Photosensitizer-based small molecule theranostic agents for tumor-targeted monitoring and phototherapy.

[1]  M. Shiddiq,et al.  High Reactive Oxygen Species Produce from the Fluorescence Carbon Dots for Anticancer and Photodynamic Therapy: A. Review. , 2022, Luminescence : the journal of biological and chemical luminescence.

[2]  W. Zipfel,et al.  Two-Photon Photodynamic Therapy Targeting Cancers with Low Carboxylesterase 2 Activity Guided by Ratiometric Fluorescence. , 2022, Journal of medicinal chemistry.

[3]  Yanfang Zhao,et al.  Fibroblast activation protein α activatable theranostic pro-photosensitizer for accurate tumor imaging and highly-specific photodynamic therapy , 2022, Theranostics.

[4]  Yuncong Chen,et al.  Recent advances in noble metal complex based photodynamic therapy , 2022, Chemical science.

[5]  Q. Yao,et al.  Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook. , 2022, Chemical Society reviews.

[6]  S. Davaran,et al.  Recent Advances and Trends in Nanoparticles based Photothermal and Photodynamic Therapy. , 2021, Photodiagnosis and photodynamic therapy.

[7]  Hung-Yun Lin,et al.  Nano-Strategies Targeting the Integrin αvβ3 Network for Cancer Therapy , 2021, Cells.

[8]  S. Pengthaisong,et al.  Glucose conjugated aza-BODIPY for enhanced photodynamic cancer therapy. , 2021, Organic & biomolecular chemistry.

[9]  I. Tannock,et al.  The European Union and personalised cancer medicine. , 2021, European journal of cancer.

[10]  A. G. Robertson,et al.  Gadolinium theranostics for the diagnosis and treatment of cancer. , 2021, Chemical Society reviews.

[11]  L. Duan,et al.  Upconversion NIR-II fluorophores for mitochondria-targeted cancer imaging and photothermal therapy , 2020, Nature Communications.

[12]  Yongchang Wei,et al.  All-in-one mitochondria-targeted NIR-II fluorophores for cancer therapy and imaging , 2020, Chemical science.

[13]  E. Kuru,et al.  Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo , 2020, Nature Communications.

[14]  Jong Seung Kim,et al.  An Ethacrynic Acid-Brominated BODIPY Photosensitizer (EA-BPS) Construct Enhances the Lethality of Reactive Oxygen Species in Hypoxic Tumor-Targeted Photodynamic Therapy. , 2020, Angewandte Chemie.

[15]  N. Etienne-Selloum,et al.  Biological Relevance of RGD‐Integrin Subtype‐Specific Ligands in Cancer , 2020, Chembiochem : a European journal of chemical biology.

[16]  Caixia Yang,et al.  Facile one-pot synthesis of cyclic peptide-conjugated photosensitisers for targeted photodynamic therapy. , 2020, Chemical communications.

[17]  Yi Xie,et al.  A NIR-I light-responsive superoxide radical generator with cancer cell membrane targeting ability for enhanced imaging-guided photodynamic therapy† , 2020, Chemical science.

[18]  C. Printz.  Cancer screenings decline significantly during pandemic , 2020, Cancer.

[19]  Jianjun Du,et al.  A Single Molecule Drug Targeting Photosensitizer for Enhanced Breast Cancer Photothermal Therapy. , 2020, Small.

[20]  Hoon Hyun,et al.  Tumor-targeted near-infrared fluorophore for fluorescence-guided phototherapy. , 2020, Chemical communications.

[21]  Ming-Shan Zhang,et al.  A glutathione-responsive photosensitizer with fluorescence resonance energy transfer characteristics for imaging-guided targeting photodynamic therapy. , 2020, European journal of medicinal chemistry.

[22]  R. Hajjo,et al.  Review on Epidermal Growth Factor Receptor (EGFR) Structure, Signaling Pathways, Interactions, and Recent Updates of EGFR Inhibitors. , 2020, Current topics in medicinal chemistry.

[23]  Ji Hyeon Kim,et al.  Unimolecular Photodynamic O2-Economizer to Overcome Hypoxia Resistance in Phototherapeutics. , 2020, Journal of the American Chemical Society.

[24]  M. Calderón,et al.  pH Activatable Singlet Oxygen Generating Boron-dipyrromethenes (BODIPYs) for Photodynamic Therapy and Bioimaging. , 2020, Journal of medicinal chemistry.

[25]  J. Xue,et al.  An epidermal growth factor receptor-targeted and endoplasmic reticulum-localized organic photosensitizer toward photodynamic anticancer therapy. , 2019, European journal of medicinal chemistry.

[26]  Kibeom Kim,et al.  Mitochondrial heat shock protein-guided photodynamic therapy. , 2019, Chemical communications.

[27]  Ryan T. K. Kwok,et al.  Time-dependent Photodynamic Therapy for Multiple Targets: A Highly Efficient AIE-active Photosensitizer for Selective Bacterial Elimination and Cancer Cell Ablation. , 2019, Angewandte Chemie.

[28]  Saran Long,et al.  Development of a novel anti-tumor theranostic platform: a near-infrared molecular upconversion sensitizer for deep-seated cancer photodynamic therapy† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc04034j , 2019, Chemical science.

[29]  J. Zhao,et al.  Imaging Dynamic Peroxynitrite Fluxes in Epileptic Brains with a Near‐Infrared Fluorescent Probe , 2019, Advanced science.

[30]  K. Guru,et al.  Epidermal Growth Factor Receptor-Targeted Multifunctional Photosensitizers for Bladder Cancer Imaging and Photodynamic Therapy. , 2019, Journal of medicinal chemistry.

[31]  Na Li,et al.  A Dual-Targeted Organic Photothermal Agent for Enhanced Photothermal Therapy. , 2019, Angewandte Chemie.

[32]  Saran Long,et al.  Superoxide Radical Photogenerator with Amplification Effect: Surmounting the Achilles' Heels of Photodynamic Oncotherapy. , 2019, Journal of the American Chemical Society.

[33]  J. Xue,et al.  A novel tumor and mitochondria dual-targeted photosensitizer showing ultra-efficient photodynamic anticancer activities. , 2019, Chemical communications.

[34]  Saran Long,et al.  De Novo Design of Phototheranostic Sensitizers Based on Structure-Inherent Targeting for Enhanced Cancer Ablation. , 2018, Journal of the American Chemical Society.

[35]  Yang Liu,et al.  Light-activatable cannabinoid prodrug for combined and target-specific photodynamic and cannabinoid therapy , 2018, Journal of biomedical optics.

[36]  B. Tang,et al.  Highly Efficient Photosensitizers with Far‐Red/Near‐Infrared Aggregation‐Induced Emission for In Vitro and In Vivo Cancer Theranostics , 2018, Advanced materials.

[37]  Kenry,et al.  A Light-Up Probe with Aggregation-Induced Emission for Real-Time Bio-orthogonal Tumor Labeling and Image-Guided Photodynamic Therapy. , 2018, Angewandte Chemie.

[38]  Nicholas J Schork,et al.  Personalized medicine: motivation, challenges, and progress. , 2018, Fertility and sterility.

[39]  D. Ding,et al.  Enzyme-instructed self-assembly leads to the activation of optical properties for selective fluorescence detection and photodynamic ablation of cancer cells. , 2018, Journal of materials chemistry. B.

[40]  B. Liu,et al.  Artemisinin and AIEgen Conjugate for Mitochondria-Targeted and Image-Guided Chemo- and Photodynamic Cancer Cell Ablation. , 2018, ACS applied materials & interfaces.

[41]  Lintao Cai,et al.  Tumor-targeted small molecule for dual-modal imaging-guided phototherapy upon near-infrared excitation. , 2017, Journal of materials chemistry. B.

[42]  M. Kamal,et al.  Enzyme targeting strategies for prevention and treatment of cancer: Implications for cancer therapy. , 2017, Seminars in cancer biology.

[43]  Youyong Yuan,et al.  Smart activatable and traceable dual-prodrug for image-guided combination photodynamic and chemo-therapy. , 2017, Biomaterials.

[44]  T. Cheng,et al.  Structure‐Guided Design and Synthesis of a Mitochondria‐Targeting Near‐Infrared Fluorophore with Multimodal Therapeutic Activities , 2017, Advanced materials.

[45]  M. Kinch,et al.  2016 in review: FDA approvals of new molecular entities. , 2017, Drug discovery today.

[46]  Zhan Chen,et al.  Dual Channel Activatable Cyanine Dye for Mitochondrial Imaging and Mitochondria-Targeted Cancer Theranostics. , 2017, ACS biomaterials science & engineering.

[47]  Y. Urano,et al.  Development of an Azo-Based Photosensitizer Activated under Mild Hypoxia for Photodynamic Therapy. , 2017, Journal of the American Chemical Society.

[48]  Mako Kamiya,et al.  An Activatable Photosensitizer Targeted to γ-Glutamyltranspeptidase. , 2017, Angewandte Chemie.

[49]  T. Deng,et al.  Multifunctional Small Molecule Fluorophore for Long‐Duration Tumor‐Targeted Monitoring and Dual Modal Phototherapy , 2017 .

[50]  J. Buchner,et al.  The HSP90 chaperone machinery , 2017, Nature Reviews Molecular Cell Biology.

[51]  T. Jiang,et al.  Dual-Responsive Molecular Probe for Tumor Targeted Imaging and Photodynamic Therapy , 2017, Theranostics.

[52]  B. Tang,et al.  AIE-active theranostic system: selective staining and killing of cancer cells , 2016, Chemical science.

[53]  Xunbin Wei,et al.  Selective imaging and cancer cell death via pH switchable near-infrared fluorescence and photothermal effects† †Electronic supplementary information (ESI) available: Synthesis, characterization, experimental details and other figures and spectra. See DOI: 10.1039/c6sc00221h , 2016, Chemical science.

[54]  Shenglin Luo,et al.  Mitochondria‐Targeted Small‐Molecule Fluorophores for Dual Modal Cancer Phototherapy , 2016 .

[55]  Youyong Yuan,et al.  Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation. , 2016, Journal of materials chemistry. B.

[56]  Youyong Yuan,et al.  A self-reporting AIE probe with a built-in singlet oxygen sensor for targeted photodynamic ablation of cancer cells† †Electronic supplementary information (ESI) available: Synthesis and characterization of the intermediates; molecular orbital data. See DOI: 10.1039/c5sc03583j , 2015, Chemical science.

[57]  B. Tang,et al.  Light‐Up Probe for Targeted and Activatable Photodynamic Therapy with Real‐Time In Situ Reporting of Sensitizer Activation and Therapeutic Responses , 2015 .

[58]  Jong Seung Kim,et al.  Small conjugate-based theranostic agents: an encouraging approach for cancer therapy. , 2015, Chemical Society reviews.

[59]  Kai Gao,et al.  Hyperbaric oxygen promotes malignant glioma cell growth and inhibits cell apoptosis. , 2015, Oncology letters.

[60]  Ben Zhong Tang,et al.  Specific light-up bioprobe with aggregation-induced emission and activatable photoactivity for the targeted and image-guided photodynamic ablation of cancer cells. , 2015, Angewandte Chemie.

[61]  Jong-Hyeon Jeong,et al.  Trastuzumab plus adjuvant chemotherapy for human epidermal growth factor receptor 2-positive breast cancer: planned joint analysis of overall survival from NSABP B-31 and NCCTG N9831. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[62]  C. Tung,et al.  Smart dual-functional warhead for folate receptor-specific activatable imaging and photodynamic therapy. , 2014, Chemical communications.

[63]  Guanxin Zhang,et al.  Targeted bioimaging and photodynamic therapy of cancer cells with an activatable red fluorescent bioprobe. , 2014, Analytical chemistry.

[64]  Ji-yao Chen,et al.  Conjugates of folic acids with zinc aminophthalocyanine for cancer cell targeting and photodynamic therapy by one-photon and two-photon excitations. , 2014, Journal of materials chemistry. B.

[65]  Mei-Rong Ke,et al.  Preparation and in vitro photodynamic activities of folate-conjugated distyryl boron dipyrromethene based photosensitizers. , 2013, Journal of medicinal chemistry.

[66]  K. Burgess,et al.  Double-targeting using a TrkC ligand conjugated to dipyrrometheneboron difluoride (BODIPY) based photodynamic therapy (PDT) agent. , 2013, Journal of medicinal chemistry.

[67]  T. Cheng,et al.  A multifunctional heptamethine near-infrared dye for cancer theranosis. , 2013, Biomaterials.

[68]  Eunhwa Ko,et al.  Small Molecule Ligands For Active Targeting Of TrkC-expressing Tumor Cells. , 2012, ACS medicinal chemistry letters.

[69]  N. Demaurex,et al.  The renaissance of mitochondrial pH , 2012, The Journal of general physiology.

[70]  Shenglin Luo,et al.  A NIR heptamethine dye with intrinsic cancer targeting, imaging and photosensitizing properties. , 2012, Biomaterials.

[71]  Guido Kroemer,et al.  Lysosomes and autophagy in cell death control , 2005, Nature Reviews Cancer.

[72]  Timothy W Secomb,et al.  Synergistic effects of hyperoxic gas breathing and reduced oxygen consumption on tumor oxygenation: a theoretical model. , 2004, International journal of radiation oncology, biology, physics.

[73]  K. Pfizenmaier,et al.  Generation of human high-affinity antibodies specific for the fibroblast activation protein by guided selection. , 2001, European journal of biochemistry.

[74]  Bonnie F. Sloane,et al.  Fluorescent microplate assay for cancer cell-associated cathepsin B. , 2000, European journal of biochemistry.