The association between flow and oxygenation and cortical development in fetuses with congenital heart defects using a brain‐age prediction algorithm

Presumably, changes in fetal circulation contribute to the delay in maturation of the cortex in fetuses with congenital heart defect (CHD). The aim of the current study is to analyze fetal brain development based on hemodynamic differences, using novel brain‐age prediction software.

[1]  A. Papageorghiou,et al.  Cortical development in fetuses with congenital heart defects using an automated brain‐age prediction algorithm , 2019, Acta obstetricia et gynecologica Scandinavica.

[2]  Onur Afacan,et al.  Early-Emerging Sulcal Patterns Are Atypical in Fetuses with Congenital Heart Disease. , 2018, Cerebral cortex.

[3]  L. Sleeper,et al.  Early hemodynamic changes after fetal aortic stenosis valvuloplasty predict biventricular circulation at birth , 2018, Prenatal diagnosis.

[4]  Daniel Rueckert,et al.  Impaired development of the cerebral cortex in infants with congenital heart disease is correlated to reduced cerebral oxygen delivery , 2017, Scientific Reports.

[5]  Steffen Ringgaard,et al.  Cerebral Oxygenation Measurements by Magnetic Resonance Imaging in Fetuses With and Without Heart Defects , 2017, Circulation. Cardiovascular imaging.

[6]  J. Dudink,et al.  Prenatal influence of congenital heart defects on trajectories of cortical folding of the fetal brain using three‐dimensional ultrasound , 2017, Prenatal diagnosis.

[7]  C. V. van El,et al.  Implementing non-invasive prenatal testing for aneuploidy in a national healthcare system: global challenges and national solutions , 2017, BMC Health Services Research.

[8]  Y. Ville,et al.  ISUOG consensus statement on current understanding of the association of neurodevelopmental delay and congenital heart disease: impact on prenatal counseling , 2017, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[9]  Qinghai Peng,et al.  Reduced fetal brain fissures depth in fetuses with congenital heart diseases , 2016, Prenatal diagnosis.

[10]  N. Blom,et al.  Head growth in fetuses with isolated congenital heart defects: lack of influence of aortic arch flow and ascending aorta oxygen saturation , 2016, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[11]  E. Gratacós,et al.  Longitudinal changes in fetal biometry and cerebroplacental hemodynamics in fetuses with congenital heart disease , 2016, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[12]  N. Blom,et al.  Prenatal diagnosis of congenital heart defects: accuracy and discrepancies in a multicenter cohort , 2016, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[13]  Steven P. Miller,et al.  Association of Prenatal Diagnosis of Critical Congenital Heart Disease With Postnatal Brain Development and the Risk of Brain Injury. , 2016, JAMA pediatrics.

[14]  N. Bargalló,et al.  Mid‐gestation brain Doppler and head biometry in fetuses with congenital heart disease predict abnormal brain development at birth , 2016, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[15]  M. Donofrio,et al.  3-D volumetric MRI evaluation of the placenta in fetuses with complex congenital heart disease. , 2015, Placenta.

[16]  S. Emani,et al.  Prenatal diagnosis of transposition of the great arteries over a 20‐year period: improved but imperfect , 2015, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[17]  M. Donofrio,et al.  Neurodevelopmental Outcomes After Cardiac Surgery in Infancy , 2015, Pediatrics.

[18]  Steven P. Miller,et al.  Reduced Fetal Cerebral Oxygen Consumption Is Associated With Smaller Brain Size in Fetuses With Congenital Heart Disease , 2015, Circulation.

[19]  J. Alison Noble,et al.  Learning-based prediction of gestational age from ultrasound images of the fetal brain , 2015, Medical Image Anal..

[20]  D. Altman,et al.  International standards for fetal growth based on serial ultrasound measurements: the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project , 2014, The Lancet.

[21]  M. Donofrio,et al.  Prevalence and Spectrum of In Utero Structural Brain Abnormalities in Fetuses with Complex Congenital Heart Disease , 2014, American Journal of Neuroradiology.

[22]  I. Jambaqué,et al.  Executive Functions Development in 5- to 7-Year-Old Children With Transposition of the Great Arteries: A Longitudinal Study , 2014, Developmental neuropsychology.

[23]  Alan C. Evans,et al.  Delayed cortical development in fetuses with complex congenital heart disease. , 2013, Cerebral cortex.

[24]  K. Nicolaides,et al.  Maternal serum placental growth factor at 11–13 weeks' gestation and fetal cardiac defects , 2013, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[25]  Steven P. Miller,et al.  Brain injury and development in newborns with critical congenital heart disease , 2013, Neurology.

[26]  E. Jaeggi,et al.  The association of fetal cerebrovascular resistance with early neurodevelopment in single ventricle congenital heart disease. , 2013, American heart journal.

[27]  Daniela Prayer,et al.  Structural congenital brain disease in congenital heart disease: results from a fetal MRI program. , 2013, European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society.

[28]  K. Kagan,et al.  ISUOG Practice Guidelines: performance of first‐trimester fetal ultrasound scan , 2013, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[29]  Georgina Peacock,et al.  Neurodevelopmental Outcomes in Children With Congenital Heart Disease: Evaluation , 2012 .

[30]  J. Newburger,et al.  Early Developmental Outcome in Children With Hypoplastic Left Heart Syndrome and Related Anomalies: The Single Ventricle Reconstruction Trial , 2012, Circulation.

[31]  Ann R Stark,et al.  Brain immaturity is associated with brain injury before and after neonatal cardiac surgery with high-flow bypass and cerebral oxygenation monitoring. , 2010, The Journal of thoracic and cardiovascular surgery.

[32]  Gil Wernovsky,et al.  Brain maturation is delayed in infants with complex congenital heart defects. , 2009, The Journal of thoracic and cardiovascular surgery.

[33]  B. Rosenblatt,et al.  A new look at outcomes of infants with congenital heart disease. , 2009, Pediatric neurology.

[34]  D. Shera,et al.  Preoperative cerebral blood flow is diminished in neonates with severe congenital heart defects. , 2004, The Journal of thoracic and cardiovascular surgery.

[35]  Robert A. Zimmerman,et al.  An MRI Study of Neurological Injury Before and After Congenital Heart Surgery , 2002, Circulation.

[36]  Leo Breiman,et al.  Random Forests , 2001, Machine Learning.

[37]  G. Vingerhoets,et al.  Neurocognitive development and behaviour in school-aged children after surgery for univentricular or biventricular congenital heart disease. , 2016, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[38]  Alan C. Evans,et al.  Quantitative in vivo MRI measurement of cortical development in the fetus , 2011, Brain Structure and Function.