Microencapsulation of cells, including islets, within stable ultra-thin membranes of maleimide-conjugated PEG-lipid with multifunctional crosslinkers.

[1]  John D Lambris,et al.  Autoregulation of thromboinflammation on biomaterial surfaces by a multicomponent therapeutic coating , 2012, Biomaterials.

[2]  W. Cui,et al.  Ultrathin Polymeric Coatings Based on Hydrogen‐Bonded Polyphenol for Protection of Pancreatic Islet Cells , 2012, Advanced functional materials.

[3]  B. Nilsson,et al.  Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood? , 2012, Stem cells.

[4]  J. C. Pickup,et al.  Nano-scale encapsulation enhances allograft survival and function of islets transplanted in a mouse model of diabetes , 2012, Diabetologia.

[5]  H. Iwata,et al.  Immobilization of soluble complement receptor 1 on islets. , 2011, Biomaterials.

[6]  U. Haglund,et al.  The Instant Blood-Mediated Inflammatory Reaction Characterized in Hepatocyte Transplantation , 2011, Transplantation.

[7]  H. Iwata,et al.  Co-immobilization of urokinase and thrombomodulin on islet surfaces by poly(ethylene glycol)-conjugated phospholipid. , 2011, Journal of controlled release : official journal of the Controlled Release Society.

[8]  H. Iwata,et al.  Improvement of Graft Survival by Surface Modification With Poly(ethylene glycol)-Lipid and Urokinase in Intraportal Islet Transplantation , 2011, Transplantation.

[9]  Hiroo Iwata,et al.  Bioartificial pancreas microencapsulation and conformal coating of islet of Langerhans. , 2010, Advanced drug delivery reviews.

[10]  H. Iwata,et al.  Retention dynamics of amphiphilic polymers PEG-lipids and PVA-Alkyl on the cell surface. , 2010, ACS applied materials & interfaces.

[11]  H. Iwata,et al.  Cell surface modification with polymers for biomedical studies , 2010 .

[12]  T. V. van Gulik,et al.  Complement-Mediated Ischemia-Reperfusion Injury: Lessons Learned From Animal and Clinical Studies , 2009, Annals of surgery.

[13]  John D Lambris,et al.  Complement activation triggered by chondroitin sulfate released by thrombin receptor‐activated platelets , 2008, Journal of thrombosis and haemostasis : JTH.

[14]  H. Iwata,et al.  Islets surface modification prevents blood-mediated inflammatory responses. , 2008, Bioconjugate chemistry.

[15]  H. Iwata,et al.  Behavior of synthetic polymers immobilized on a cell membrane. , 2008, Biomaterials.

[16]  J. Permert,et al.  Optimising islet engraftment is critical for successful clinical islet transplantation , 2008, Diabetologia.

[17]  E. Chaikof,et al.  Challenges and emerging technologies in the immunoisolation of cells and tissues. , 2008, Advanced drug delivery reviews.

[18]  T. Ichisaka,et al.  Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.

[19]  H. Iwata,et al.  Islet-encapsulation in ultra-thin layer-by-layer membranes of poly(vinyl alcohol) anchored to poly(ethylene glycol)-lipids in the cell membrane. , 2007, Biomaterials.

[20]  E. Chaikof,et al.  Surface re-engineering of pancreatic islets with recombinant azido-thrombomodulin. , 2007, Bioconjugate chemistry.

[21]  R. Larsson,et al.  Islet Surface Heparinization Prevents the Instant Blood-Mediated Inflammatory Reaction in Islet Transplantation , 2007, Diabetes.

[22]  Nalinkanth G. Veerabadran,et al.  Nanoencapsulation of stem cells within polyelectrolyte multilayer shells. , 2007, Macromolecular bioscience.

[23]  John D Lambris,et al.  Complement and coagulation: strangers or partners in crime? , 2007, Trends in immunology.

[24]  H. Iwata,et al.  Encapsulation of islets with ultra-thin polyion complex membrane through poly(ethylene glycol)-phospholipids anchored to cell membrane. , 2006, Biomaterials.

[25]  A. Gliozzi,et al.  Multilayer nanoencapsulation. New approach for immune protection of human pancreatic islets. , 2006, Nano letters.

[26]  Dong Yun Lee,et al.  Minimization of Immunosuppressive Therapy After Islet Transplantation: Combined Action of Heme Oxygenase‐1 and PEGylation to Islet , 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[27]  A. Narang,et al.  Biological and Biomaterial Approaches for Improved Islet Transplantation , 2006, Pharmacological Reviews.

[28]  A. Gliozzi,et al.  Interaction of polyelectrolytes and their composites with living cells. , 2005, Nano letters.

[29]  B. Manjula,et al.  Surface decoration of red blood cells with maleimidophenyl‐polyethylene glycol facilitated by thiolation with iminothiolane: an approach to mask A, B, and D antigens to generate universal red blood cells , 2005, Transfusion.

[30]  J. Contreras,et al.  A novel approach to xenotransplantation combining surface engineering and genetic modification of isolated adult porcine islets. , 2004 .

[31]  K. Ekdahl,et al.  Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation , 2002, The Lancet.

[32]  J F Elliott,et al.  Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. , 2001, Diabetes.

[33]  E. Ryan,et al.  Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. , 2000, The New England journal of medicine.

[34]  S. Takeoka,et al.  Poly(ethylene glycol)-modification of the phospholipid vesicles by using the spontaneous incorporation of poly(ethylene glycol)-lipid into the vesicles. , 2000, Bioconjugate chemistry.

[35]  G. Elgue,et al.  Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin. , 2000, Transplantation.

[36]  G. Elgue,et al.  Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation? , 1999, Diabetes.

[37]  P. Brunetti,et al.  Transplantation of Pancreatic Islets Contained in Minimal Volume Microcapsules in Diabetic High Mammalians , 1999, Annals of the New York Academy of Sciences.

[38]  B. Nilsson,et al.  A new in vitro model to study interaction between whole blood and biomaterials. Studies of platelet and coagulation activation and the effect of aspirin. , 1999, Biomaterials.

[39]  G. Keller,et al.  Human embryonic stem cells: The future is now , 1999, Nature Medicine.

[40]  H. Amemiya,et al.  Feasibility of agarose microbeads with xenogeneic islets as a bioartificial pancreas. , 1994, Journal of biomedical materials research.

[41]  T Akutsu,et al.  Agarose for a bioartificial pancreas. , 1992, Journal of biomedical materials research.

[42]  B. Nilsson,et al.  Generation of iC3 at the Interface between Blood and Gas , 1992, Scandinavian journal of immunology.

[43]  B. Nilsson,et al.  Simplified assays of hemolytic activity of the classical and alternative complement pathways. , 1984, Journal of immunological methods.

[44]  F. Lim,et al.  Microencapsulated islets as bioartificial endocrine pancreas. , 1980, Science.

[45]  T. Platts-Mills,et al.  Activation of the alternate pathway of human complements by rabbit cells. , 1974, Journal of immunology.

[46]  S. Moskalewski ISOLATION AND CULTURE OF THE ISLETS OF LANGERHANS OF THE GUINEA PIG. , 1965, General and comparative endocrinology.

[47]  John D Lambris,et al.  Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition? , 2010, Trends in immunology.