Thrombin/inflammation paradigms: a closer look at arterial and venous thrombosis.

[1]  Z. Galis,et al.  Compensatory Vascular Remodeling During Atherosclerotic Lesion Growth Depends on Matrix Metalloproteinase-9 Activity , 2004 .

[2]  S. Narumiya,et al.  Roles of thromboxane A2 and prostacyclin in the development of atherosclerosis in apoE-deficient mice , 2004 .

[3]  E. Fisher,et al.  Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[4]  D. Broide,et al.  IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. , 2004, The Journal of clinical investigation.

[5]  Z. Galis Vulnerable plaque: the devil is in the details. , 2004, Circulation.

[6]  V. Fuster,et al.  Atherothrombosis: a widespread disease with unpredictable and life-threatening consequences. , 2004, European heart journal.

[7]  P. Ganz,et al.  Role of Endothelial Dysfunction in Atherosclerosis , 2004, Circulation.

[8]  T. van der Poll,et al.  Bidirectional Relation Between Inflammation and Coagulation , 2004, Circulation.

[9]  Antonio Colombo,et al.  Terminology for high-risk and vulnerable coronary artery plaques. Report of a meeting on the vulnerable plaque, June 17 and 18, 2003, Santorini, Greece. , 2004, European heart journal.

[10]  P. Libby,et al.  Inflammation, Immunity, and HMG-CoA Reductase Inhibitors: Statins as Antiinflammatory Agents? , 2004, Circulation.

[11]  Eric M Isselbacher,et al.  Atherosclerotic Vascular Disease Conference: Writing Group I: epidemiology. , 2004, Circulation.

[12]  A. Lusis,et al.  Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis. , 2004, The New England journal of medicine.

[13]  P. Libby,et al.  The vulnerable atherosclerotic plaque: pathogenesis and therapeutic approach. , 2004, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[14]  V. Fuster,et al.  Caspase-3 and Tissue Factor Expression in Lipid-Rich Plaque Macrophages: Evidence for Apoptosis as Link Between Inflammation and Atherothrombosis , 2004, Circulation.

[15]  E. Raines,et al.  Beyond the Endothelium: NF-&kgr;B Regulation of Smooth Muscle Function , 2004 .

[16]  P. Libby,et al.  Inflammation and atherosclerosis: role of C-reactive protein in risk assessment. , 2004, The American journal of medicine.

[17]  V. Fuster,et al.  Evolving Concepts in the Triad of Atherosclerosis, Inflammation and Thrombosis , 2004, Journal of Thrombosis and Thrombolysis.

[18]  Z. Galis,et al.  Matrix Metalloproteinase-2 and −9 Differentially Regulate Smooth Muscle Cell Migration and Cell-Mediated Collagen Organization , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[19]  P. Hordijk,et al.  Platelet-Monocyte Complexes Support Monocyte Adhesion to Endothelium by Enhancing Secondary Tethering and Cluster Formation , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[20]  Renu Virmani,et al.  Intraplaque hemorrhage and progression of coronary atheroma. , 2003, The New England journal of medicine.

[21]  C. Wiedermann,et al.  Syndecan-4-dependent signaling in the inhibition of endotoxin-induced endothelial adherence of neutrophils by antithrombin , 2003, Thrombosis and Haemostasis.

[22]  S. Shapiro Treating thrombosis in the 21st century. , 2003, The New England journal of medicine.

[23]  Georg Kraal,et al.  Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice. , 2003, The Journal of clinical investigation.

[24]  R. Tracy Thrombin, inflammation, and cardiovascular disease: an epidemiologic perspective. , 2003, Chest.

[25]  J. Badimón,et al.  Membrane-associated CD40L and sCD40L in atherothrombotic disease , 2003, Thrombosis and Haemostasis.

[26]  E. Falk,et al.  Pathology of coronary microembolisation and no reflow , 2003, Heart.

[27]  V. Fuster,et al.  Integration of vascular biology and magnetic resonance imaging in the understanding of atherothrombosis and acute coronary syndromes , 2003, Journal of thrombosis and haemostasis : JTH.

[28]  V. Fuster,et al.  Emerging importance of HDL cholesterol in developing high‐risk coronary plaques in acute coronary syndromes , 2003, Current opinion in cardiology.

[29]  P. Libby,et al.  Neutrophil Elastase in Human Atherosclerotic Plaques: Production by Macrophages , 2003, Circulation.

[30]  M. Gawaz,et al.  Activated platelets trigger an inflammatory response and enhance migration of aortic smooth muscle cells. , 2003, Thrombosis research.

[31]  V. Fuster,et al.  Is There a Vulnerable Plaque? , 2003, Circulation.

[32]  M. Prins,et al.  An association between atherosclerosis and venous thrombosis. , 2003, The New England journal of medicine.

[33]  James Scott ATVB In Focus , 2003 .

[34]  James Scott,et al.  ATVB In Focus: Lipoproteins, Inflammation, and Atherosclerosis , 2003 .

[35]  D. Granger,et al.  Hypercholesterolemia Promotes P-Selectin–Dependent Platelet–Endothelial Cell Adhesion in Postcapillary Venules , 2003, Arteriosclerosis, thrombosis, and vascular biology.

[36]  C. Heeschen,et al.  Soluble CD40 ligand in acute coronary syndromes. , 2003, The New England journal of medicine.

[37]  D. Phillips,et al.  Inhibitory Effects of Glycoprotein IIb/IIIa Antagonists and Aspirin on the Release of Soluble CD40 Ligand During Platelet Stimulation , 2003, Circulation.

[38]  V. Fuster,et al.  Role of Risk Factors in the Modulation of Tissue Factor Activity and Blood Thrombogenicity , 2003, Circulation.

[39]  M. Poncz,et al.  Platelet Factor 4 Enhances the Binding of Oxidized Low-density Lipoprotein to Vascular Wall Cells* , 2003, The Journal of Biological Chemistry.

[40]  S. Yusuf,et al.  Short- and long-term oral antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention. , 2003, Journal of the American College of Cardiology.

[41]  V. Fuster,et al.  Pathogenetic concepts of acute coronary syndromes. , 2003, Journal of the American College of Cardiology.

[42]  F. Ruschitzka,et al.  Selective COX-2 Inhibition Improves Endothelial Function in Coronary Artery Disease , 2003, Circulation.

[43]  U. Heinzmann,et al.  A Crucial Role of Glycoprotein VI for Platelet Recruitment to the Injured Arterial Wall In Vivo , 2003, The Journal of experimental medicine.

[44]  P. Libby Inflammation in atherosclerosis , 2002, Nature.

[45]  P. Shah,et al.  Increased Expression of Membrane Type 3-Matrix Metalloproteinase in Human Atherosclerotic Plaque: Role of Activated Macrophages and Inflammatory Cytokines , 2002, Circulation.

[46]  Zaverio M. Ruggeri,et al.  Platelets in atherothrombosis , 2002, Nature Medicine.

[47]  Z. Galis,et al.  Targeted Disruption of the Matrix Metalloproteinase-9 Gene Impairs Smooth Muscle Cell Migration and Geometrical Arterial Remodeling , 2002, Circulation research.

[48]  M. Gawaz,et al.  Engagement of Glycoprotein IIb/IIIa (&agr;IIb&bgr;3) on Platelets Upregulates CD40L and Triggers CD40L-Dependent Matrix Degradation by Endothelial Cells , 2002, Circulation.

[49]  K. Hatakeyama,et al.  Protease-activated receptor 2 (PAR2) mediates vascular smooth muscle cell migration induced by tissue factor/factor VIIa complex. , 2002, Thrombosis research.

[50]  P. Libby,et al.  Induction of Tissue Factor Expression in Human Endothelial Cells by CD40 Ligand Is Mediated via Activator Protein 1, Nuclear Factor κB, and Egr-1* , 2002, The Journal of Biological Chemistry.

[51]  D. Corella,et al.  Hyperlipidaemia and venous thromboembolism in patients lacking thrombophilic risk factors , 2002, British journal of haematology.

[52]  J. Vermylen,et al.  atherosclerosis-prone sites in response to hypercholesterolemia Endothelial von Willebrand factor recruits platelets to , 2013 .

[53]  G. D. De Meyer,et al.  Platelet Phagocytosis and Processing of &bgr;-Amyloid Precursor Protein as a Mechanism of Macrophage Activation in Atherosclerosis , 2002, Circulation research.

[54]  J. Heit Venous Thromboembolism Epidemiology: Implications for Prevention and Management , 2002, Seminars in thrombosis and hemostasis.

[55]  M. Poncz,et al.  Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic machinery, resulting in retention of low-density lipoprotein on the cell surface. , 2002, Blood.

[56]  F. Ruschitzka,et al.  High-Density Lipoprotein Restores Endothelial Function in Hypercholesterolemic Men , 2002, Circulation.

[57]  D. Harats,et al.  Patients With Glanzmann Thrombasthenia Lacking Platelet Glycoprotein αIIbβ3 (GPIIb/IIIa) and αvβ3 Receptors Are Not Protected From Atherosclerosis , 2002 .

[58]  R. Hynes,et al.  CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism , 2002, Nature Medicine.

[59]  Z. Galis,et al.  This Review Is Part of a Thematic Series on Matrix Metalloproteinases, Which Includes the following Articles: Matrix Metalloproteinase Inhibition after Myocardial Infarction: a New Approach to Prevent Heart Failure? Matrix Metalloproteinases in Vascular Remodeling and Atherogenesis: the Good, the Ba , 2022 .

[60]  A. Mattioli,et al.  Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients , 2002, BMJ : British Medical Journal.

[61]  Chun Yuan,et al.  Identification of Fibrous Cap Rupture With Magnetic Resonance Imaging Is Highly Associated With Recent Transient Ischemic Attack or Stroke , 2002, Circulation.

[62]  Catherine Sudlow,et al.  Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients , 2002, BMJ : British Medical Journal.

[63]  T. van der Poll,et al.  Regulatory role of cytokines in disseminated intravascular coagulation. , 2001, Seminars in thrombosis and hemostasis.

[64]  M. Peppelenbosch,et al.  The Pleiotropic Effects of Tissue Factor: a Possible Role for Factor VIIa-induced Intracellular Signalling? , 2001, Thrombosis and Haemostasis.

[65]  J. Badimón,et al.  Value or desirability of hemorheological-hemostatic parameter changes as endpoints in blood lipid-regulating trials , 2001, Current opinion in lipidology.

[66]  V. Fuster,et al.  Blood thrombogenicity in type 2 diabetes mellitus patients is associated with glycemic control. , 2001, Journal of the American College of Cardiology.

[67]  K. Ouriel Peripheral arterial disease , 2001, The Lancet.

[68]  L. Sharma,et al.  Leg symptoms in peripheral arterial disease: associated clinical characteristics and functional impairment. , 2001, JAMA.

[69]  R. Goldberg,et al.  Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction. , 2001, Journal of the American College of Cardiology.

[70]  M. Furman,et al.  Circulating Monocyte-Platelet Aggregates Are a More Sensitive Marker of In Vivo Platelet Activation Than Platelet Surface P-Selectin: Studies in Baboons, Human Coronary Intervention, and Human Acute Myocardial Infarction , 2001, Circulation.

[71]  Wei Huang,et al.  Role of thrombin signalling in platelets in haemostasis and thrombosis , 2001, Nature.

[72]  E. Falk,et al.  Plaque burden, arterial remodeling and plaque vulnerability: determined by systemic factors? , 2001, Journal of the American College of Cardiology.

[73]  C. Esmon,et al.  Down-regulation of endothelial expression of endothelial cell protein C receptor and thrombomodulin in coronary atherosclerosis. , 2001, The American journal of pathology.

[74]  D. Wagner,et al.  Localized reduction of atherosclerosis in von Willebrand factor-deficient mice. , 2001, Blood.

[75]  R. Kroczek,et al.  The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40. , 2001, Blood.

[76]  B. Sobel,et al.  Platelet Reactivity Characterized Prospectively: A Determinant of Outcome 90 Days After Percutaneous Coronary Intervention , 2001, Circulation.

[77]  A. Laupacis,et al.  Use of statins and the subsequent development of deep vein thrombosis. , 2001, Archives of internal medicine.

[78]  A. Tedgui,et al.  Current perspective on the role of apoptosis in atherothrombotic disease. , 2001, Circulation research.

[79]  J. Willerson,et al.  Local gene transfer of tissue factor pathway inhibitor regulates intimal hyperplasia in atherosclerotic arteries , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[80]  C. Esmon,et al.  Endothelial cell protein C receptor plays an important role in protein C activation in vivo. , 2001, Blood.

[81]  Valentin Fuster,et al.  Thrombus Formation on Atherosclerotic Plaques: Pathogenesis and Clinical Consequences , 2001, Annals of Internal Medicine.

[82]  M. Cybulsky,et al.  NF-κB: pivotal mediator or innocent bystander in atherogenesis? , 2001 .

[83]  V. Fuster,et al.  Inhibition of tissue factor reduces thrombus formation and intimal hyperplasia after porcine coronary angioplasty. , 2000, Journal of the American College of Cardiology.

[84]  V. Fuster,et al.  Statins and cardiovascular diseases: the multiple effects of lipid-lowering therapy by statins. , 2000, Atherosclerosis.

[85]  S. Coughlin,et al.  Thrombin signalling and protease-activated receptors , 2000, Nature.

[86]  Y. Nemerson,et al.  Circulating tissue factor and thrombosis , 2000, Current opinion in hematology.

[87]  V. Fuster,et al.  Increased thrombus formation relates to ambient blood glucose and leukocyte count in diabetes mellitus type 2. , 2000, The American journal of cardiology.

[88]  J. Badimón,et al.  Transfer of tissue factor from leukocytes to platelets is mediated by CD15 and tissue factor. , 2000, Blood.

[89]  P. Libby,et al.  Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[90]  T. Lüscher,et al.  The Beauty and the Beast: Aspects of the Autonomic Nervous System. , 2000, News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society.

[91]  V. Fuster,et al.  In vivo magnetic resonance evaluation of atherosclerotic plaques in the human thoracic aorta: a comparison with transesophageal echocardiography. , 2000, Circulation.

[92]  D. Wagner,et al.  Prominent role of P-selectin in the development of advanced atherosclerosis in ApoE-deficient mice. , 2000, Circulation.

[93]  R. Virmani,et al.  Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[94]  J. Badimón,et al.  Intimal Tissue Factor Activity Is Released from the Arterial Wall after Injury , 2000, Thrombosis and Haemostasis.

[95]  J. Freyssinet,et al.  Elevated levels of shed membrane microparticles with procoagulant potential in the peripheral circulating blood of patients with acute coronary syndromes. , 2000, Circulation.

[96]  T. van der Poll,et al.  Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia. , 2000, Blood.

[97]  E. Vittinghoff,et al.  Postmenopausal Hormone Therapy Increases Risk for Venous Thromboembolic Disease: The Heart and Estrogen/progestin Replacement Study , 2000, Annals of Internal Medicine.

[98]  D. Herrington,et al.  The Heart and Estrogen/Progestin Replacement Study , 1999, Drugs & aging.

[99]  P. Hutchinson,et al.  Tissue factor and factor VIIa receptor/ligand interactions induce proinflammatory effects in macrophages. , 1999, Blood.

[100]  F. Neumann,et al.  Effect of glycoprotein IIb/IIIa receptor blockade on platelet-leukocyte interaction and surface expression of the leukocyte integrin Mac-1 in acute myocardial infarction. , 1999, Journal of the American College of Cardiology.

[101]  K. Kugiyama,et al.  Heightened tissue factor associated with tissue factor pathway inhibitor and prognosis in patients with unstable angina. , 1999, Circulation.

[102]  G. Boden,et al.  Activation of the tissue factor pathway of blood coagulation during prolonged hyperglycemia in young healthy men. , 1999, Diabetes.

[103]  V. Fuster,et al.  Local inhibition of tissue factor reduces the thrombogenicity of disrupted human atherosclerotic plaques: effects of tissue factor pathway inhibitor on plaque thrombogenicity under flow conditions. , 1999, Circulation.

[104]  P. Meraj,et al.  Pravastatin therapy in hyperlipidemia: effects on thrombus formation and the systemic hemostatic profile. , 1999, Journal of the American College of Cardiology.

[105]  J. Badimón,et al.  Blood-borne tissue factor: another view of thrombosis. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[106]  J. Freyssinet,et al.  Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity. , 1999, Circulation.

[107]  G. D. De Meyer,et al.  Cell composition, replication, and apoptosis in atherosclerotic plaques after 6 months of cholesterol withdrawal. , 1998, Circulation research.

[108]  M. Winniford,et al.  Cigarette Smoking Increases Sympathetic Outflow in Humans , 1998 .

[109]  P. Libby,et al.  Reduction of atherosclerosis in mice by inhibition of CD40 signalling , 1998, Nature.

[110]  V. Fadok,et al.  The role of phosphatidylserine in recognition of apoptotic cells by phagocytes , 1998, Cell Death and Differentiation.

[111]  A. Herman,et al.  Apoptosis in atherogenesis: implications for plaque destabilization. , 1998, European heart journal.

[112]  R. Ross,et al.  Atherosclerosis is an inflammatory disease. , 1998, American heart journal.

[113]  Reinhold Förster,et al.  CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells , 1998, Nature.

[114]  K. Kaikita,et al.  Tissue factor expression on macrophages in coronary plaques in patients with unstable angina. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[115]  D. Lane,et al.  Thrombomodulin gene mutations associated with myocardial infarction. , 1997, Circulation.

[116]  M. Bennett,et al.  Thrombin generation by apoptotic vascular smooth muscle cells. , 1997, Blood.

[117]  W. Schaper,et al.  The role of Fas/APO 1 and apoptosis in the development of human atherosclerotic lesions. , 1997, Atherosclerosis.

[118]  G. Standen,et al.  Activated protein C resistance, factor V Leiden and peripheral vascular disease. , 1997, Cardiovascular surgery.

[119]  A. Karsan,et al.  Apoptotic vascular endothelial cells become procoagulant , 1997 .

[120]  T. Mayadas,et al.  Absence of P-selectin delays fatty streak formation in mice. , 1997, The Journal of clinical investigation.

[121]  J. Manson,et al.  A prospective study of risk factors for pulmonary embolism in women. , 1997, JAMA.

[122]  V. Fuster,et al.  Tissue factor modulates the thrombogenicity of human atherosclerotic plaques. , 1997, Circulation.

[123]  D. Green,et al.  Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl , 1995, The Journal of experimental medicine.

[124]  V. Fuster,et al.  Coronary plaque disruption. , 1995, Circulation.

[125]  E. Falk,et al.  Role of thrombosis in atherosclerosis and its complications. , 1995, The American journal of cardiology.

[126]  V. Fuster,et al.  Macrophage Infiltration in Acute Coronary Syndromes: Implications for Plaque Rupture , 1994, Circulation.

[127]  S Glagov,et al.  Intimal hyperplasia, vascular modeling, and the restenosis problem. , 1994, Circulation.

[128]  V. Fuster,et al.  Characterization of the relative thrombogenicity of atherosclerotic plaque components: implications for consequences of plaque rupture. , 1994, Journal of the American College of Cardiology.

[129]  S. Kimball,et al.  Regulation of hepatic protein synthesis in chronic inflammation and sepsis. , 1992, The American journal of physiology.

[130]  B. Smith,et al.  Dynamics of leukocyte-platelet adhesion in whole blood , 1991 .

[131]  M. Prins,et al.  A critical review of the evidence supporting a relationship between impaired fibrinolytic activity and venous thromboembolism. , 1991, Archives of internal medicine.

[132]  D. Ku,et al.  Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries. , 1988, Archives of pathology & laboratory medicine.

[133]  A. Chang,et al.  Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon. , 1987, The Journal of clinical investigation.

[134]  E. Falk Unstable angina with fatal outcome: dynamic coronary thrombosis leading to infarction and/or sudden death. Autopsy evidence of recurrent mural thrombosis with peripheral embolization culminating in total vascular occlusion. , 1985, Circulation.

[135]  R. Ross Platelets: cell proliferation and atherosclerosis. , 1979, Metabolism: clinical and experimental.

[136]  R. de Caterina,et al.  Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiology. , 2004, European heart journal.

[137]  J. Badimón,et al.  Atherothrombosis: the role of tissue factor. , 2004, The international journal of biochemistry & cell biology.

[138]  S. Coughlin,et al.  PARticipation in inflammation. , 2003, The Journal of clinical investigation.

[139]  Andreas Schober,et al.  Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E , 2003, Nature Medicine.

[140]  F. Rosendaal,et al.  D-Dimer as a Risk Factor for Deep Vein Thrombosis: The Leiden Thrombophilia Study , 2002, Thrombosis and Haemostasis.

[141]  B. Cosmi,et al.  Risk of Venous Thromboembolism Recurrence: High Negative Predictive Value of D-dimer Performed after Oral Anticoagulation Is Stopped , 2002, Thrombosis and Haemostasis.

[142]  P. Libby,et al.  CD40 ligation induces tissue factor expression in human vascular smooth muscle cells. , 2000, The American journal of pathology.

[143]  Aldons J. Lusis,et al.  Atherosclerosis : Vascular biology , 2000 .

[144]  R. Colman,et al.  The contact system contributes to hypotension but not disseminated intravascular coagulation in lethal bacteremia. In vivo use of a monoclonal anti-factor XII antibody to block contact activation in baboons. , 1993, The Journal of clinical investigation.

[145]  M. Davies,et al.  Atherosclerosis: what is it and why does it occur? , 1993, British heart journal.