Retinal optical coherence tomography image enhancement via shrinkage denoising using double-density dual-tree complex wavelet transform

Abstract. Image enhancement of retinal structures, in optical coherence tomography (OCT) scans through denoising, has the potential to aid in the diagnosis of several eye diseases. In this paper, a locally adaptive denoising algorithm using double-density dual-tree complex wavelet transform, a combination of the double-density wavelet transform and the dual-tree complex wavelet transform, is applied to reduce speckle noise in OCT images of the retina. The algorithm overcomes the limitations of commonly used multiple frame averaging technique, namely the limited number of frames that can be recorded due to eye movements, by providing a comparable image quality in significantly less acquisition time equal to an order of magnitude less time compared to the averaging method. In addition, improvements of image quality metrics and 5 dB increase in the signal-to-noise ratio are attained.

[1]  Shahab Chitchian,et al.  Denoising during optical coherence tomography of the prostate nerves via wavelet shrinkage using dual-tree complex wavelet transform. , 2009, Journal of biomedical optics.

[2]  J. Fujimoto,et al.  Optical Coherence Tomography , 1991, LEOS '92 Conference Proceedings.

[3]  N. Kingsbury Complex Wavelets for Shift Invariant Analysis and Filtering of Signals , 2001 .

[4]  David A. Clausi,et al.  Comprehensive Analysis on the Effects of Noise Estimation Strategies on Image Noise Artifact Suppression Performance , 2011, 2011 IEEE International Symposium on Multimedia.

[5]  Aleksandra Pizurica,et al.  Multiresolution denoising for optical coherence tomography: a review and evaluation , 2008 .

[6]  Eero P. Simoncelli,et al.  Image quality assessment: from error visibility to structural similarity , 2004, IEEE Transactions on Image Processing.

[7]  Ivan W. Selesnick,et al.  The double-density dual-tree DWT , 2004, IEEE Transactions on Signal Processing.

[8]  Joseph M. Schmitt,et al.  Speckle noise reduction for optical coherence tomography , 1998, European Conference on Biomedical Optics.

[9]  M. Sonka,et al.  Retinal Imaging and Image Analysis , 2010, IEEE Reviews in Biomedical Engineering.

[10]  Levent Sendur,et al.  A bivariate shrinkage function for wavelet-based denoising , 2002, 2002 IEEE International Conference on Acoustics, Speech, and Signal Processing.

[11]  Wavelet Based Approach to Multiple-Frame Denoising of OCT-Images , 2010 .

[12]  G. Ripandelli,et al.  Optical coherence tomography. , 1998, Seminars in ophthalmology.

[13]  Joachim Hornegger,et al.  Wavelet denoising of multiframe optical coherence tomography data , 2012, Biomedical optics express.

[14]  Göran Salomonsson,et al.  Image enhancement based on a nonlinear multiscale method , 1997, IEEE Trans. Image Process..

[15]  J. Fujimoto,et al.  Speckle reduction in optical coherence tomography images by use of a spatially adaptive wavelet filter. , 2004, Optics letters.