et al.  Oligoclonal interspecific origin of ‘North Indian’ and ‘Chinese’ sugarcanes , 2004, Chromosome Research.

[14]  The Biology of the Saccharum spp. (Sugarcane) , 2008 .

[15]  D. J. Heinz,et al.  Chapter 8 - Hybridization Procedures , 1987 .

[16]  P. Hooykaas Transformation Mediated by Agrobacterium tumefaciens , 2004 .

[17]  M. Manickavasagam,et al.  Agrobacterium-mediated genetic transformation and development of herbicide-resistant sugarcane (Saccharum species hybrids) using axillary buds , 2004, Plant Cell Reports.

[18]  D. Hogarth Genetics of Sugarcane , 1987 .

[19]  M. Araújo,et al.  Efeito da queima da palhada de cana-de-açúcar sobre comunidade de formicídeos , 2004 .

[20]  N. Islam-Faridi,et al.  Identification and characterisation of sugarcane intergeneric hybrids, Saccharum officinarum x Erianthus arundinaceus, with molecular markers and DNA in situ hybridisation , 1995, Theoretical and Applied Genetics.

[21]  P. Joyce,et al.  Engineering for resistance to SCMV in sugarcane , 1998 .

[22]  J. Glaszmann,et al.  A Review of Recent Molecular Genetics Evidence for Sugarcane Evolution and Domestication , 2004 .

[23]  W. J. Moore The role of sugar in the aetiology of dental caries. 1. Sugar and the antiquity of dental caries. , 1983, Journal of dentistry.

[24]  R. Coleman Physiology of flowering in sugarcane. , 1969 .

[25]  H. H. Haines The botany of Bihar and Orissa. , 1922 .

[26]  P. Arruda,et al.  The libraries that made SUCEST , 2001 .

[27]  Seshagiri Rao,et al.  Characterisation of the double genome structure of modern sugarcane cultivars ( , 1996 .

[28]  P. Arruda,et al.  Evolution of the Genes Encoding Seed Storage Proteins in Sugarcane and Maize , 2008, Tropical Plant Biology.

[29]  J. R. Wilson,et al.  New technologies for sugar milling and by-product modification. , 1997 .

[30]  J. Glaszmann,et al.  Characterisation of the double genome structure of modern sugarcane cultivars (Saccharum spp.) by molecular cytogenetics , 1996, Molecular and General Genetics MGG.

[31]  L. Autrey,et al.  CHAPTER II – Gumming disease , 1989 .

[32]  R. D. Webster,et al.  TAXONOMY OF THE NATIVE NORTH AMERICAN SPECIES OF SACCHARUM (POACEAE: ANDROPOGONEAE) , 1995 .

[33]  Hugo Bruno Correa Molinari,et al.  Evaluation of the stress-inducible production of proline in transgenic sugarcane (Saccharum spp.): osmotic adjustment, chlorophyll fluorescence and oxidative stress , 2007 .

[34]  M. Vincentz,et al.  Sugarcane: a major source of sweetness, alcohol, and bio-energy. , 2008 .

[35]  C. V. Dillewijn Botany of sugar cane. , 1960 .

[36]  B. Howard,et al.  Sugar and Cardiovascular Disease A Statement for Healthcare Professionals From the Committee on Nutrition of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association , 2002 .

[37]  M. L. C. Ripoli,et al.  Sistemas de Colheita , 2008 .

[38]  R. Wing,et al.  A bacterial artificial chromosome library for sugarcane , 1999, Theoretical and Applied Genetics.

[39]  R. Darke The Color Encyclopedia of Ornamental Grasses : Sedges, Rushes, Restios, Cat-Tails and Selected Bamboos , 1999 .

[40]  N. Balasundaram,et al.  On the Taxonomy of the Members of ‘Saccharum Complex’ , 2006, Genetic Resources and Crop Evolution.

[41]  R. Schmid,et al.  World Weeds: Natural Histories and Distribution , 1997 .

[42]  M. Chan,et al.  An efficient protocol for sugarcane (Saccharum spp. L.) transformation mediated by Agrobacterium tumefaciens , 1998, Transgenic Research.

[43]  A. Shelton,et al.  Assessment of risk of insect-resistant transgenic crops to nontarget arthropods , 2008, Nature Biotechnology.

[44]  A. D'Hont,et al.  Unraveling the genome structure of polyploids using FISH and GISH; examples of sugarcane and banana , 2005, Cytogenetic and Genome Research.

[45]  P. Moore,et al.  Chapter 7 - Flowering and Flower Synchronization , 1987 .

[46]  C. Grof,et al.  Agrobacterium-mediated transformation of sugarcane using GFP as a screenable marker , 1998 .

[47]  C. R. Soccol,et al.  AVALIAÇÃO MICROBIOLÓGICA DO CALDO DE CANA (GARAPA) NA CIDADE DE CURITIBA , 1990 .

[48]  P. Besse,et al.  Characterisation of Erianthus sect. Ripidium and Saccharum germplasm (Andropogoneae - Saccharinae) using RFLP markers , 1997, Euphytica.

[49]  J. M. Paturau,et al.  By-Products of the Cane Sugar Industry: An Introduction to their Industrial Utilization , 1969 .

[50]  C. O. Grassl Saccharum robustum and Other Wild Relatives of "Noble" Sugar Canes , 1946, Journal of the Arnold Arboretum.

[51]  N. Bor Grasses of Burma, Ceylon, India and Pakistan. , 1961 .

[52]  R. Henry,et al.  Domestication to Crop Improvement: Genetic Resources for Sorghum and Saccharum (Andropogoneae) , 2007, Annals of botany.

[53]  C. Ricaud,et al.  CHAPTER III – Leaf scald , 1989 .

[54]  G. A. de la Riva,et al.  Herbicide-resistant sugarcane (Saccharum officinarum L.) plants by Agrobacterium-mediated transformation , 1998, Planta.

[55]  R. P. Randall,et al.  A Global Compendium of Weeds , 2002 .

[56]  R. Birch,et al.  Transgenic sugarcane plants via microprojectile bombardment , 1992 .

[57]  N. Berding Improved Flowering and Pollen Fertility in Sugarcane under Increased Night Temperatures1 , 1981 .

[58]  R. S. Romeira Doencas causadas por bacterias em alho , 1995 .

[59]  J. Irvine,et al.  Herbicide Resistant Transgenic Sugarcane Plants Containing the bar Gene , 1996 .

[60]  S. B. Milligan Intensive Sugarcane Production: Meeting the Challenges Beyond 2000. Proceedings of the Sugar 2000 Symposium, Brisbane, Australia, 20–23 August 199 , 1998 .

[61]  D. J. Heinz,et al.  Sugarcane improvement through breeding , 1987 .

[62]  W. H. Longley Taxonomy and Evolution , 1933, Nature.

[63]  P. Moore,et al.  Prevention of flowering and increasing sugar yield of sugarcane by application of ethephon (2-chloroethylphosphonic acid) , 1989, Journal of Plant Growth Regulation.

[64]  R. Guedes,et al.  Impacto da queima controlada da palhada da cana-de-açúcar sobre a comunidade de insetos locais , 2005 .

[65]  R. Birch,et al.  High-efficiency, microprojectile-mediated cotransformation of sugarcane, using visible or selectable markers , 2004, Molecular Breeding.

[66]  S. Renvoize The grasses of Bahia. , 1984 .

[67]  J. Villaseñor,et al.  The alien flowering plants of Mexico , 2004 .

[68]  C. Daniels,et al.  The Geographical, Historical, and Cultural Aspects of the Origin of Indian and Chinese Sugarcanes, S. barberi and S. sinense , 1975 .

[69]  E. Ulian,et al.  Transformation and expression of a gene for herbicide resistance in a Brazilian sugarcane , 2000, Plant Cell Reports.

[70]  J. Irvine Saccharum species as horticultural classes , 1999, Theoretical and Applied Genetics.

[71]  N. Macedo,et al.  CONTROLE BIOLÓGICO Efeitos da Queima do Canavial sobre Parasitóides de Larvas e de Ovos de Diatraea saccharalis (Fabr.) (Lepidoptera: Crambidae) , 2000 .

[72]  P. Moore Anatomy and Morphology , 1987 .

[73]  B. Sobral,et al.  Comparative mapping of Andropogoneae: Saccharum L. (sugarcane) and its relation to sorghum and maize. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[74]  Lilian Eggers,et al.  Poaceae na área do Centro de Pesquisas e Conservação da Natureza Pró-Mata, São Francisco de Paula, Rio Grande do Sul, Brasil , 2005 .

[75]  J. Daniels,et al.  Taxonomy and Evolution , 1987 .

[76]  J. Murray,et al.  The role of sugar in the aetiology of dental caries. 2. The epidemiological evidence. , 1983, Journal of dentistry.

[77]  Eudes de Souza Leão Pinto Cana-de-açúcar , 1965 .

[78]  Antonella Zanobetti,et al.  The Impact of Sugar Cane–Burning Emissions on the Respiratory System of Children and the Elderly , 2006, Environmental health perspectives.

[79]  John F. Loutit Cytogenetics , 1967 .

[80]  Luguang Wu,et al.  Doubled sugar content in sugarcane plants modified to produce a sucrose isomer. , 2007, Plant biotechnology journal.

[81]  B. Sobral,et al.  Phylogenetic analysis of organellar DNA sequences in the Andropogoneae: Saccharinae , 1994, Theoretical and Applied Genetics.

[82]  S. Mukherjee Origin and Distribution of Saccharum , 1957, Botanical Gazette.

[83]  F. Botha,et al.  Preliminary analysis of expressed sequence tags for sugarcane. , 2000 .

[84]  A. S. Hitchcock Manual of the grasses of the United States , 1935 .

[85]  N. Macedo,et al.  Efeitos da queima do canavial sobre insetos predadores , 2000 .

[86]  R. Birch,et al.  Transformation of Sugarcane , 1993 .

[87]  N. Berding,et al.  Identifying the Risks of Transgene Escape from Sugarcane Crops to Related Species, with Particular Reference to Saccharum spontaneum in Australia , 2008, Tropical Plant Biology.

[88]  J. Wylie-Rosett,et al.  Sugar and Cardiovascular Disease , 2002 .

[89]  Mapeamento de potenciais de impactos ambientais da queima de cana-de-açúcar no Brasil , 2005 .

[90]  G. Smith,et al.  Cytokinin-enhanced regeneration of plants from microprojectile bombarded sugarcane meristematic tissue , 1994 .

[91]  J. Drenth,et al.  Genetic and expression profiling in sugarcane , 2001 .

[92]  D. Midmore Effects of photoperiod on flowering and fertility of sugarcane (Saccharum spp.). , 1980 .

[93]  R. Cesnik Melhoramento da cana-de-açúcar: marco sucro-alcooleiro no Brasil. , 2007 .

[94]  D. J. Heinz,et al.  Chapter 5 – Cytogenetics , 1987 .

[95]  R. Henry,et al.  Sugarcane microsatellites for the assessment of genetic diversity in sugarcane germplasm , 2003 .

[96]  Fei-Hu Liu,et al.  Expression of the Grifola frondosa Trehalose Synthase Gene and Improvement of Drought-Tolerance in Sugarcane (Saccharum officinarum L.) , 2006 .

[97]  J. Power,et al.  Transformation of sugarcane protoplasts by direct uptake of a selectable chimaeric gene , 1987, Plant Cell Reports.

[98]  H. Lorenzi Plantas daninhas do Brasil : terrestres, aquáticas, parasitas e tóxicas , 2000 .

[99]  David C. Ison,et al.  Determination of basic chromosome numbers in the genus Saccharum by physical mapping of ribosomal RNA genes , 1998 .

[100]  J. Harborne,et al.  The taxonomic significance of leaf flavonoids in Saccharum and related genera , 1974 .