The impact of age on the physical and cellular properties of the human limbal stem cell niche

[1]  Francisco Figueiredo,et al.  13 years of cultured limbal epithelial cell therapy: A review of the outcomes , 2011, Journal of cellular biochemistry.

[2]  A. Shortt,et al.  Ex vivo cultured limbal epithelial transplantation. A clinical perspective. , 2010, The ocular surface.

[3]  J. Daniels,et al.  Characterisation and functional features of a spontaneously immortalised human corneal epithelial cell line with progenitor-like characteristics , 2010, Brain Research Bulletin.

[4]  T. Marshak,et al.  Ageing of the spermatogenesis system , 2010, Biology Bulletin.

[5]  G. van Zant,et al.  Age-related changes in niche cells influence hematopoietic stem cell function. , 2010, Cell stem cell.

[6]  Gerd Kempermann,et al.  Murine Features of Neurogenesis in the Human Hippocampus across the Lifespan from 0 to 100 Years , 2010, PloS one.

[7]  D. Schaffer,et al.  Relative roles of TGF-β1 and Wnt in the systemic regulation and aging of satellite cell responses , 2009, Aging cell.

[8]  I. Conboy,et al.  Differentiation rather than aging of muscle stem cells abolishes their telomerase activity , 2009, Biotechnology progress.

[9]  I. Cree,et al.  Epidemiological characteristics, predisposing factors and microbiological profiles of infectious corneal ulcers: the Portsmouth corneal ulcer study , 2009, British Journal of Ophthalmology.

[10]  V. Jhanji,et al.  Clinical review of corneal ulcers resulting in evisceration and enucleation in elderly population , 2009, Graefe's Archive for Clinical and Experimental Ophthalmology.

[11]  A. Bernad,et al.  Age‐Dependent Depletion of Human Skin‐Derived Progenitor Cells , 2009, Stem cells.

[12]  K. Nielsen,et al.  Tissue context-activated telomerase in human epidermis correlates with little age-dependent telomere loss. , 2009, Biochimica et biophysica acta.

[13]  L. Tang,et al.  Loss of proliferation and differentiation capacity of aged human periodontal ligament stem cells and rejuvenation by exposure to the young extrinsic environment. , 2009, Tissue engineering. Part A.

[14]  M. Fuller,et al.  Centrosome misorientation reduces stem cell division during ageing , 2008, Nature.

[15]  A. Ho,et al.  Aging of hematopoietic stem cells is regulated by the stem cell niche , 2008, Experimental Gerontology.

[16]  J. V. van Rooij,et al.  Age-related Risk Factors, Culture Outcomes, and Prognosis in Patients Admitted With Infectious Keratitis to Two Dutch Tertiary Referral Centers , 2008, Cornea.

[17]  Rui Zhao,et al.  Age‐related changes of germline stem cell activity, niche signaling activity and egg production in Drosophila , 2008, Aging cell.

[18]  Jianjiang Xu,et al.  Age-related Changes of Human Limbus on In Vivo Confocal Microscopy , 2008, Cornea.

[19]  S. MacNeil,et al.  A xenobiotic-free culture system for human limbal epithelial stem cells. , 2007, Regenerative medicine.

[20]  Monica Boyle,et al.  Decline in self-renewal factors contributes to aging of the stem cell niche in the Drosophila testis. , 2007, Cell stem cell.

[21]  Gerald B Call,et al.  Stem cell aging is controlled both intrinsically and extrinsically in the Drosophila ovary. , 2007, Cell stem cell.

[22]  G. A. Limb,et al.  Transplantation of ex vivo cultured limbal epithelial stem cells: a review of techniques and clinical results. , 2007, Survey of ophthalmology.

[23]  Irving L. Weissman,et al.  Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age , 2007, Nature.

[24]  A. Shortt,et al.  Characterization of the Limbal Epithelial Stem Cell Niche: Novel Imaging Techniques Permit In Vivo Observation and Targeted Biopsy of Limbal Epithelial Stem Cells , 2007, Stem cells.

[25]  M. Gunzer,et al.  Stem Cells, Aging, Niche, Adhesion and Cdc42: A Model for Changes in Cell-Cell Interactions and Hematopoietic Stem Cell Aging , 2007, Cell cycle.

[26]  D. Bonnet,et al.  Age‐Dependent Increase in Side Population Distribution Within Hematopoiesis: Implications for Our Understanding of the Mechanism of Aging , 2007, Stem cells.

[27]  K. Tsubota,et al.  Cytokeratin 15 can be used to identify the limbal phenotype in normal and diseased ocular surfaces. , 2006, Investigative ophthalmology & visual science.

[28]  P. Thomas,et al.  Microbial keratitis at extremes of age. , 2006, Cornea.

[29]  R. Brinster,et al.  Effects of Aging and Niche Microenvironment on Spermatogonial Stem Cell Self‐Renewal , 2006, Stem cells.

[30]  J. Conover,et al.  The aging neurogenic subventricular zone , 2006, Aging cell.

[31]  T. Okano,et al.  Limbal Epithelial Side‐Population Cells Have Stem Cell–Like Properties, Including Quiescent State , 2006, Stem cells.

[32]  U. Schlötzer-Schrehardt,et al.  Identification and characterization of limbal stem cells. , 2005, Experimental eye research.

[33]  E. Di Iorio,et al.  Isoforms of DeltaNp63 and the migration of ocular limbal cells in human corneal regeneration. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[34]  V. Shanmuganathan,et al.  Limbal epithelial crypts: a novel anatomical structure and a putative limbal stem cell niche , 2005, British Journal of Ophthalmology.

[35]  J. Zieske,et al.  The corneal epithelial stem cell niche. , 2005, The ocular surface.

[36]  T. Okano,et al.  Human limbal epithelium contains side population cells expressing the ATP‐binding cassette transporter ABCG2 , 2004, FEBS letters.

[37]  Nicky Lai,et al.  Clinical Ophthalmology: A Systematic Approach, 5th ed. , 2004 .

[38]  M. Boulton,et al.  Stem cells in the eye. , 2004, The international journal of biochemistry & cell biology.

[39]  S. Tseng Regulation and clinical implications of corneal epithelial stem cells , 2004, Molecular Biology Reports.

[40]  R. Cawthon,et al.  Association between telomere length in blood and mortality in people aged 60 years or older , 2003, The Lancet.

[41]  P. Khaw,et al.  Corneal stem cells in review , 2001, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[42]  C. Harley,et al.  Differential Expression of Telomerase Activity in Hematopoietic Progenitors from Adult Human Bone Marrow , 1996, Stem cells.

[43]  Irving L. Weissman,et al.  Stem cells [14] , 1991 .

[44]  J. Kanski Clinical Ophthalmology: A Systematic Approach , 1989 .

[45]  Y. Barrandon,et al.  Three clonal types of keratinocyte with different capacities for multiplication. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[46]  Shaughnessy Sl,et al.  A 'clinical perspective'. , 1977 .