Orphanet Journal of Rare Diseases

[1]  D. Isenberg,et al.  Fifty years of anti-ds DNA antibodies: are we approaching journey's end? , 2007, Rheumatology.

[2]  G. Sturfelt,et al.  Glomerular apoptotic nucleosomes are central target structures for nephritogenic antibodies in human SLE nephritis. , 2007, Kidney international.

[3]  B. Volpe,et al.  Human lupus autoantibodies against NMDA receptors mediate cognitive impairment , 2006, Proceedings of the National Academy of Sciences.

[4]  D. Isenberg,et al.  Association of antinucleosome antibodies with disease flare in serologically active clinically quiescent patients with systemic lupus erythematosus. , 2006, Arthritis and rheumatism.

[5]  Mimi Y. Kim,et al.  The effect of moderate-dose corticosteroids in preventing severe flares in patients with serologically active, but clinically stable, systemic lupus erythematosus: findings of a prospective, randomized, double-blind, placebo-controlled trial. , 2006, Arthritis and rheumatism.

[6]  O. Rekvig,et al.  Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis , 2006, Arthritis research & therapy.

[7]  B. Volpe,et al.  Anti-N-methyl-D-aspartate receptor antibodies, cognitive dysfunction, and depression in systemic lupus erythematosus. , 2006, Arthritis and rheumatism.

[8]  O. Rekvig,et al.  Cardiovascular, Pulmonary and Renal Pathology Nephritogenic Lupus Antibodies Recognize Glomerular Basement Membrane-Associated Chromatin Fragments Released from Apoptotic Intraglomerular Cells , 2006 .

[9]  G. Burmester,et al.  Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus , 2006, Arthritis research & therapy.

[10]  D. Isenberg,et al.  Systemic lupus erythematosus—2005 annus mirabilis? , 2006, Nature Clinical Practice Rheumatology.

[11]  T. Yoshio,et al.  Association of IgG anti-NR2 glutamate receptor antibodies in cerebrospinal fluid with neuropsychiatric systemic lupus erythematosus. , 2006, Arthritis and rheumatism.

[12]  R. Voll,et al.  SLE--a disease of clearance deficiency? , 2005, Rheumatology.

[13]  Mimi Y. Kim,et al.  Outcomes of planned home births with certified professional midwives: large prospective study in North America , 2005, BMJ : British Medical Journal.

[14]  J. Kere,et al.  Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. , 2005, American journal of human genetics.

[15]  J. Merrill.  BLyS antagonists and peptide tolerance induction , 2005, Lupus.

[16]  D. Isenberg,et al.  Anti-B cell therapy (rituximab) in the treatment of autoimmune diseases. , 2004, Lupus.

[17]  J. Banchereau,et al.  IFN-alpha induces early lethal lupus in preautoimmune (New Zealand Black x New Zealand White) F1 but not in BALB/c mice. , 2005, Journal of immunology.

[18]  J. Harley,et al.  Genetics of human systemic lupus erythematosus: the emerging picture. , 2004, Current opinion in immunology.

[19]  A. Rahman.  Autoantibodies, lupus and the science of sabotage. , 2004, Rheumatology.

[20]  J. Salmon,et al.  Heparin prevents antiphospholipid antibody–induced fetal loss by inhibiting complement activation , 2004, Nature Medicine.

[21]  M. Aringer,et al.  Safety and efficacy of tumor necrosis factor alpha blockade in systemic lupus erythematosus: an open-label study. , 2004, Arthritis and rheumatism.

[22]  M. Ward.  Prevalence of physician-diagnosed systemic lupus erythematosus in the United States: results from the third national health and nutrition examination survey. , 2004, Journal of women's health.

[23]  Lee Hebert,et al.  The classification of glomerulonephritis in systemic lupus erythematosus revisited. , 2004, Kidney international.

[24]  J. Cameron.  The treatment of lupus nephritis , 1989, Pediatric Nephrology.

[25]  D. Isenberg,et al.  Is alpha-actinin a target for pathogenic anti-DNA antibodies in lupus nephritis? , 2004, Arthritis and rheumatism.

[26]  J. Buyon,et al.  Immunohistologic evidence supports apoptosis, IgG deposition, and novel macrophage/fibroblast crosstalk in the pathologic cascade leading to congenital heart block. , 2004, Arthritis and rheumatism.

[27]  J. Attwood,et al.  Value of MRI of the brain in patients with systemic lupus erythematosus and neurologic disturbance , 2004, Neuroradiology.

[28]  E. Fireman,et al.  Pulmonary disease in systemic lupus erythematosus and the antiphospholpid syndrome. , 2004, Autoimmunity reviews.

[29]  J. Buyon,et al.  Maternal autoantibodies and congenital heart block: mediators, markers, and therapeutic approach. , 2003, Seminars in arthritis and rheumatism.

[30]  V. Roschke,et al.  B lymphocyte stimulator overexpression in patients with systemic lupus erythematosus: longitudinal observations. , 2003, Arthritis and rheumatism.

[31]  V. Roschke,et al.  Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator. , 2003, Arthritis and rheumatism.

[32]  G. Hughes,et al.  Morbidity and Mortality in Systemic Lupus Erythematosus During a 10-Year Period: A Comparison of Early and Late Manifestations in a Cohort of 1,000 Patients , 2003, Medicine.

[33]  M. Wener,et al.  Multiple autoantibodies form the glomerular immune deposits in patients with systemic lupus erythematosus. , 2003, The Journal of rheumatology.

[34]  C. Lau,et al.  Pathogenesis of systemic lupus erythematosus , 2003, Journal of clinical pathology.

[35]  B. Vanderhyden,et al.  Focal and Segmental Glomerulosclerosis in Mice with Podocyte-Specific Expression of Mutant α-Actinin-4 , 2003 .

[36]  E. D. De Jong,et al.  Deposition of nucleosomal antigens (histones and DNA) in the epidermal basement membrane in human lupus nephritis. , 2003, Arthritis and rheumatism.

[37]  G. Karypis,et al.  Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[38]  R. Bagin,et al.  LJP 394 for the prevention of renal flare in patients with systemic lupus erythematosus: results from a randomized, double-blind, placebo-controlled study. , 2003, Arthritis and rheumatism.

[39]  D. Isenberg,et al.  Prevalence, patterns of disease and outcome in patients with systemic lupus erythematosus who develop severe haematological problems. , 2003, Rheumatology.

[40]  L. Rönnblom,et al.  Systemic lupus erythematosus and the type I interferon system , 2003, Arthritis research & therapy.

[41]  S. Luo,et al.  Dehydroepiandrosterone treatment of women with mild-to-moderate systemic lupus erythematosus: a multicenter randomized, double-blind, placebo-controlled trial. , 2002, Arthritis and rheumatism.

[42]  D. Isenberg,et al.  An open study of B lymphocyte depletion in systemic lupus erythematosus. , 2002, Arthritis and rheumatism.

[43]  Y. Levy,et al.  Immunosuppressive therapy in lupus nephritis: the Euro-Lupus Nephritis Trial, a randomized trial of low-dose versus high-dose intravenous cyclophosphamide. , 2002, Arthritis and rheumatism.

[44]  M. Walport.  Complement and systemic lupus erythematosus , 2002, Arthritis research.

[45]  D. Isenberg,et al.  Outcome of a cohort of 300 patients with systemic lupus erythematosus attending a dedicated clinic for over two decades , 2002, Annals of the rheumatic diseases.

[46]  C. Putterman,et al.  Alpha-actinin is a cross-reactive renal target for pathogenic anti-DNA antibodies. , 2002, Journal of immunology.

[47]  G. Ferraccioli,et al.  Drug-induced systemic lupus erythematosus and TNF-alpha blockers. , 2002, Lancet.

[48]  M. Petri,et al.  Catastrophic Antiphospholipid Syndrome: Clues to the Pathogenesis from a Series of 80 Patients , 2001, Medicine.

[49]  T. Behrens,et al.  Delineating the genetic basis of systemic lupus erythematosus. , 2001, Immunity.

[50]  E. Wakeland,et al.  The genetics of lupus , 2001, Current opinion in nephrology and hypertension.

[51]  M. Monestier,et al.  Lupus anti‐DNA autoantibodies cross‐react with a glomerular structural protein: a case for tissue injury by molecular mimicry , 2001, European journal of immunology.

[52]  D. Isenberg,et al.  Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis. , 2001, The New England journal of medicine.

[53]  M. Feldmann,et al.  Assessment of antibodies to double-stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor necrosis factor alpha: findings in open-label and randomized placebo-controlled trials. , 2000, Arthritis and rheumatism.

[54]  D. D'cruz,et al.  The prevalence and associations of fatigue in systemic lupus erythematosus. , 2000, Rheumatology.

[55]  M. Zhu,et al.  Functional analyses of patient-derived IgG monoclonal anticardiolipin antibodies using in vivo thrombosis and in vivo microcirculation models. , 2000, Thrombosis and haemostasis.

[56]  D. Alarcón-Segovia,et al.  Clinical and biologic effects of anti-interleukin-10 monoclonal antibody administration in systemic lupus erythematosus. , 2000, Arthritis and rheumatism.

[57]  K. Sullivan,et al.  Genetics of systemic lupus erythematosus. Clinical implications. , 2000, Rheumatic diseases clinics of North America.

[58]  J. Bach,et al.  Presence of antinucleosome autoantibodies in a restricted set of connective tissue diseases: antinucleosome antibodies of the IgG3 subclass are markers of renal pathogenicity in systemic lupus erythematosus. , 2000, Arthritis and rheumatism.

[59]  C. Lau,et al.  Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis. Hong Kong-Guangzhou Nephrology Study Group. , 2000, The New England journal of medicine.

[60]  Y Ioannou,et al.  A review of gastrointestinal manifestations of systemic lupus erythematosus. , 1999, Rheumatology.

[61]  L. Lu,et al.  Major peptide autoepitopes for nucleosome-specific T cells of human lupus. , 1999, The Journal of clinical investigation.

[62]  J. Berden,et al.  Role of nucleosomes for induction and glomerular binding of autoantibodies in lupus nephritis. , 1999, Current opinion in nephrology and hypertension.

[63]  Caroline Gordon,et al.  The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes. , 1999, Arthritis and rheumatism.

[64]  M. Ward.  Premature morbidity from cardiovascular and cerebrovascular diseases in women with systemic lupus erythematosus. , 1999, Arthritis and rheumatism.

[65]  Pier Paolo Pandolfi,et al.  Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies , 1998, Nature Genetics.

[66]  Andrew C. R. Martin,et al.  Genetic, structural and functional properties of an IgG DNA‐binding monoclonal antibody from a lupus patient with nephritis , 1998, European journal of immunology.

[67]  J. Harley,et al.  An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. , 1997, The Journal of clinical investigation.

[68]  M. Hochberg,et al.  Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. , 1997, Arthritis and rheumatism.

[69]  M. Monestier,et al.  Antigen specificity of anti‐nuclear antibodies complexed to nucleosomes determines glomerular basement membrane binding in vivo , 1997, European journal of immunology.

[70]  M. Weisman,et al.  Reduction in circulating dsDNA antibody titer after administration of LJP 394. , 1997, The Journal of rheumatology.

[71]  T. Vischer,et al.  Circulating levels of tumor necrosis factor soluble receptors in systemic lupus erythematosus are significantly higher than in other rheumatic diseases and correlate with disease activity. , 1997, The Journal of rheumatology.

[72]  J. Renauld,et al.  Serum interleukin 10 titers in systemic lupus erythematosus reflect disease activity , 1995, Lupus.

[73]  D. Isenberg,et al.  Human IgG anti-DNA antibodies deposit in kidneys and induce proteinuria in SCID mice. , 1995, Kidney international.

[74]  D. Gladman,et al.  Mortality studies in systemic lupus erythematosus. Results from a single center. II. Predictor variables for mortality. , 1995, The Journal of rheumatology.

[75]  C. Gordon,et al.  The prevalence and incidence of systemic lupus erythematosus in Birmingham, England. Relationship to ethnicity and country of birth. , 1995, Arthritis and rheumatism.

[76]  M. Pujol,et al.  High prevalence of platelet autoantibodies in patients with systemic lupus erythematosus , 1995, British journal of haematology.

[77]  B. Diamond,et al.  Mutational analysis of an autoantibody: differential binding and pathogenicity , 1994, The Journal of experimental medicine.

[78]  H. Dijkman,et al.  Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo. , 1994, The Journal of clinical investigation.

[79]  A. Rosen,et al.  Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes , 1994, The Journal of experimental medicine.

[80]  J. Harley,et al.  A distinctive autoantibody profile in black female patients with lupus nephritis. , 1993, Arthritis and rheumatism.

[81]  M. Walport,et al.  Splenic uptake of immune complexes in man is complement-dependent. , 1993, Journal of immunology.

[82]  M. Okamura,et al.  Significance of enzyme linked immunosorbent assay (ELISA) for antibodies to double stranded and single stranded DNA in patients with lupus nephritis: correlation with severity of renal histology. , 1993, Annals of the rheumatic diseases.

[83]  R. Coffman,et al.  Mechanism and regulation of immunoglobulin isotype switching. , 1993, Advances in immunology.

[84]  F. Dove.  Drug-induced lupus , 1982 .

[85]  A. Steinberg,et al.  Controlled trial of pulse methylprednisolone versus two regimens of pulse cyclophosphamide in severe lupus nephritis , 1992, The Lancet.

[86]  S. Avrameas,et al.  Natural autoantibodies: from 'horror autotoxicus' to 'gnothi seauton'. , 1991, Immunology today.

[87]  P. Limburg,et al.  Measurement of increases in anti-double-stranded DNA antibody levels as a predictor of disease exacerbation in systemic lupus erythematosus. A long-term, prospective study. , 1990, Arthritis and rheumatism.

[88]  J. Sánchez-Guerrero,et al.  Antiphospholipid Antibodies and the Antiphospholipid Syndrome in Systemic Lupus Erythematosus A Prospective Analysis of 500 Consecutive Patients , 1989, Medicine.

[89]  H. Mcdevitt,et al.  Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis. , 1988, Nature.

[90]  O. Pankewycz,et al.  Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits. , 1987, Journal of immunology.

[91]  Thomas L. Rothstein,et al.  The role of clonal selection and somatic mutation in autoimmunity , 1987, Nature.

[92]  A. Todd-Pokropek,et al.  Detection of cross-reactive anti-DNA antibody idiotypes in the serum of systemic lupus erythematosus patients and of their relatives. , 1985, Arthritis and rheumatism.

[93]  P. Stastny,et al.  Serologic and HLA associations in subacute cutaneous lupus erythematosus, a clinical subset of lupus erythematosus. , 1982, Annals of internal medicine.

[94]  J F Fries,et al.  The 1982 revised criteria for the classification of systemic lupus erythematosus. , 1982, Arthritis and rheumatism.

[95]  M. Walport,et al.  The immunogenetics of SLE. , 1982, Clinics in rheumatic diseases.

[96]  J. Cameron,et al.  Lupus Nephritis , 1959, Clinics in rheumatic diseases.

[97]  M. Reichlin,et al.  Deposition of antibodies to a soluble cytoplasmic antigen in the kidneys of patients with systemic lupus erythematosus. , 1979, Arthritis and rheumatism.

[98]  M. Urowitz,et al.  The bimodal mortality pattern of systemic lupus erythematosus. , 1976, The American journal of medicine.

[99]  P. Schur,et al.  IMMUNOLOGICAL STUDIES CONCERNING THE NEPHRITIS OF SYSTEMIC LUPUS ERYTHEMATOSUS , 1967, The Journal of experimental medicine.

[100]  M. Merrell,et al.  Determination of prognosis in chronic disease, illustrated by systemic lupus erythematosus. , 1955, Journal of chronic diseases.

[101]  A D GUNN,et al.  Case of Anaphylaxis after Anaesthesia , 1943, British medical journal.