Fluorescence optical fibre sensor provides accurate continuous oxygen detection in rabbit model with acute lung injury

Background and objective:  Continuous monitoring of PaO2 in seriously ill patients is an important aspect of clinical management, especially for patients with acute lung injury (ALI) or acute respiratory distress syndrome. We have developed a fibreoptic sensor to detect PaO2in vivo based on fluorescence quenching technology. In this study we evaluated the sensitivity of this sensor in monitoring PaO2 in a rabbit model with ALI.

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