Identification of GDF15 peptide fragments inhibiting GFRAL receptor signaling
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[1] K. Yea,et al. GDNF family receptor alpha‐like antagonist antibody alleviates chemotherapy‐induced cachexia in melanoma‐bearing mice , 2023, Journal of cachexia, sarcopenia and muscle.
[2] P. Emmerson,et al. Discovery, development, and clinical proof of mechanism of LY3463251, a long-acting GDF15 receptor agonist. , 2023, Cell metabolism.
[3] J. Routy,et al. Coping With Stress: The Mitokine GDF-15 as a Biomarker of COVID-19 Severity , 2022, Frontiers in Immunology.
[4] Ki Baek Lee,et al. Body weight regulation via MT1-MMP-mediated cleavage of GFRAL , 2022, Nature Metabolism.
[5] J. Routy,et al. GDF15/GFRAL Pathway as a Metabolic Signature for Cachexia in Patients with Cancer , 2021, Journal of Cancer.
[6] M. Birnbaum,et al. GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates. , 2020, Cell metabolism.
[7] Subhash D. Katewa,et al. Antibody-mediated inhibition of GDF15–GFRAL activity reverses cancer cachexia in mice , 2020, Nature Medicine.
[8] Subhash D. Katewa,et al. Antibody-mediated inhibition of GDF15–GFRAL activity reverses cancer cachexia in mice , 2020, Nature Medicine.
[9] X. Bai,et al. Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands , 2019, eLife.
[10] M. Pisani,et al. GDF15 Is an Inflammation-Induced Central Mediator of Tissue Tolerance , 2019, Cell.
[11] M. Korc,et al. Cancer-associated cachexia , 2018, Nature Reviews Disease Primers.
[12] J. Wojtaszewski,et al. Exercise increases circulating GDF15 in humans , 2018, Molecular metabolism.
[13] Hantao Liu,et al. Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys , 2017, Science Translational Medicine.
[14] Jie Tang,et al. Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15 , 2017, Nature.
[15] Søren B. Padkjær,et al. GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand , 2017, Nature Medicine.
[16] T. Cash-Mason,et al. GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates , 2017, Nature Medicine.
[17] P. Emmerson,et al. The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL , 2017, Nature Medicine.
[18] Hyun Jin Kim,et al. Growth Differentiation Factor 15 Predicts Chronic Liver Disease Severity , 2016, Gut and liver.
[19] A. Vigano,et al. MAP3K11/GDF15 axis is a critical driver of cancer cachexia , 2015, Journal of cachexia, sarcopenia and muscle.
[20] Richard Nicoletti,et al. Plasma growth differentiation factor 15 is associated with weight loss and mortality in cancer patients , 2015, Journal of cachexia, sarcopenia and muscle.
[21] F. López‐Soriano,et al. Cancer cachexia: understanding the molecular basis , 2014, Nature Reviews Cancer.
[22] D. Glass,et al. Cancer cachexia: mediators, signaling, and metabolic pathways. , 2012, Cell metabolism.
[23] Tiago Rito,et al. Studying Protein—Protein Interactions Using Peptide Arrays , 2011 .
[24] Paula Ravasco,et al. Definition and classification of cancer cachexia: an international consensus. , 2011, The Lancet. Oncology.
[25] S. Rüdiger,et al. Studying protein-protein interactions using peptide arrays. , 2011, Chemical Society reviews.
[26] M. Matoulek,et al. Increased serum concentrations of macrophage inhibitory cytokine-1 in patients with obesity and type 2 diabetes mellitus: the influence of very low calorie diet. , 2009, European journal of endocrinology.
[27] P. Ponikowski,et al. Cachexia: a new definition. , 2008, Clinical nutrition.
[28] W. D. Fairlie,et al. Tumor-induced anorexia and weight loss are mediated by the TGF-β superfamily cytokine MIC-1 , 2007, Nature Medicine.
[29] P. Ponikowski,et al. Prognostic utility of growth differentiation factor-15 in patients with chronic heart failure. , 2007, Journal of the American College of Cardiology.
[30] J. Welsh,et al. Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[31] W. D. Fairlie,et al. The transforming growth factor-ss superfamily cytokine macrophage inhibitory cytokine-1 is present in high concentrations in the serum of pregnant women. , 2000, The Journal of clinical endocrinology and metabolism.
[32] W. D. Fairlie,et al. MIC‐1 is a novel TGF‐β superfamily cytokine associated with macrophage activation , 1999, Journal of leukocyte biology.
[33] M. Soares,et al. Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta. , 1997, Gene.
[34] W. D. Fairlie,et al. MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[35] R. Hromas,et al. PLAB, a novel placental bone morphogenetic protein. , 1997, Biochimica et biophysica acta.
[36] The International Consensus , 1992, The Rights of the Child and the Changing Image of Childhood.
[37] D. Morgan. A new definition. , 1983, Journal of the American Dental Association.
[38] W. Dewys. Pathophysiology of cancer cachexia: current understanding and areas for future research. , 1982, Cancer research.
[39] 上田晃久,et al. Macrophage inhibitory cytokine‐1(MIC‐1)と糖尿病性腎症の関連について , 2016 .
[40] J. Carrero,et al. Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease. , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[41] M. Kunesova,et al. The influence of very-low-calorie-diet on serum leptin, soluble leptin receptor, adiponectin and resistin levels in obese women. , 2006, Physiological research.