TAK1 is a ubiquitin-dependent kinase of MKK and IKK
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Zhijian J. Chen | J. Inoue | L. Deng | chen wang | G. Akkaraju | Mei Hong
[1] D. Goeddel,et al. Defective Lymphotoxin-β Receptor-Induced NF-κB Transcriptional Activity in NIK-Deficient Mice , 2001, Science.
[2] S. Ghosh,et al. Toll-like receptor-mediated NF-kappaB activation: a phylogenetically conserved paradigm in innate immunity. , 2001, The Journal of clinical investigation.
[3] Zhijian J. Chen,et al. Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain , 2000, Cell.
[4] R. Davis,et al. Signal Transduction by the JNK Group of MAP Kinases , 2000, Cell.
[5] H. Nakano,et al. The atypical PKC‐interacting protein p62 channels NF‐κB activation by the IL‐1–TRAF6 pathway , 2000, The EMBO journal.
[6] K. Irie,et al. TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. , 2000, Molecular cell.
[7] Sakae Tanaka,et al. Severe osteopetrosis, defective interleukin‐1 signalling and lymph node organogenesis in TRAF6‐deficient mice , 1999, Genes to cells : devoted to molecular & cellular mechanisms.
[8] M. Karin,et al. Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. , 1999, Genes & development.
[9] S. Morony,et al. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. , 1999, Genes & development.
[10] Quan Zhao,et al. Mitogen-activated Protein Kinase/ERK Kinase Kinases 2 and 3 Activate Nuclear Factor-κB through IκB Kinase-α and IκB Kinase-β* , 1999, The Journal of Biological Chemistry.
[11] J. Ninomiya-Tsuji,et al. The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway , 1999, Nature.
[12] C. Pickart,et al. Noncanonical MMS2-Encoded Ubiquitin-Conjugating Enzyme Functions in Assembly of Novel Polyubiquitin Chains for DNA Repair , 1999, Cell.
[13] Matthias Mann,et al. IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation , 1997 .
[14] D. Wallach,et al. MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1 , 1997, Nature.
[15] T. Maniatis,et al. Activation of the IκBα Kinase Complex by MEKK1, a Kinase of the JNK Pathway , 1997, Cell.
[16] E. Kieff,et al. Identification of TRAF6, a Novel Tumor Necrosis Factor Receptor-associated Factor Protein That Mediates Signaling from an Amino-terminal Domain of the CD40 Cytoplasmic Region* , 1996, The Journal of Biological Chemistry.
[17] B. Seed,et al. RIP mediates tumor necrosis factor receptor 1 activation of NF‐kappaB but not Fas/APO‐1‐initiated apoptosis. , 1996, The EMBO journal.
[18] Zhaodan Cao,et al. TRAF6 is a signal transducer for interleukin-1 , 1996, Nature.
[19] M. Farrar,et al. Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization , 1996, Nature.
[20] Xiaodong Wang,et al. Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c , 1996, Cell.
[21] T. Maniatis,et al. Site-Specific Phosphorylation of IκBα by a Novel Ubiquitination-Dependent Protein Kinase Activity , 1996, Cell.
[22] R. Davis,et al. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway , 1996, Molecular and cellular biology.
[23] Z. Cao,et al. IRAK: A Kinase Associated with the Interleukin-1 Receptor , 1996, Science.
[24] A. Hershko,et al. Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates. , 1985, Biochemical and biophysical research communications.