GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes

[1]  Bryan S. Ho,et al.  Insulin‐induced hypoglycaemia suppresses pulsatile luteinising hormone secretion and arcuate Kiss1 cell activation in female mice , 2019, Journal of neuroendocrinology.

[2]  M. Lawson,et al.  SRXN1 is Necessary for Resolution of GnRH-induced Oxidative Stress and Induction of Gonadotropin Gene Expression. , 2019, Endocrinology.

[3]  M. Lawson,et al.  The RNA-binding Protein ELAVL1 Regulates GnRH Receptor Expression and the Response to GnRH. , 2019, Endocrinology.

[4]  S. Sealfon,et al.  Cytogenetic, Genomic, and Functional Characterization of Pituitary Gonadotrope Cell Lines , 2019, Journal of the Endocrine Society.

[5]  P. Mellon,et al.  The Contribution of the Circadian Gene Bmal1 to Female Fertility and the Generation of the Preovulatory Luteinizing Hormone Surge , 2019, Journal of the Endocrine Society.

[6]  B. Ellsworth,et al.  Single-Cell RNA Sequencing Reveals Novel Markers of Male Pituitary Stem Cells and Hormone-Producing Cell Types , 2018, Endocrinology.

[7]  C. Clay,et al.  Subplasmalemmal hydrogen peroxide triggers calcium influx in gonadotropes , 2018, The Journal of Biological Chemistry.

[8]  T. Shlomi,et al.  Sensitivity of pituitary gonadotropes to hyperglycemia leads to epigenetic aberrations and reduced follicle‐stimulating hormone levels , 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[9]  S. Sealfon,et al.  Regulatory Architecture of the LβT2 Gonadotrope Cell Underlying the Response to Gonadotropin-Releasing Hormone , 2018, Front. Endocrinol..

[10]  M. Lawson,et al.  Induction of Stress Signaling In Vitro and Suppression of Gonadotropin Secretion by Free Fatty Acids in Female Mouse Gonadotropes , 2018, Endocrinology.

[11]  M. Lawson,et al.  Reactive Oxygen Species Link Gonadotropin-Releasing Hormone Receptor Signaling Cascades in the Gonadotrope , 2017, Front. Endocrinol..

[12]  L. Cantley,et al.  Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin. , 2017, Cell reports.

[13]  A. Kauffman,et al.  Effects of Selective Deletion of Tyrosine Hydroxylase from Kisspeptin Cells on Puberty and Reproduction in Male and Female Mice , 2017, eNeuro.

[14]  D. Lauffenburger,et al.  Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis , 2017, PloS one.

[15]  R. Naftalin.  Faculty Opinions recommendation of Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876. , 2017 .

[16]  A. Navratil,et al.  The F0F1 ATP Synthase Complex Localizes to Membrane Rafts in Gonadotrope Cells. , 2016, Molecular endocrinology.

[17]  H. Abdennebi,et al.  Involvement of AMP-activated protein kinase in the protective effectof melatonin against renal ischemia reperfusion injury , 2016 .

[18]  J. Walter,et al.  Molecular Plasticity of Male and Female Murine Gonadotropes Revealed by mRNA Sequencing. , 2016, Endocrinology.

[19]  J. Kristesashvili,et al.  Types of reproductive disorders in underweight and overweight young females and correlations of respective hormonal changes with BMI , 2015, Iranian journal of reproductive medicine.

[20]  J. Kristesashvili,et al.  Peculiarities of sexual development and reproductive function in young women with childhood onset weight problems. , 2014, Georgian medical news.

[21]  J. Rathmell,et al.  The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function. , 2014, Cell metabolism.

[22]  M. Lawson,et al.  Translational control of gene expression in the gonadotrope , 2014, Molecular and Cellular Endocrinology.

[23]  Daniel E. Warren,et al.  Role of GLUT1 in regulation of reactive oxygen species , 2014, Redox biology.

[24]  A. Kauffman,et al.  Analysis of Multiple Positive Feedback Paradigms Demonstrates a Complete Absence of LH Surges and GnRH Activation in Mice Lacking Kisspeptin Signaling1 , 2013, Biology of reproduction.

[25]  B. Thorens,et al.  The SLC2 (GLUT) family of membrane transporters. , 2013, Molecular aspects of medicine.

[26]  A. Shaywitz,et al.  AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1. , 2013, Molecular cell.

[27]  J. Andrade,et al.  AMP-activated protein kinase is a key intermediary in GnRH-stimulated LHβ gene transcription. , 2013, Molecular endocrinology.

[28]  O. Rønnekleiv,et al.  mRNA expression of ion channels in GnRH neurons: Subtype-specific regulation by 17β-estradiol , 2013, Molecular and Cellular Endocrinology.

[29]  S. Sealfon,et al.  β-catenin regulates GnRH-induced FSHβ gene expression. , 2013, Molecular endocrinology.

[30]  G. Kaur,et al.  Intermittent Fasting Dietary Restriction Regimen Negatively Influences Reproduction in Young Rats: A Study of Hypothalamo-Hypophysial-Gonadal Axis , 2013, PloS one.

[31]  Charlotte Avet,et al.  Decoding high Gonadotropin-releasing hormone pulsatility: a role for GnRH receptor coupling to the cAMP pathway? , 2012, Front. Endocrin..

[32]  Shiyong Wu,et al.  A Small-Molecule Inhibitor of Glucose Transporter 1 Downregulates Glycolysis, Induces Cell-Cycle Arrest, and Inhibits Cancer Cell Growth In Vitro and In Vivo , 2012, Molecular Cancer Therapeutics.

[33]  A. Abou-Samra,et al.  GnRH increases glucose transporter-1 expression and stimulates glucose uptake in the gonadotroph. , 2012, The Journal of endocrinology.

[34]  Matko Bosnjak,et al.  REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms , 2011, PloS one.

[35]  M. Thieulant,et al.  Sustained Gonadotropin-Releasing Hormone Stimulation Mobilizes the cAMP/PKA Pathway to Induce Nitric Oxide Synthase Type 1 Expression in Rat Pituitary Cells In Vitro and In Vivo at Proestrus1 , 2010, Biology of reproduction.

[36]  N. Webster,et al.  GnRH pulsatility, the pituitary response and reproductive dysfunction. , 2009, Endocrine journal.

[37]  D. Haisenleder,et al.  Regulation of Intracellular Signaling Cascades by GNRH Pulse Frequency in the Rat Pituitary: Roles for CaMK II, ERK, and JNK Activation1 , 2008, Biology of reproduction.

[38]  P. J. Malcolm,et al.  Evidence for insulin suppression of baseline luteinizing hormone in women with polycystic ovarian syndrome and normal women. , 2008, The Journal of clinical endocrinology and metabolism.

[39]  J. Soh,et al.  Gonadotropin-Releasing Hormone Couples to 3′,5′-Cyclic Adenosine-5′-Monophosphate Pathway through Novel Protein Kinase Cδ and -ε in LβT2 Gonadotrope Cells , 2007 .

[40]  N. Webster,et al.  Pulse sensitivity of the luteinizing hormone beta promoter is determined by a negative feedback loop Involving early growth response-1 and Ngfi-A binding protein 1 and 2. , 2007, Molecular endocrinology.

[41]  B. Kahn,et al.  Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. , 2006, The Journal of clinical investigation.

[42]  S. Stojilkovic,et al.  Roles of purinergic P2X receptors as pacemaking channels and modulators of calcium-mobilizing pathway in pituitary gonadotrophs. , 2006, Molecular endocrinology.

[43]  Janet E Hall,et al.  Inverse relationship between luteinizing hormone and body mass index in polycystic ovarian syndrome: investigation of hypothalamic and pituitary contributions. , 2006, The Journal of clinical endocrinology and metabolism.

[44]  S. Rhind,et al.  Hypothalamic responses to peripheral glucose infusion in food-restricted sheep are influenced by photoperiod. , 2005, The Journal of endocrinology.

[45]  R. Rey,et al.  Acute regulation of translation initiation by gonadotropin-releasing hormone in the gonadotrope cell line LbetaT2. , 2004, Molecular endocrinology.

[46]  L. Halvorson,et al.  The cAMP signaling system regulates LHbeta gene expression: roles of early growth response protein-1, SP1 and steroidogenic factor-1. , 2004, Journal of molecular endocrinology.

[47]  N. Ruderman,et al.  Glucose autoregulates its uptake in skeletal muscle: involvement of AMP-activated protein kinase. , 2003, Diabetes.

[48]  A. Schürmann,et al.  Targeting of GLUT6 (formerly GLUT9) and GLUT8 in rat adipose cells. , 2001, The Biochemical journal.

[49]  S. Stojilkovic,et al.  Signaling by extracellular nucleotides in anterior pituitary cells , 2001, Trends in Endocrinology & Metabolism.

[50]  E. Markus,et al.  Effects of mild food deprivation on the estrous cycle of rats , 2001, Physiology & Behavior.

[51]  I. Svendsen,et al.  The effects of G418 on the growth and metabolism of recombinant mammalian cell lines , 2001, Cytotechnology.

[52]  Ying Cui,et al.  GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[53]  M. Uldry,et al.  GLUTX1, a Novel Mammalian Glucose Transporter Expressed in the Central Nervous System and Insulin-sensitive Tissues* , 2000, The Journal of Biological Chemistry.

[54]  H. Tsukamura,et al.  Glucose Availability Modulates the Timing of the Luteinizing Hormone Surge in the Ewe , 1998, Journal of neuroendocrinology.

[55]  H. Tsukamura,et al.  Reduction of glucose availability suppresses pulsatile luteinizing hormone release in female and male rats. , 1996, Endocrinology.

[56]  J. Jameson,et al.  Roles of estrogen, progesterone, and gonadotropin-releasing hormone (GnRH) in the control of pituitary GnRH receptor gene expression at the time of the preovulatory gonadotropin surges. , 1995, Endocrinology.

[57]  S. Ohkura,et al.  Involvement of ovarian steroids and endogenous opioids in the fasting-induced suppression of pulsatile LH release in ovariectomized rats. , 1991, The Journal of endocrinology.

[58]  J. Windle,et al.  Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice. , 1990, Molecular endocrinology.

[59]  R. Farese,et al.  Glucose‐induced synthesis of diacylglycerol de novo is associated with translocation (activation) of protein kinase C in rat adipocytes , 1989, FEBS letters.

[60]  M. Jutisz,et al.  Cyclic adenosine monophosphate and phorbol ester, like gonadotropin-releasing hormone, stimulate the biosynthesis of luteinizing hormone polypeptide chains in a nonadditive manner. , 1989, Molecular endocrinology.

[61]  L. M. Rutter,et al.  Hypoglycemia alters pulsatile luteinizing hormone secretion in the postpartum beef cow. , 1987, Journal of animal science.

[62]  J. Marshall,et al.  Pituitary LH responsiveness to GnRH in vitro as related to GnRH receptor number. , 1984, The American journal of physiology.

[63]  A. Barkan,et al.  Pituitary gonadotropin-releasing hormone receptors during gonadotropin surges in ovariectomized-estradiol-treated rats. , 1983, Endocrinology.

[64]  J. Marshall,et al.  Pituitary gonadotropin-releasing hormone receptors during the rat estrous cycle. , 1980, Science.

[65]  S. Mccann,et al.  Changes in adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate concentrations in the anterior pituitary and hypothalamus during the rat estrous cycle and effects of administration of sodium pentobarbital in proestrus. , 1980, Endocrinology.

[66]  R. Eckel,et al.  Omega-3 Fatty Acid Supplementation Lowers Serum FSH in Normal Weight But Not Obese Women. , 2016, The Journal of clinical endocrinology and metabolism.

[67]  C. Buggs-Saxton,et al.  Regulation of Glucose Transporter 1 (Slc2a1) in the Pituitary Gonadotrope of Mice after Puberty , 2013 .

[68]  M. Lawson,et al.  GNRH induces the unfolded protein response in the LbetaT2 pituitary gonadotrope cell line. , 2009, Molecular endocrinology.

[69]  J. Soh,et al.  Gonadotropin-releasing hormone couples to 3',5'-cyclic adenosine-5'-monophosphate pathway through novel protein kinase Cdelta and -epsilon in LbetaT2 gonadotrope cells. , 2007, Endocrinology.

[70]  L. Landi,et al.  ROS production and Glut1 activity in two human megakaryocytic cell lines , 2004, BioFactors.