Knowledge-based search for oncological literature

Using the current state of the art in life science publication search (e.g., PubMed), one can efficiently search for resources containing particular key-words or their combinations. It is impossible to search for abstract concepts and expressive relations between them (e.g., type of, different from or part of), though. Nevertheless, such a more expressive — semantic — search could largely reduce the efforts related to finding appropriate answers in biomedical articles. In this paper we identify challenges related to building a semantic publication search engine. Then we describe the architecture and usage principles of a tool tackling them. Eventually, we report on the tool's deployment on oncological literature data and preliminary tests with domain experts.

[1]  Dimitra Alexopoulou,et al.  GoPubMed: Exploring Pubmed with Ontological Background Knowledge , 2008, Ontologies and Text Mining for Life Sciences.

[2]  Vı́t Nováček,et al.  Towards an Efficient Knowledge-Based Publication Data Exploitation : An Oncological Literature Search Scenario , 2009 .

[3]  Carole A. Goble,et al.  State of the nation in data integration for bioinformatics , 2008, J. Biomed. Informatics.

[4]  Steffen Staab,et al.  Tackling the Ontology Acquisition Bottleneck: An Experiment in Ontology Re-Engineering , 2003 .

[5]  C. Fellbaum An Electronic Lexical Database , 1998 .

[6]  Steffen Staab,et al.  Discovering Conceptual Relations from Text , 2000, ECAI.

[7]  Steffen Staab,et al.  Learning Taxonomic Relations from Heterogeneous Sources of Evidence , 2005 .

[8]  Dan Brickley,et al.  Rdf vocabulary description language 1.0 : Rdf schema , 2004 .

[9]  C. K. Ogden,et al.  The Meaning of Meaning , 1923 .

[10]  Ronald R. Yager,et al.  On ordered weighted averaging aggregation operators in multicriteria decisionmaking , 1988, IEEE Trans. Syst. Man Cybern..

[11]  A. Greenwald 6 – Cognitive Learning, Cognitive Response to Persuasion, and Attitude Change1 , 1968 .

[12]  Mario Gómez,et al.  MELISA. An ontology-based agent for information retrieval in medicine , 2000 .

[13]  S. Griffis EDITOR , 1997, Journal of Navigation.

[14]  James A. Hendler,et al.  The Semantic Web" in Scientific American , 2001 .

[15]  Christiane Fellbaum,et al.  Book Reviews: WordNet: An Electronic Lexical Database , 1999, CL.

[16]  Siegfried Handschuh,et al.  KonneXSALT: First Steps Towards a Semantic Claim Federation Infrastructure , 2008, ESWC.

[17]  Chris Cornelis,et al.  On the representation of intuitionistic fuzzy t-norms and t-conorms , 2004, IEEE Transactions on Fuzzy Systems.

[18]  Hans-Michael Müller,et al.  Textpresso: An Ontology-Based Information Retrieval and Extraction System for Biological Literature , 2004, PLoS biology.

[19]  York Sure-Vetter,et al.  Learning Disjointness , 2007, ESWC.

[20]  Stefan Decker,et al.  Towards Lightweight and Robust Large Scale Emergent Knowledge Processing , 2009, International Semantic Web Conference.

[21]  Ronald R. Yager,et al.  On ordered weighted averaging aggregation operators in multicriteria decision-making , 1988 .

[22]  Diego Calvanese,et al.  The description logic handbook: theory , 2003 .