The multifaceted mismatch-repair system
暂无分享,去创建一个
[1] G. Plotz,et al. Analysis of the human MutLα·MutSα complex , 2006 .
[2] P. Modrich,et al. Human Mismatch Repair , 2005, Journal of Biological Chemistry.
[3] S. Lipkin,et al. Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair. , 2005, Cancer research.
[4] S. Lipkin,et al. Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse. , 2005, Cancer research.
[5] A. Tomkinson,et al. Reconstitution of 5′-Directed Human Mismatch Repair in a Purified System , 2005, Cell.
[6] Ludovic C. Gillet,et al. Homologous Recombination Rescues Mismatch-Repair-Dependent Cytotoxicity of SN1-Type Methylating Agents in S. cerevisiae , 2005, Current Biology.
[7] Raju Kucherlapati,et al. (CAG)n-hairpin DNA binds to Msh2–Msh3 and changes properties of mismatch recognition , 2005, Nature Structural &Molecular Biology.
[8] J. Heierhorst,et al. ASCIZ regulates lesion‐specific Rad51 focus formation and apoptosis after methylating DNA damage , 2005, The EMBO journal.
[9] T. Kunkel,et al. DNA mismatch repair. , 2005, Annual review of biochemistry.
[10] Marc L. Mendillo,et al. Analysis of the Interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 Complexes with DNA Using a Reversible DNA End-blocking System* , 2005, Journal of Biological Chemistry.
[11] F. Yuan,et al. hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair , 2005, EMBO reports.
[12] Dong Wang,et al. Cellular processing of platinum anticancer drugs , 2005, Nature Reviews Drug Discovery.
[13] K. Brown,et al. Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2. , 2005, Molecular biology of the cell.
[14] A. Yasui,et al. MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A:T mutations in antibody genes , 2005, The Journal of experimental medicine.
[15] M. Goodman,et al. Identifying protein–protein interactions in somatic hypermutation , 2005, The Journal of experimental medicine.
[16] N. de Wind,et al. Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes. , 2005, DNA repair.
[17] L. Symington,et al. EXO1-A multi-tasking eukaryotic nuclease. , 2004, DNA repair.
[18] C. Kunz,et al. Meiotic Recombination: Sealing the Partnership at the Junction , 2004, Current Biology.
[19] M. Lamers,et al. ATP Increases the Affinity between MutS ATPase Domains , 2004, Journal of Biological Chemistry.
[20] Victor A Tron,et al. DNA mismatch repair proteins promote apoptosis and suppress tumorigenesis in response to UVB irradiation: an in vivo study. , 2004, Carcinogenesis.
[21] E. Hoffmann,et al. Meiotic recombination intermediates and mismatch repair proteins , 2004, Cytogenetic and Genome Research.
[22] Tao Yan,et al. CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses. , 2004, Molecular cancer therapeutics.
[23] P. G. Wells,et al. Antisense Evidence for Nuclear Factor-κB–Dependent Embryopathies Initiated by Phenytoin-Enhanced Oxidative Stress , 2004 .
[24] M. Berardini,et al. hMSH4-hMSH5 recognizes Holliday Junctions and forms a meiosis-specific sliding clamp that embraces homologous chromosomes. , 2004, Molecular cell.
[25] Mimi Y. Kim,et al. Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility. , 2004, Cancer cell.
[26] J. Jiricny,et al. Mismatch repair and DNA damage signalling. , 2004, DNA repair.
[27] Paul Modrich,et al. Differential Specificities and Simultaneous Occupancy of Human MutSα Nucleotide Binding Sites* , 2004, Journal of Biological Chemistry.
[28] P. Modrich,et al. A defined human system that supports bidirectional mismatch-provoked excision. , 2004, Molecular cell.
[29] S. Ferrari,et al. Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase. , 2004, Genes & development.
[30] T. Kinsella,et al. Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR-Chk1 pathway. , 2004, Biochemical and biophysical research communications.
[31] J. Hays,et al. Signaling from DNA mispairs to mismatch‐repair excision sites despite intervening blockades , 2004, The EMBO journal.
[32] J. Jiricny,et al. Dependence of the Cytotoxicity of DNA-Damaging Agents on the Mismatch Repair Status of Human Cells , 2004, Cancer Research.
[33] F. Yuan,et al. Evidence for Involvement of HMGB1 Protein in Human DNA Mismatch Repair* , 2004, Journal of Biological Chemistry.
[34] B. Kaina,et al. Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go , 2004, Cytogenetic and Genome Research.
[35] R. Kucherlapati,et al. An Msh2 Point Mutation Uncouples DNA Mismatch Repair and Apoptosis , 2004, Cancer Research.
[36] J. Qin,et al. MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[37] P. Modrich,et al. Mechanism of 5'-directed excision in human mismatch repair. , 2003, Molecular cell.
[38] J. Hays,et al. Mismatch Repair in Human Nuclear Extracts , 2003, Journal of Biological Chemistry.
[39] Richard Fishel,et al. The coordinated functions of the E. coli MutS and MutL proteins in mismatch repair. , 2003, Molecular cell.
[40] T. Kinsella,et al. DNA mismatch repair (MMR) mediates 6-thioguanine genotoxicity by introducing single-strand breaks to signal a G2-M arrest in MMR-proficient RKO cells. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[41] Reuben S Harris,et al. Immunity through DNA deamination. , 2003, Trends in biochemical sciences.
[42] M. Schofield,et al. Crystal Structure and Biochemical Analysis of the MutS·ADP·Beryllium Fluoride Complex Suggests a Conserved Mechanism for ATP Interactions in Mismatch Repair* 210 , 2003, The Journal of Biological Chemistry.
[43] J. Jiricny,et al. Methylation‐induced G2/M arrest requires a full complement of the mismatch repair protein hMLH1 , 2003, The EMBO journal.
[44] Jeffrey H. Miller,et al. In vitro and in vivo studies of MutS, MutL and MutH mutants: correlation of mismatch repair and DNA recombination. , 2003, DNA repair.
[45] P. Peltomäki. Role of DNA mismatch repair defects in the pathogenesis of human cancer. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[46] T. Kunkel,et al. Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. , 2003, Genes & development.
[47] R. Kolodner,et al. Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[48] Patrick J. Lau,et al. Transfer of the MSH2·MSH6 Complex from Proliferating Cell Nuclear Antigen to Mispaired Bases in DNA* , 2003, The Journal of Biological Chemistry.
[49] Alberto Martin,et al. AID and mismatch repair in antibody diversification , 2002, Nature Reviews Immunology.
[50] F. Collins,et al. Meiotic arrest and aneuploidy in MLH3-deficient mice , 2002, Nature Genetics.
[51] J. Jiricny,et al. Mutations within the hMLH1 and hPMS2 Subunits of the Human MutLα Mismatch Repair Factor Affect Its ATPase Activity, but Not Its Ability to Interact with hMutSα* , 2002, The Journal of Biological Chemistry.
[52] Paul Modrich,et al. Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair* , 2002, The Journal of Biological Chemistry.
[53] Liya Gu,et al. Partial Reconstitution of Human DNA Mismatch Repair In Vitro: Characterization of the Role of Human Replication Protein A , 2002, Molecular and Cellular Biology.
[54] J. Trojan,et al. hMutSα forms an ATP-dependent complex with hMutLα and hMutLβ on DNA , 2002 .
[55] R. Fishel,et al. Mismatch Repair and the Hereditary Non-polyposis Colorectal Cancer Syndrome (HNPCC) , 2002, Cancer investigation.
[56] A. Grossman,et al. Visualization of mismatch repair in bacterial cells. , 2001, Molecular cell.
[57] P. Karran. Mechanisms of tolerance to DNA damaging therapeutic drugs. , 2001, Carcinogenesis.
[58] Paul Modrich,et al. DNA Chain Length Dependence of Formation and Dynamics of hMutSα·hMutLα·Heteroduplex Complexes* , 2001, The Journal of Biological Chemistry.
[59] P. Hsieh,et al. Molecular mechanisms of DNA mismatch repair. , 2001, Mutation research.
[60] H. Kleczkowska,et al. hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci. , 2001, Genes & development.
[61] T. Sixma. DNA mismatch repair: MutS structures bound to mismatches. , 2001, Current opinion in structural biology.
[62] J. Jiricny,et al. Mismatch Recognition and DNA-dependent Stimulation of the ATPase Activity of hMutSα Is Abolished by a Single Mutation in the hMSH6 Subunit* , 2000, The Journal of Biological Chemistry.
[63] J. Jiricny. Mismatch repair: The praying hands of fidelity , 2000, Current Biology.
[64] Wei Yang,et al. Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA , 2000, Nature.
[65] Anastassis Perrakis,et al. The crystal structure of DNA mismatch repair protein MutS binding to a G·T mismatch , 2000, Nature.
[66] B. Harfe,et al. Mismatch repair proteins and mitotic genome stability. , 2000, Mutation research.
[67] C. Leonetti,et al. Sensitivity to DNA cross‐linking chemotherapeutic agents in mismatch repair‐defective cells in vitro and in xenografts , 2000, International journal of cancer.
[68] R. Kucherlapati,et al. The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. , 2000, Cancer research.
[69] J. Jiricny,et al. Mutation in the Magnesium Binding Site of hMSH6 Disables the hMutSα Sliding Clamp from Translocating along DNA* , 2000, The Journal of Biological Chemistry.
[70] R. Liskay,et al. Mammalian DNA mismatch repair. , 1999, Annual review of genetics.
[71] A. Messer,et al. Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice , 1999, Nature Genetics.
[72] Josef Jiricny,et al. Identification of hMutLβ, a Heterodimer of hMLH1 and hPMS1* , 1999, The Journal of Biological Chemistry.
[73] M. Radman,et al. HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions , 1999, Nature Genetics.
[74] R. Fishel. Signaling mismatch repair in cancer , 1999, Nature Medicine.
[75] D. Gordenin,et al. Genetic factors affecting the impact of DNA polymerase delta proofreading activity on mutation avoidance in yeast. , 1999, Genetics.
[76] Dmitry A. Gordenin,et al. The 3′→5′ Exonucleases of DNA Polymerases δ and ɛ and the 5′→3′ Exonuclease Exo1 Have Major Roles in Postreplication Mutation Avoidance in Saccharomyces cerevisiae , 1999, Molecular and Cellular Biology.
[77] C. Croce,et al. hMSH5: a human MutS homologue that forms a novel heterodimer with hMSH4 and is expressed during spermatogenesis. , 1999, Cancer research.
[78] G. Marsischky,et al. Eukaryotic DNA mismatch repair. , 1999, Current opinion in genetics & development.
[79] J. Griffith,et al. hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA. , 1999, Molecular cell.
[80] K. Bjornson,et al. Nucleotide-promoted Release of hMutSα from Heteroduplex DNA Is Consistent with an ATP-dependent Translocation Mechanism* , 1998, The Journal of Biological Chemistry.
[81] K. Bjornson,et al. DNA-dependent Activation of the hMutSα ATPase* , 1998, The Journal of Biological Chemistry.
[82] R. Kolodner,et al. The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[83] J. Jiricny,et al. hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSα , 1998, The EMBO journal.
[84] Darryl Shibata,et al. Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DMA mismatch repair , 1998, Nature Genetics.
[85] M. Wabl,et al. Mismatch repair co-opted by hypermutation. , 1998, Science.
[86] Y. L. Lin,et al. The Evolutionarily Conserved Zinc Finger Motif in the Largest Subunit of Human Replication Protein A Is Required for DNA Replication and Mismatch Repair but Not for Nucleotide Excision Repair* , 1998, The Journal of Biological Chemistry.
[87] R. Fishel,et al. The Human Mismatch Recognition Complex hMSH2-hMSH6 Functions as a Novel Molecular Switch , 1997, Cell.
[88] P. Hsieh,et al. Photocross-linking of the NH2-terminal Region of Taq MutS Protein to the Major Groove of a Heteroduplex DNA* , 1997, The Journal of Biological Chemistry.
[89] T. Waters,et al. Cytotoxic mechanism of 6-thioguanine: hMutSalpha, the human mismatch binding heterodimer, binds to DNA containing S6-methylthioguanine. , 1997, Biochemistry.
[90] P. Karran,et al. Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins. , 1997, Nucleic acids research.
[91] G. Marsischky,et al. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[92] S. Aebi,et al. The role of DNA mismatch repair in platinum drug resistance. , 1996, Cancer research.
[93] Asad Umar,et al. Requirement for PCNA in DNA Mismatch Repair at a Step Preceding DNA Resynthesis , 1996, Cell.
[94] J. Jiricny,et al. hMutSβ, a heterodimer of hMSH2 and hMSH3, binds to insertion/deletion loops in DNA , 1996, Current Biology.
[95] Qinguo Zheng,et al. Role of Postreplicative DNA Mismatch Repair in the Cytotoxic Action of Thioguanine , 1996, Science.
[96] C. Boland,et al. Loss of DNA mismatch repair in acquired resistance to cisplatin. , 1996, Cancer research.
[97] R. Sinden,et al. Mismatch repair in Escherichia coli enhances instability of (CTG)n triplet repeats from human hereditary diseases. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[98] Jian Yu,et al. Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis , 1995, Cell.
[99] M. Radman,et al. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer , 1995, Cell.
[100] P. Modrich,et al. Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to tumor cells. , 1995, Science.
[101] J. Jiricny,et al. GTBP, a 160-kilodalton protein essential for mismatch-binding activity in human cells. , 1995, Science.
[102] P. Modrich,et al. Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[103] T. Kunkel. Slippery DNA and diseases , 1993, Nature.
[104] W. Fang,et al. Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of the bacterial reaction. , 1993, The Journal of biological chemistry.
[105] T. Kunkel,et al. Heteroduplex repair in extracts of human HeLa cells. , 1991, The Journal of biological chemistry.
[106] P. Modrich,et al. Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[107] E. Koonin,et al. Superfamily of UvrA-related NTP-binding proteins. Implications for rational classification of recombination/repair systems. , 1990, Journal of molecular biology.
[108] M. Radman,et al. The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants , 1989, Nature.
[109] P. Modrich,et al. DNA mismatch correction in a defined system. , 1989, Science.
[110] J. Jiricny,et al. d(GATC) sequences influence Escherichia coli mismatch repair in a distance-dependent manner from positions both upstream and downstream of the mismatch. , 1988, Nucleic acids research.
[111] H. Fritz,et al. Different base/base mismatches are corrected with different efficiencies by the methyl-directed DNA mismatch-repair system of E. coli , 1984, Cell.
[112] J. Dunn,et al. Identification of base mismatches recognized by the heteroduplex-DNA-repair system of Streptococcus pneumoniae , 1982, Cell.
[113] J. Walker,et al. Distantly related sequences in the alpha‐ and beta‐subunits of ATP synthase, myosin, kinases and other ATP‐requiring enzymes and a common nucleotide binding fold. , 1982, The EMBO journal.
[114] D. Lilley,et al. Human MutScv recognizes damaged DNA base pairs containing 06-methylguanine, 04-methylthymine, or the cisplatin-d(GpG) adduct , 2005 .
[115] A. Lajtha,et al. Genome instability in cancer development , 2005 .
[116] J. Jiricny,et al. DNA mismatch repair and colon cancer. , 2005, Advances in experimental medicine and biology.
[117] C. Woo,et al. The generation of antibody diversity through somatic hypermutation and class switch recombination. , 2004, Genes & development.
[118] P. Hsieh,et al. Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair. , 2001, Molecular cell.
[119] M. Inouye,et al. GHKL, an emergent ATPase/kinase superfamily. , 2000, Trends in biochemical sciences.
[120] B. Harfe,et al. DNA mismatch repair and genetic instability. , 2000, Annual review of genetics.