论文信息 - A polymorphic tetranucleotide repeat in the CYP19 gene and male breast cancer

A polymorphic tetranucleotide repeat in the CYP19 gene and male breast cancer

The CYP19 gene codes for the aromatase enzyme that is involved in the synthesis of oestrogens. This case–control study examines the relationship between a tetranucleotide repeat sequence in the CYP19 gene and the development of male breast cancer. No significant differences were found between male breast cancer cases and controls. © 2000 Cancer Research Campaign

[2] K. Buetow,et al. Constitutional genetic variation at the human aromatase gene (Cyp19) and breast cancer risk , 1999, British Journal of Cancer.

[3] A. Børresen-Dale,et al. A rare CYP19 (aromatase) variant may increase the risk of breast cancer. , 1998, Pharmacogenetics.

[4] S. Ueda,et al. Combined polymorphism associated with a 3-bp deletion in the 5'-flanking region of a tetrameric short tandem repeat at the CYP19 locus. , 1997, Nihon hoigaku zasshi = The Japanese journal of legal medicine.

[5] H. Sasano,et al. Aromatase and steroid receptors in gynecomastia and male breast carcinoma: an immunohistochemical study. , 1996, The Journal of clinical endocrinology and metabolism.

[6] M. H. Polymeropoulos,et al. Tetranucleotide repeat polymorphism at the human aromatase cytochrome P- 450 gene (CYP19) , 1991, Nucleic Acids Res..

[7] J. Mathis,et al. Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis. , 1989, The Journal of biological chemistry.

[8] C. H. Ockey,et al. Carcinoma of Male Breast in Association with the Klinefelter Syndrome , 1965, British medical journal.

[9] P. Winship,et al. POLYMORPHISM , 1945, Physics and Chemistry of Molecular Assemblies.