Trilostane therapy for hyperadrenocorticism in three dogs with adrenocortical metastasis

IN dogs, more than half of the adrenal tumours responsible for hyperadrenocorticism are malignant ([Reusch and Feldman 1991][1]). They can be metastasised by the time of diagnosis or after surgical resection. Medical management is therefore required to control the clinical signs. Trilostane is an

[1]  P. Devauchelle,et al.  Plasma pro-opiomelanocortin, pro-adrenocorticotropin hormone, and pituitary adenoma size in dogs with Cushing's disease. , 2005, Journal of veterinary internal medicine.

[2]  S. Reid,et al.  A comparison of the survival times of dogs treated with mitotane or trilostane for pituitary-dependent hyperadrenocorticism. , 2005, Journal of veterinary internal medicine.

[3]  K. Hurley,et al.  Trilostane treatment of a dog with functional adrenocortical neoplasia. , 2003, The Journal of small animal practice.

[4]  I. Ramsey,et al.  Trilostane treatment of 78 dogs with pituitary-dependent hyperadrenocorticism , 2002, Veterinary Record.

[5]  C. Reusch,et al.  Results of clinical examinations, laboratory tests, and ultrasonography in dogs with pituitary-dependent hyperadrenocorticism treated with trilostane. , 2002, American journal of veterinary research.

[6]  C. Reusch,et al.  [Mitotane treatment in a dog with a recurring adrenocortical carcinoma--a case report]. , 1999, Schweizer Archiv fur Tierheilkunde.

[7]  R. Nelson,et al.  Use of low- and high-dose dexamethasone tests for distinguishing pituitary-dependent from adrenal tumor hyperadrenocorticism in dogs. , 1996, Journal of the American Veterinary Medical Association.

[8]  M. Peterson,et al.  Mitotane treatment of 32 dogs with cortisol-secreting adrenocortical neoplasms. , 1994, Journal of the American Veterinary Medical Association.

[9]  C. Reusch,et al.  Canine hyperadrenocorticism due to adrenocortical neoplasia. Pretreatment evaluation of 41 dogs. , 1991, Journal of veterinary internal medicine.

[10]  R. Nelson,et al.  Canine and Feline Endocrinology and Reproduction , 1987 .