14‐3‐3 Proteins fine‐tune plant nutrient metabolism

14‐3‐3 Proteins regulate many cellular processes by binding to phosphorylated proteins. Previous findings suggest a connection between three 14‐3‐3 isoforms and plant nutrient signaling. To better understand how these 14‐3‐3s regulate metabolism in response to changes in plant nutrient status, putative new targets involved in nitrogen (N) and sulfur (S) metabolisms have been identified. The interactions between these 14‐3‐3s and multiple proteins involved in N and S metabolism and altered activity of the target proteins were confirmed in planta. Using a combination of methods, this work elucidates how 14‐3‐3s function as modulators of plant N and S metabolic pathways.

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