Mathematical Modelling and Simulation Research of Thermal Engraving Technology Based on PMMA Material

We proposed a thermal engraving technology based on heat transfer theory and polymer rheology in microfluidic field. Then, we established a 3D model of the thermal engraving process based on polymethyl methacrylate (PMMA) material. We could employ the model to analyze the influence of temperature and speed on microchannel processing through the finite element simulation. Thus, we gained the optimal processing parameters. The orthogonal experiments were carried out within the parameter ranges obtained by the simulation results. Finally, we fabricated the smooth microchannel, the average roughness of which was 0.3 μm, by using the optimal parameters. Furthermore, we examined the surface morphology and wettability. Our work provides a convenient technological support for a fast, low-cost, and large-scale manufacturing method of microfluidic chips.

[1]  Kun Lian,et al.  Microfluidic devices fabricated in poly(methyl methacrylate) using hot-embossing with integrated sampling capillary and fiber optics for fluorescence detection. , 2002, Lab on a chip.

[2]  C. Chung,et al.  On the fabrication of minimizing bulges and reducing the feature dimensions of microchannels using novel CO2 laser micromachining , 2011 .

[3]  Changyu Shen,et al.  Scale effect on filling stage in micro-injection molding for thin slit cavities , 2012 .

[4]  Roberto Osellame,et al.  Solvent vapor treatment controls surface wettability in PMMA femtosecond-laser-ablated microchannels , 2013 .

[5]  H. N. Hansen,et al.  Characterisation and analysis of microchannels and submicrometre surface roughness of injection moulded microfluidic systems using optical metrology , 2012 .

[6]  P. Heydari,et al.  Low cost method for hot embossing of microstructures on PMMA by SU-8 masters , 2014 .

[7]  Li Tian,et al.  Design and Simulation of Photoelectric Detection Circuit for Microfluidics Chip , 2013 .

[8]  Rafael J. Taboryski,et al.  Fabrication and characterization of injection molded multi level nano and microfluidic systems , 2013 .

[9]  Lin Yuanhui,et al.  フォトレジスト上のパリレンC(POP):ポリマー/金属ナノワイヤ製造のための低温スペーサ技術 , 2011 .

[10]  Z. Wen,et al.  Characterization of a capacitance-coupled contactless conductivity detection system with sidewall electrodes on a low-voltage-driven electrophoresis microchip , 2010, Analytical and bioanalytical chemistry.

[11]  T. Özel,et al.  Effect of Fluence and Pulse Overlapping on Fabrication of Microchannels in PMMA/PDMS Via UV Laser Micromachining: Modeling and Experimentation , 2015 .

[12]  C. Yi,et al.  A single low-cost microfabrication approach for polymethylmethacrylate, polystyrene, polycarbonate and polysulfone based microdevices , 2015 .

[13]  Viscosity measurement of organic glasses below and above glass transition temperature , 2001 .

[14]  Giovanni Tantussi,et al.  Experimental approach to the laser machining of PMMA substrates for the fabrication of microfluidic devices , 2011 .

[15]  Tien-Li Chang.  Micromachining of microfluidic channels in glass by microjoule femtosecond laser pulses , 2013 .

[16]  Antje J. Baeumner,et al.  Design and fabrication of a microfluidic device for near-single cell mRNA isolation using a copper hot embossing master , 2009 .

[17]  Li Tian,et al.  Design of Pre-Amplifiers for Photoelectric Detector , 2013 .

[18]  S. Prakash,et al.  Profile and depth prediction in single-pass and two-pass CO2 laser microchanneling processes , 2015 .