Effects of X-chromosome Tenomodulin Genetic Variants on Obesity in a Children’s Cohort and Implications of the Gene in Adipocyte Metabolism
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L. Moreno | R. Leis | Á. Gil | J. Olza | C. Gómez-Llorente | M. Gil-Campos | C. Aguilera | G. Bueno | Rocío Vázquez-Cobela | R. Cañete | A. Anguita-Ruiz | A. Rupérez | F. Ruiz-Ojeda
[1] M. Akash,et al. Tumor Necrosis Factor‐Alpha: Role in Development of Insulin Resistance and Pathogenesis of Type 2 Diabetes Mellitus , 2018, Journal of cellular biochemistry.
[2] Accounting for sex in the genome , 2017, Nature Medicine.
[3] D. Docheva,et al. Tenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing , 2017, Cell Death & Disease.
[4] Yilin Cao,et al. Enhanced tenogenic differentiation and tendon‐like tissue formation by tenomodulin overexpression in murine mesenchymal stem cells , 2017, Journal of tissue engineering and regenerative medicine.
[5] Joshua A. Salomon,et al. Health Effects of Overweight and Obesity in 195 Countries over 25 Years. , 2017, The New England journal of medicine.
[6] J. Breda,et al. Overweight and Obesity in Children under 5 Years: Surveillance Opportunities and Challenges for the WHO European Region , 2017, Front. Public Health.
[7] G. Hotamışlıgil. Inflammation, metaflammation and immunometabolic disorders , 2017, Nature.
[8] Prasenjit Manna,et al. Vitamin D supplementation inhibits oxidative stress and upregulate SIRT1/AMPK/GLUT4 cascade in high glucose-treated 3T3L1 adipocytes and in adipose tissue of high fat diet-fed diabetic mice. , 2017, Archives of biochemistry and biophysics.
[9] W. Liu,et al. Conditional tenomodulin overexpression favors tenogenic lineage differentiation of transgenic mouse derived cells. , 2017, Gene.
[10] Beryl B. Cummings,et al. Landscape of X chromosome inactivation across human tissues , 2016, Nature.
[11] D. Docheva,et al. Tenogenic modulating insider factor: Systematic assessment on the functions of tenomodulin gene. , 2016, Gene.
[12] D. Langin,et al. Adipocyte lipolysis and insulin resistance. , 2016, Biochimie.
[13] S. Naimov,et al. A Prospectus of Tenomodulin , 2016, Folia medica.
[14] Marina T. DiStefano,et al. Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion , 2016, Nature Communications.
[15] S. Bornstein,et al. Anti-inflammatory properties of bone morphogenetic protein 4 in human adipocytes , 2016, International Journal of Obesity.
[16] A. Clark,et al. Strong Constraint on Human Genes Escaping X-Inactivation Is Modulated by their Expression Level and Breadth in Both Sexes , 2015, Molecular biology and evolution.
[17] A. Keinan,et al. XWAS: A Software Toolset for Genetic Data Analysis and Association Studies of the X Chromosome. , 2015, The Journal of heredity.
[18] S. E. Park,et al. Adiponectin deletion impairs insulin signaling in insulin-sensitive but not insulin-resistant 3T3-L1 adipocytes. , 2015, Life sciences.
[19] S. Yokoyama,et al. Crystal structures of the human adiponectin receptors , 2015, Nature.
[20] Á. Gil,et al. Genome-Wide Expression in Visceral Adipose Tissue from Obese Prepubertal Children , 2015, International journal of molecular sciences.
[21] S. Hirabara,et al. Palmitoleic acid (n-7) increases white adipocytes GLUT4 content and glucose uptake in association with AMPK activation , 2014, Lipids in Health and Disease.
[22] R. Govers. Molecular mechanisms of GLUT4 regulation in adipocytes. , 2014, Diabetes & metabolism.
[23] Aaron J. Sams,et al. Accounting for eXentricities: Analysis of the X Chromosome in GWAS Reveals X-Linked Genes Implicated in Autoimmune Diseases , 2014, bioRxiv.
[24] Carolyn J. Brown,et al. Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation , 2014, Human molecular genetics.
[25] A. Keinan,et al. XWAS: A Software Toolset for Genetic Data Analysis and Association Studies of the X Chromosome , 2014, bioRxiv.
[26] C. Bing,et al. Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes , 2014, American journal of physiology. Endocrinology and metabolism.
[27] Andreas Ziegler,et al. How to Include Chromosome X in Your Genome‐Wide Association Study , 2014, Genetic epidemiology.
[28] M. Moreno-Aliaga,et al. Differential Proinflammatory and Oxidative Stress Response and Vulnerability to Metabolic Syndrome in Habitual High-Fat Young Male Consumers Putatively Predisposed by Their Genetic Background , 2013, International journal of molecular sciences.
[29] T. Manolio,et al. eXclusion: toward integrating the X chromosome in genome-wide association analyses. , 2013, American journal of human genetics.
[30] A. Olson. Regulation of GLUT4 and Insulin-Dependent Glucose Flux , 2012, ISRN molecular biology.
[31] Leif Groop,et al. Differential gene expression in adipose tissue from obese human subjects during weight loss and weight maintenance. , 2012, The American journal of clinical nutrition.
[32] Peter Tontonoz,et al. The Number of X Chromosomes Causes Sex Differences in Adiposity in Mice , 2012, PLoS genetics.
[33] A. Vidal-Puig,et al. Ablation of Pparg2 impairs lipolysis and reveals murine strain differences in lipolytic responses , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[34] R. Leis,et al. A gene variant of 11β-hydroxysteroid dehydrogenase type 1 is associated with obesity in children , 2012, International Journal of Obesity.
[35] Melanie Bahlo,et al. X chromosome association testing in genome wide association studies , 2011, Genetic epidemiology.
[36] Carey N Lumeng,et al. Inflammatory links between obesity and metabolic disease. , 2011, The Journal of clinical investigation.
[37] Ruijie Liu,et al. Comparing genotyping algorithms for Illumina's Infinium whole-genome SNP BeadChips , 2011, BMC Bioinformatics.
[38] B. McCrindle. Assessment and management of hypertension in children and adolescents , 2010, Nature Reviews Cardiology.
[39] C. Glass,et al. Macrophages, inflammation, and insulin resistance. , 2010, Annual review of physiology.
[40] M. Uusitupa,et al. Tenomodulin gene and obesity-related phenotypes , 2010, Annals of medicine.
[41] K. Hetrick,et al. Application of sex-specific single-nucleotide polymorphism filters in genome-wide association data , 2009, BMC proceedings.
[42] Judy H. Cho,et al. Finding the missing heritability of complex diseases , 2009, Nature.
[43] P. Froguel,et al. Tenomodulin is highly expressed in adipose tissue, increased in obesity, and down-regulated during diet-induced weight loss. , 2009, The Journal of clinical endocrinology and metabolism.
[44] B. Maher. Personal genomes: The case of the missing heritability , 2008, Nature.
[45] J. Tuomilehto,et al. The genetic variation in the tenomodulin gene is associated with serum total and LDL cholesterol in a body size-dependent manner , 2008, International Journal of Obesity.
[46] Y. Okada,et al. Local Tenomodulin Absence, Angiogenesis, and Matrix Metalloproteinase Activation Are Associated With the Rupture of the Chordae Tendineae Cordis , 2008, Circulation.
[47] M. Uusitupa,et al. Single nucleotide polymorphisms of the tenomodulin gene (TNMD) in age-related macular degeneration , 2008, Molecular vision.
[48] J. Tuomilehto,et al. The genetic variation of the tenomodulin gene (TNMD) is associated with serum levels of systemic immune mediators—the Finnish Diabetes Prevention Study , 2008, Genetics in Medicine.
[49] M. Czech,et al. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes , 2008, Nature Reviews Molecular Cell Biology.
[50] D. Clayton,et al. Testing for association on the X chromosome , 2008, Biostatistics.
[51] L. Niskanen,et al. Weight reduction modulates expression of genes involved in extracellular matrix and cell death: the GENOBIN study , 2008, International Journal of Obesity.
[52] M. Lorenzo,et al. Insulin resistance associated to obesity: the link TNF-alpha , 2008, Archives of physiology and biochemistry.
[53] Manuel A. R. Ferreira,et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.
[54] J. Tuomilehto,et al. Tenomodulin is Associated with Obesity and Diabetes Risk: The Finnish Diabetes Prevention Study , 2007, Obesity.
[55] T. Kanaya,et al. Identification of peroxisome-proliferator responsive element in the mouse HSL gene. , 2007, Biochemical and biophysical research communications.
[56] A. Goldfine,et al. Inflammation and insulin resistance. , 2006, The Journal of clinical investigation.
[57] W. Wahli,et al. The Fasting-induced Adipose Factor/Angiopoietin-like Protein 4 Is Physically Associated with Lipoproteins and Governs Plasma Lipid Levels and Adiposity* , 2006, Journal of Biological Chemistry.
[58] S. Gabriel,et al. Efficiency and power in genetic association studies , 2005, Nature Genetics.
[59] H. Willard,et al. X-inactivation profile reveals extensive variability in X-linked gene expression in females , 2005, Nature.
[60] Mark Daly,et al. Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..
[61] Denitsa Docheva,et al. Tenomodulin Is Necessary for Tenocyte Proliferation and Tendon Maturation , 2005, Molecular and Cellular Biology.
[62] G. Hotamisligil,et al. Inflammatory pathways and insulin action , 2003, International Journal of Obesity.
[63] S. Horvath,et al. Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation. , 2003, Brain research. Molecular brain research.
[64] J. Miyazaki,et al. Expression and localization of tenomodulin, a transmembrane type chondromodulin-I-related angiogenesis inhibitor, in mouse eyes. , 2003, Investigative ophthalmology & visual science.
[65] S. Dudoit,et al. Multiple Hypothesis Testing in Microarray Experiments , 2003 .
[66] S. Uchida,et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase , 2002, Nature Medicine.
[67] Laura L. Carruth,et al. Sex chromosome genes directly affect brain sexual differentiation , 2002, Nature Neuroscience.
[68] M. Matsuda,et al. Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 , 2002, Nature Medicine.
[69] Y. Benjamini,et al. THE CONTROL OF THE FALSE DISCOVERY RATE IN MULTIPLE TESTING UNDER DEPENDENCY , 2001 .
[70] A. Meindl,et al. A novel gene, tendin, is strongly expressed in tendons and ligaments and shows high homology with chondromodulin‐I , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.
[71] M. Pfaffl,et al. A new mathematical model for relative quantification in real-time RT-PCR. , 2001, Nucleic acids research.
[72] Y. Oshima,et al. Molecular cloning of tenomodulin, a novel chondromodulin-I related gene. , 2001, Biochemical and biophysical research communications.
[73] T. Valle,et al. The Finnish Diabetes Prevention Study , 2000, British Journal of Nutrition.
[74] P. Robbins,et al. Viral Vectors for Gene Therapy , 2019, Methods in Molecular Biology.
[75] H. Inoue,et al. Identification of Chondromodulin I as a Novel Endothelial Cell Growth Inhibitor , 1997, The Journal of Biological Chemistry.
[76] C. Bishop,et al. The genetic basis of XX-XY differences present before gonadal sex differentiation in the mouse. , 1995, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[77] I. Reisert,et al. Sexual differentiation of monoaminergic neurons - genetic or epigenetic? , 1991, Trends in Neurosciences.
[78] G. Hommel. A stagewise rejective multiple test procedure based on a modified Bonferroni test , 1988 .
[79] R. Bhadra,et al. NIH Public Access , 2014 .
[80] R Core Team,et al. R: A language and environment for statistical computing. , 2014 .
[81] M. Al‐Rubeai,et al. Viral Vectors for Gene Therapy , 2011, Methods in Molecular Biology.
[82] M. Lorenzo,et al. Insulin resistance associated to obesity: the link TNF-alpha. , 2008, Archives of physiology and biochemistry.
[83] B. Maher,et al. The case of the missing heritability , 2008 .
[84] Y. Ahn,et al. Regulation of glucose transporter type 4 isoform gene expression in muscle and adipocytes , 2007, IUBMB life.
[85] 임승순,et al. Regulation of glucose transporter type 4 isoform gene expression in muscle and adipocytes , 2007 .
[86] Luigi Naldini,et al. Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics , 2001, Nature Medicine.
[87] Y. Benjamini,et al. Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .