Altered gene expression and neuropathology in Alzheimer's disease

[1]  S. McWeeney,et al.  Mapping cellular transcriptosomes in autopsied Alzheimer's disease subjects and relevant animal models , 2006, Neurobiology of Aging.

[2]  H. Steinbusch,et al.  Age-related loss of synaptophysin immunoreactive presynaptic boutons within the hippocampus of APP751SL, PS1M146L, and APP751SL/PS1M146L transgenic mice. , 2005, The American journal of pathology.

[3]  F. Bloom,et al.  Mouse models of human neurodegenerative disorders: requirements for medication development. , 2005, Archives of neurology.

[4]  P. Reddy,et al.  Time‐course of mitochondrial gene expressions in mice brains: implications for mitochondrial dysfunction, oxidative damage, and cytochrome c in aging , 2005, Journal of neurochemistry.

[5]  A. Popp,et al.  Central cholinergic functions in human amyloid precursor protein knock-in/presenilin-1 transgenic mice , 2004, Neuroscience.

[6]  T. Bayer,et al.  A modified β‐amyloid hypothesis: intraneuronal accumulation of the β‐amyloid peptide – the first step of a fatal cascade , 2004, Journal of neurochemistry.

[7]  T. Bayer,et al.  Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model. , 2004, The American journal of pathology.

[8]  J. Morrison,et al.  The aging brain: morphomolecular senescence of cortical circuits , 2004, Trends in Neurosciences.

[9]  I. Kohane,et al.  Gene regulation and DNA damage in the ageing human brain , 2004, Nature.

[10]  M. Tabaton,et al.  Microarray Analysis in Alzheimer's Disease and Normal Aging , 2004, IUBMB life.

[11]  W. Lukiw Gene Expression Profiling in Fetal, Aged, and Alzheimer Hippocampus: A Continuum of Stress-Related Signaling , 2004, Neurochemical Research.

[12]  D. Dickson Building a more perfect beast: APP transgenic mice with neuronal loss. , 2004, The American journal of pathology.

[13]  H. Steinbusch,et al.  Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease. , 2004, The American journal of pathology.

[14]  R. Shao,et al.  Effects of aging and advanced glycation on gene expression in cerebrum and spleen of mice. , 2003, Biomedical and environmental sciences : BES.

[15]  T. Bayer,et al.  Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice , 2003, Experimental Neurology.

[16]  G. Higgins,et al.  Transgenic mouse models of Alzheimer's disease: phenotype and application , 2003, Behavioural pharmacology.

[17]  H. Steinbusch,et al.  The aging brain: less neurons could be better , 2003, Mechanisms of Ageing and Development.

[18]  H. E. Stanley,et al.  Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[19]  C. Cotman,et al.  The Brain's Microenvironment, Early Functional Loss, and the Conversion to Alzheimer's Disease , 2000, Annals of the New York Academy of Sciences.

[20]  F. Leuven,et al.  Single and multiple transgenic mice as models for Alzheimer’s disease , 2000, Progress in Neurobiology.

[21]  J. Morrison,et al.  Determinants of neuronal vulnerability in neurodegenerative diseases , 1998, Annals of neurology.

[22]  D. Stein,et al.  Greater Metabolic Rate Decreases in Hippocampal Formation and Proisocortex than in Neocortex in Alzheimer’s Disease , 1997, Neuropsychobiology.

[23]  J. Morrison,et al.  Life and death of neurons in the aging brain. , 1997, Science.

[24]  S. Rapoport,et al.  Beta-amyloid induced increase in choline flux across PC12 cell membranes , 1997, Neuroscience Letters.

[25]  S. Gandy,et al.  Importance of vascular changes in selective neurodegeneration with thiamine deficiency. , 1997, Annals of the New York Academy of Sciences.

[26]  Stanley I. Rapoport,et al.  Gene expression of ND4, a subunit of complex I of oxidative phosphorylation in mitochondria, is decreased in temporal cortex of brains of Alzheimer's disease patients , 1996, Brain Research.

[27]  K. Beyreuther,et al.  APP Gene Family Alternative Splicing Generates Functionally Related Isoforms a , 1996, Annals of the New York Academy of Sciences.

[28]  R. Wenthold,et al.  AMPA-selective glutamate receptor subtype immunoreactivity in the entorhinal cortex of non-demented elderly and patients with Alzheimer's disease , 1994, Brain Research.

[29]  S. Rapoport Integrated phylogeny of the primate brain, with special reference to humans and their diseases , 1990, Brain Research Reviews.

[30]  Thomas Arendt,et al.  Alzheimer's disease as a disorder of dynamic brain self-organization. , 2005, Progress in brain research.

[31]  Patrick R Hof,et al.  Selective vulnerability of corticocortical and hippocampal circuits in aging and Alzheimer's disease. , 2002, Progress in brain research.