Analysis of Survival Among Adults With Early-Onset Colorectal Cancer in the National Cancer Database

This cohort study compares the survival among individuals with early-onset vs later-onset colorectal cancer using data from the US National Cancer Database.

[1]  Yuan-Bo Pan,et al.  Young-Onset Early Colorectal Cancer Had Similar Relative Survival to but Better Overall Survival Than Conventional Early Colorectal Cancer: A Large Population-Based Study , 2020, Frontiers in Oncology.

[2]  P. Buckhaults,et al.  Early-onset colorectal cancer: initial clues and current views , 2020, Nature Reviews Gastroenterology & Hepatology.

[3]  D. Ahnen,et al.  Trends in Incidence of Early-Onset Colorectal Cancer in the United States Among Those Approaching Screening Age , 2020, JAMA network open.

[4]  E. Stoffel,et al.  Epidemiology and Mechanisms of the Increasing Incidence of Colon and Rectal Cancers in Young Adults. , 2020, Gastroenterology.

[5]  Jeffrey S. Morris,et al.  Clinical and molecular characterization of early‐onset colorectal cancer , 2019, Cancer.

[6]  A. Bardelli,et al.  Early‐onset colorectal cancer in young individuals , 2018, Molecular oncology.

[7]  C. Allegra,et al.  Rectal cancer patients younger than 50 years lack a survival benefit from NCCN guideline–directed treatment for stage II and III disease , 2018, Cancer.

[8]  D. Boffa,et al.  Using the National Cancer Database for Outcomes Research: A Review , 2017, JAMA oncology.

[9]  David Lieberman,et al.  Colorectal Cancer Screening: Recommendations for Physicians and Patients From the U.S. Multi-Society Task Force on Colorectal Cancer. , 2017, Gastroenterology.

[10]  J. Marshall,et al.  The Growing Challenge of Young Adults With Colorectal Cancer. , 2017, Oncology.

[11]  K. McGlynn,et al.  Chemotherapy Use and Survival Among Young and Middle-Aged Patients With Colon Cancer , 2017, JAMA surgery.

[12]  A. Bhandari,et al.  Colorectal cancer is a leading cause of cancer incidence and mortality among adults younger than 50 years in the USA: a SEER-based analysis with comparison to other young-onset cancers , 2016, Journal of Investigative Medicine.

[13]  Z. Zeng,et al.  Colorectal cancer in the very young: a comparative study of tumor markers, pathology and survival in early onset and adult onset patients. , 2016, Journal of pediatric surgery.

[14]  M. Phipps,et al.  Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. , 2016, JAMA.

[15]  S. Hendren,et al.  Colorectal cancer outcomes and treatment patterns in patients too young for average‐risk screening , 2016, Cancer.

[16]  J. Pitkäniemi,et al.  Impact of Screening on Survival in Familial Adenomatous Polyposis , 2016, Journal of clinical gastroenterology.

[17]  S. Maithel,et al.  Clinicopathologic Features and Outcome of Young Adults With Stage IV Colorectal Cancer , 2015, American journal of clinical oncology.

[18]  Jeffrey S. Morris,et al.  The Consensus Molecular Subtypes of Colorectal Cancer , 2015, Nature Medicine.

[19]  T. Wilt,et al.  Screening for cancer: advice for high-value care from the American College of Physicians. , 2015, Annals of internal medicine.

[20]  J. Skibber,et al.  Overtreatment of young adults with colon cancer: more intense treatments with unmatched survival gains. , 2015, JAMA surgery.

[21]  D. Sargent,et al.  Association of age with survival in patients with metastatic colorectal cancer: analysis from the ARCAD Clinical Trials Program. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[22]  David M. Thomas,et al.  Benefits and adverse events in younger versus older patients receiving adjuvant chemotherapy for colon cancer: findings from the Adjuvant Colon Cancer Endpoints data set. , 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  David M. Thomas,et al.  Impact of young age on treatment efficacy and safety in advanced colorectal cancer: a pooled analysis of patients from nine first-line phase III chemotherapy trials. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[24]  Laetitia Huiart,et al.  Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome. , 2011, JAMA.

[25]  L. Boardman,et al.  Young-Onset Rectal Cancer: Presentation, Pattern of Care and Long-term Oncologic Outcomes Compared to a Matched Older-Onset Cohort , 2011, Annals of Surgical Oncology.

[26]  C. Compton,et al.  The American Joint Committee on Cancer: the 7th Edition of the AJCC Cancer Staging Manual and the Future of TNM , 2010, Annals of Surgical Oncology.

[27]  A. Ferrari,et al.  Distinct features of colorectal cancer in children and adolescents , 2010, Cancer.

[28]  Douglas K Rex,et al.  American College of Gastroenterology Guidelines for Colorectal Cancer Screening 2008 , 2022 .

[29]  Bernadette Mazurek Melnyk,et al.  Screening for colorectal cancer: U.S. Preventive Services Task Force recommendation statement. , 2008, Annals of internal medicine.

[30]  V. Stigliano,et al.  Journal of Experimental & Clinical Cancer Research Survival of Hereditary Non-polyposis Colorectal Cancer Patients Compared with Sporadic Colorectal Cancer Patients , 2008 .

[31]  Eero Pukkala,et al.  Cancer risk in hereditary nonpolyposis colorectal cancer syndrome: later age of onset. , 2005, Gastroenterology.

[32]  R. Houlston,et al.  Systematic review of microsatellite instability and colorectal cancer prognosis. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[33]  E. Livingston,et al.  Do Young Colon Cancer Patients Have Worse Outcomes? , 2004, World Journal of Surgery.

[34]  S. Bülow,et al.  Results of national registration of familial adenomatous polyposis , 2003, Gut.

[35]  U. P. S. T. Force,et al.  Screening for Colorectal Cancer: Recommendation and Rationale , 2002, Annals of Internal Medicine.

[36]  A. Sonnenberg,et al.  Colorectal cancer prevention 2000: screening recommendations of the American College of Gastroenterology , 2000, American Journal of Gastroenterology.

[37]  J. P. Dunn Colorectal cancer screening. , 1997, The New Zealand medical journal.

[38]  R. Simon,et al.  Flexible regression models with cubic splines. , 1989, Statistics in medicine.

[39]  David A. Schoenfeld,et al.  Partial residuals for the proportional hazards regression model , 1982 .

[40]  Patricia L. Smith Splines as a Useful and Convenient Statistical Tool , 1979 .

[41]  N. Breslow Covariance analysis of censored survival data. , 1974, Biometrics.

[42]  J. Peto,et al.  Asymptotically Efficient Rank Invariant Test Procedures , 1972 .

[43]  E. Kaplan,et al.  Nonparametric Estimation from Incomplete Observations , 1958 .

[44]  W. G. Cochran The $\chi^2$ Test of Goodness of Fit , 1952 .

[45]  H. B. Mann,et al.  On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other , 1947 .

[46]  D.,et al.  Regression Models and Life-Tables , 2022 .