Protein kinase C-α (PKCα) modulates cell apoptosis by stimulating nuclear translocation of NF-kappa-B p65 in urothelial cell carcinoma of the bladder

[1]  Youli Cai,et al.  Theaflavin alleviates inflammatory response and brain injury induced by cerebral hemorrhage via inhibiting the nuclear transcription factor kappa β-related pathway in rats , 2018, Drug design, development and therapy.

[2]  Xi Chen,et al.  PKCδ reveals a tumor promoter function by promoting cell proliferation and migration in somatotropinomas. , 2018, International journal of clinical and experimental pathology.

[3]  Wanqing Chen,et al.  Urologic cancer in China. , 2016, Japanese journal of clinical oncology.

[4]  A. Jemal,et al.  Cancer statistics in China, 2015 , 2016, CA: a cancer journal for clinicians.

[5]  A. Jemal,et al.  Cancer statistics, 2016 , 2016, CA: a cancer journal for clinicians.

[6]  Zhe Zhang,et al.  Reduction of protein kinase C α (PKC-α) promote apoptosis via down-regulation of Dicer in bladder cancer , 2015, Journal of cellular and molecular medicine.

[7]  R. Ghosh,et al.  To be an ally or an adversary in bladder cancer: the NF-κB story has not unfolded. , 2015, Carcinogenesis.

[8]  L. Klotz,et al.  World Urologic Oncology Federation Bladder Cancer Prevention Program: a global initiative. , 2015, Urologic oncology.

[9]  Inder M. Verma,et al.  NF-κB, an Active Player in Human Cancers , 2014, Cancer Immunology Research.

[10]  C. Luo,et al.  A new PKCα/β/TBX3/E-cadherin pathway is involved in PLCε-regulated invasion and migration in human bladder cancer cells. , 2014, Cellular signalling.

[11]  Zhe Zhang,et al.  PKC α regulates netrin-1/UNC5B-mediated survival pathway in bladder cancer , 2014, BMC Cancer.

[12]  G. Ghosh,et al.  NF‐κB regulation: lessons from structures , 2012, Immunological reviews.

[13]  Xin Lin,et al.  CARMA1‐mediated NF‐κB and JNK activation in lymphocytes , 2009, Immunological reviews.

[14]  Michael Karin,et al.  NF-kappaB and cancer-identifying targets and mechanisms. , 2008, Current opinion in genetics & development.

[15]  M. Kazanietz,et al.  Protein kinase C and other diacylglycerol effectors in cancer , 2007, Nature Reviews Cancer.

[16]  S. Cho,et al.  PMA-induced up-regulation of MMP-9 is regulated by a PKCα-NF-κB cascade in human lung epithelial cells , 2007, Experimental & Molecular Medicine.

[17]  S. Cho,et al.  PMA-induced up-regulation of MMP-9 is regulated by a PKCalpha-NF-kappaB cascade in human lung epithelial cells. , 2007, Experimental & molecular medicine.

[18]  R. Sylvester.  Natural History, Recurrence, and Progression in Superficial Bladder Cancer , 2006, TheScientificWorldJournal.

[19]  Ze-liang Li,et al.  Role of protein kinase C-alpha in superficial bladder carcinoma recurrence. , 2005, Urology.

[20]  T. Németh,et al.  Tumor grade-dependent alterations in the protein kinase C isoform pattern in urinary bladder carcinomas. , 2004, European urology.

[21]  J. Koivunen,et al.  Protein Kinase C α/β Inhibitor Go6976 Promotes Formation of Cell Junctions and Inhibits Invasion of Urinary Bladder Carcinoma Cells , 2004, Cancer Research.

[22]  J. Koivunen,et al.  Protein kinase C alpha/beta inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells. , 2004, Cancer research.

[23]  D. Sliva,et al.  Protein Kinase C Induces Motility of Breast Cancers by Upregulating Secretion of Urokinase-Type Plasminogen Activator through Activation of AP-1 and NF-κB , 2002 .

[24]  D. Sliva,et al.  Protein kinase C induces motility of breast cancers by upregulating secretion of urokinase-type plasminogen activator through activation of AP-1 and NF-kappaB. , 2002, Biochemical and biophysical research communications.

[25]  H. Pahl,et al.  Activators and target genes of Rel/NF-kappaB transcription factors. , 1999, Oncogene.

[26]  A. Aderem,et al.  PMA‐induced reduction in invasiveness is associated with hyperphosphorylation of MARCKS and talin in invasive bladder cancer cells , 1998, International journal of cancer.

[27]  A. Israël,et al.  IκB proteins: structure, function and regulation , 1997 .

[28]  A. Israël,et al.  I kappa B proteins: structure, function and regulation. , 1997, Seminars in cancer biology.

[29]  V. Castronovo,et al.  The NF-kappa B transcription factor and cancer: high expression of NF-kappa B- and I kappa B-related proteins in tumor cell lines. , 1994, Biochemical pharmacology.

[30]  G. Martiny-Baron,et al.  Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976. , 1993, The Journal of biological chemistry.

[31]  A. Basu,et al.  The potential of protein kinase C as a target for anticancer treatment. , 1993, Pharmacology & therapeutics.

[32]  N. Dubrawsky.  Cancer statistics , 1989, CA: a cancer journal for clinicians.

[33]  Y. Nishizuka,et al.  The molecular heterogeneity of protein kinase C and its implications for cellular regulation , 1988, Nature.