FXR is a molecular target for the effects of vertical sleeve gastrectomy
暂无分享,去创建一个
V. Tremaroli | F. Bäckhed | R. Seeley | Rohit Kohli | R. Karns | D. Sandoval | P. Kovatcheva-Datchary | C. Clemmensen | Andriy Myronovych | H. Wilson-Pérez | K. Ryan | Rebekah A. Karns
[1] J. Clemente,et al. Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice , 2013, Science.
[2] M. Bessler,et al. Very Low–Calorie Diet Mimics the Early Beneficial Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity and β-Cell Function in Type 2 Diabetic Patients , 2013, Diabetes.
[3] M. Blaut,et al. Differences in Mucosal Gene Expression in the Colon of Two Inbred Mouse Strains after Colonization with Commensal Gut Bacteria , 2013, PloS one.
[4] B. Aronow,et al. Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner , 2013, Obesity.
[5] R. Seeley,et al. Vertical Sleeve Gastrectomy Is Effective in Two Genetic Mouse Models of Glucagon-Like Peptide 1 Receptor Deficiency , 2013, Diabetes.
[6] W. Strodel,et al. A Role for Fibroblast Growth Factor 19 and Bile Acids in Diabetes Remission After Roux-en-Y Gastric Bypass , 2013, Diabetes Care.
[7] Fredrik H. Karlsson,et al. Gut metagenome in European women with normal, impaired and diabetic glucose control , 2013, Nature.
[8] Lee M. Kaplan,et al. Conserved Shifts in the Gut Microbiota Due to Gastric Bypass Reduce Host Weight and Adiposity , 2013, Science Translational Medicine.
[9] S. Klein,et al. Weight loss induced by Roux-en-Y gastric bypass but not laparoscopic adjustable gastric banding increases circulating bile acids. , 2013, The Journal of clinical endocrinology and metabolism.
[10] F. Bäckhed,et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. , 2013, Cell metabolism.
[11] Yongjie Ma,et al. Synthetic FXR Agonist GW4064 Prevents Diet-Induced Hepatic Steatosis and Insulin Resistance , 2013, Pharmaceutical Research.
[12] Eleazar Eskin,et al. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. , 2013, Cell metabolism.
[13] S. Klein,et al. Gastric bypass and banding equally improve insulin sensitivity and β cell function. , 2012, The Journal of clinical investigation.
[14] W. D. de Vos,et al. Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women , 2012, Gut.
[15] M. Wong,et al. Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters , 2012, The Pharmacogenomics Journal.
[16] E. Zoetendal,et al. Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. , 2012, Gastroenterology.
[17] Qiang Feng,et al. A metagenome-wide association study of gut microbiota in type 2 diabetes , 2012, Nature.
[18] Barbara Gross,et al. Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease , 2012, Journal of Lipid Research.
[19] F. Haj,et al. Vertical sleeve gastrectomy improves glucose and lipid metabolism and delays diabetes onset in UCD-T2DM rats. , 2012, Endocrinology.
[20] R. Seeley,et al. All bariatric surgeries are not created equal: insights from mechanistic comparisons. , 2012, Endocrine reviews.
[21] S. Woods,et al. Central nervous system mechanisms linking the consumption of palatable high-fat diets to the defense of greater adiposity. , 2012, Cell metabolism.
[22] V. Tremaroli,et al. Analysis of gut microbial regulation of host gene expression along the length of the gut and regulation of gut microbial ecology through MyD88 , 2011, Gut.
[23] Tetsuya Hayashi,et al. Bile acid is a host factor that regulates the composition of the cecal microbiota in rats. , 2011, Gastroenterology.
[24] S. Woods,et al. Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats. , 2011, Gastroenterology.
[25] M. Orešič,et al. Farnesoid X Receptor Deficiency Improves Glucose Homeostasis in Mouse Models of Obesity , 2011, Diabetes.
[26] J. Auwerx,et al. Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor (FXR) Agonist Induces Obesity and Diabetes through Reduced Energy Expenditure* , 2011, The Journal of Biological Chemistry.
[27] J. Tap,et al. Differential Adaptation of Human Gut Microbiota to Bariatric Surgery–Induced Weight Loss , 2010, Diabetes.
[28] E. Want,et al. Systemic gut microbial modulation of bile acid metabolism in host tissue compartments , 2010, Proceedings of the National Academy of Sciences.
[29] Janne Nikkilä,et al. Comparative analysis of fecal DNA extraction methods with phylogenetic microarray: effective recovery of bacterial and archaeal DNA using mechanical cell lysis. , 2010, Journal of microbiological methods.
[30] William A. Walters,et al. QIIME allows analysis of high-throughput community sequencing data , 2010, Nature Methods.
[31] R. Ley,et al. Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5 , 2010, Science.
[32] J. Donaldson,et al. Effect of bile salts on the DNA and membrane integrity of enteric bacteria. , 2009, Journal of medical microbiology.
[33] Rob Knight,et al. PyNAST: a flexible tool for aligning sequences to a template alignment , 2009, Bioinform..
[34] J. Holst,et al. Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution to Improved Glucose and Lipid Metabolism , 2009, Obesity.
[35] Adam P. Arkin,et al. FastTree: Computing Large Minimum Evolution Trees with Profiles instead of a Distance Matrix , 2009, Molecular biology and evolution.
[36] M. Crowell,et al. Human gut microbiota in obesity and after gastric bypass , 2009, Proceedings of the National Academy of Sciences.
[37] W. Pories. Bariatric surgery: risks and rewards. , 2008, The Journal of clinical endocrinology and metabolism.
[38] R. Ley,et al. Innate immunity and intestinal microbiota in the development of Type 1 diabetes , 2008, Nature.
[39] Johan Auwerx,et al. Targeting bile-acid signalling for metabolic diseases , 2008, Nature Reviews Drug Discovery.
[40] L. Fulton,et al. Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. , 2008, Cell host & microbe.
[41] R. Knight,et al. Error-correcting barcoded primers for pyrosequencing hundreds of samples in multiplex , 2008, Nature Methods.
[42] T. Alexandrides,et al. Weight Loss, Appetite Suppression, and Changes in Fasting and Postprandial Ghrelin and Peptide-YY Levels After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy: A Prospective, Double Blind Study , 2008, Annals of surgery.
[43] E. Mardis,et al. An obesity-associated gut microbiome with increased capacity for energy harvest , 2006, Nature.
[44] Folkert Kuipers,et al. The Farnesoid X Receptor Modulates Adiposity and Peripheral Insulin Sensitivity in Mice* , 2006, Journal of Biological Chemistry.
[45] Ke Ma,et al. Farnesoid X receptor is essential for normal glucose homeostasis. , 2006, The Journal of clinical investigation.
[46] T. Willson,et al. Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[47] R. Knight,et al. UniFrac: a New Phylogenetic Method for Comparing Microbial Communities , 2005, Applied and Environmental Microbiology.
[48] F. Bäckhed,et al. Obesity alters gut microbial ecology. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[49] J. Magdalou,et al. The human colonic microflora influences the alterations of xenobiotic-metabolizing enzymes by catechins in male F344 rats. , 2003, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[50] Masahiro Tohkin,et al. Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis , 2000, Cell.
[51] R. Evans,et al. Improved insulin-sensitivity in mice heterozygous for PPAR-γ deficiency , 2000 .
[52] G T Watts,et al. Risks and rewards. , 1977, British medical journal.
[53] R. Seeley,et al. The effects of vertical sleeve gastrectomy in rodents are ghrelin independent. , 2013, Gastroenterology.
[54] W. Verstraete,et al. Dietary modulation of clostridial cluster XIVa gut bacteria (Roseburia spp.) by chitin-glucan fiber improves host metabolic alterations induced by high-fat diet in mice. , 2012, The Journal of nutritional biochemistry.
[55] R. Abramof. Bariatric Surgery versus Intensive Medical Therapy in Obese Patients with Diabetes , 2012 .
[56] R. Evans,et al. Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency. , 2000, The Journal of clinical investigation.