A dedication in memoriam of Dr. Richard Skalak.

Richard Skalak (1923-1997) played a leadership role in the formative decades of the discipline of biomedical engineering through his technical contributions in biomechanics, his educational influence on students, and his service to many developing societies and journals. But always, the distinguishing marks of his involvement with any activity or person were his generosity, respect and tolerance for others, integrity, and curiosity. These very qualities are what first brought him as a traditional engineering trained in engineering mechanics into the young field of biomedical engineering in the 1960s, and they are what led him to new approaches to cellular and molecular engineering, tissue engineering, and orthopedic biomechanics. His technical papers and lectures on blood cell mechanics, pulmonary circulation, dental implants, and tissue growth were models of clarity and often pointed the way to new areas of exploration, while his personal writings offer advice on life, academic organizations, and the pursuit of significant work. He would be deeply appreciative that this first volume of the Annual Review of Biomedical Engineering is dedicated to his memory.

[1]  F Wiener,et al.  Wave Propagation in the Pulmonary Circulation , 1966, Circulation research.

[2]  R Skalak,et al.  Biomechanical considerations in osseointegrated prostheses. , 1983, The Journal of prosthetic dentistry.

[3]  R. Skalak,et al.  Passive mechanical properties of human leukocytes. , 1981, Biophysical journal.

[4]  M Sugihara-Seki,et al.  Asymmetric flows of spherical particles in a cylindrical tube. , 1997, Biorheology.

[5]  S Chien,et al.  Effect of hematocrit and rouleaux on apparent viscosity in capillaries. , 1972, Biorheology.

[6]  R. Skalak,et al.  Time-dependent behavior of interstitial fluid pressure in solid tumors: implications for drug delivery. , 1995, Cancer research.

[7]  R. Skalak,et al.  Deformation of Red Blood Cells in Capillaries , 1969, Science.

[8]  S Chien,et al.  Spectrin properties and the elasticity of the red blood cell membrane skeleton. , 1997, Biorheology.

[9]  R Skalak,et al.  The motion of close-packed red blood cells in shear flow. , 1983, Biorheology.

[10]  R Skalak Poiseuille Medal lecture. Capillary flow: past, present, and future. , 1990, Biorheology.

[11]  S Chien,et al.  An elastic network model based on the structure of the red blood cell membrane skeleton. , 1996, Biophysical journal.

[12]  R Skalak,et al.  Passive deformations and active motions of leukocytes. , 1990, Journal of biomechanical engineering.

[13]  R. Skalak,et al.  Strain energy function of red blood cell membranes. , 1973, Biophysical journal.

[14]  R Skalak,et al.  One-dimensional steady continuum model of retraction of pseudopod in leukocytes. , 1989, Journal of biomechanical engineering.

[15]  Y. Fung,et al.  Biomechanics: Mechanical Properties of Living Tissues , 1981 .

[16]  Shu Chien,et al.  Handbook of Bioengineering , 1986 .

[17]  Rickard Brånemark,et al.  Biomechanical characterization of osseointegration: An experimental in vivo investigation in the beagle dog , 1998, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[18]  R. Skalak,et al.  Passive deformation analysis of human leukocytes. , 1988, Journal of biomechanical engineering.

[19]  S Chien,et al.  Elastic deformations of red blood cells. , 1977, Journal of biomechanics.

[20]  W. Kristan,et al.  A model of the hydrostatic skeleton of the leech. , 1996, Journal of theoretical biology.

[21]  S Chien,et al.  Shear stress induces spatial reorganization of the endothelial cell cytoskeleton. , 1998, Cell motility and the cytoskeleton.

[22]  Henry Wang,et al.  Viscous flow in a cylindrical tube containing a line of spherical particles , 1969, Journal of Fluid Mechanics.

[23]  R Skalak,et al.  A two-dimensional model for capillary flow of an asymmetric cell. , 1982, Microvascular research.

[24]  Richard Skalak,et al.  EXTENSIONS OF EXTREMUM PRINCIPLES FOR SLOW VISCOUS FLOWS. , 1970 .

[25]  Richard Skalak,et al.  Mechanisms for increased blood flow resistance due to leukocytes. , 1997, American journal of physiology. Heart and circulatory physiology.

[26]  E Otten,et al.  Analytical description of growth. , 1982, Journal of theoretical biology.