Enantioselective Synthesis of Boron‐Substituted Quaternary Carbons by NHC—Cu‐Catalyzed Boronate Conjugate Additions to Unsaturated Carboxylic Esters, Ketones, or Thioesters.
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A Cu-catalyzed method for enantioselective boronate conjugate additions to trisubstituted alkenes of acyclic α,β-unsaturated carboxylic esters, ketones, and thioesters is developed.
[1] A. Hoveyda,et al. Enantioselective synthesis of boron-substituted quaternary carbons by NHC-Cu-catalyzed boronate conjugate additions to unsaturated carboxylic esters, ketones, or thioesters. , 2010, Journal of the American Chemical Society.