Lung cancer and cyclooxygenase-2.

[1]  J. Lammers,et al.  Results of surgical treatment of T4 non-small cell lung cancer. , 2003, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[2]  R. Shore,et al.  Aspirin and lung cancer in women , 2002, British Journal of Cancer.

[3]  D. Nie,et al.  Cyclooxygenase, lipoxygenase and tumor angiogenesis , 2002, Cellular and Molecular Life Sciences CMLS.

[4]  Xueqin Song,et al.  Cyclooxygenase-2, player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells. , 2002, Journal of the National Cancer Institute.

[5]  M. Brock,et al.  Molecular assessment of lymph nodes in patients with resected stage I non-small cell lung cancer: preliminary results of a prospective study. , 2002, The Journal of thoracic and cardiovascular surgery.

[6]  J. Minna,et al.  Sulindac Enhances Tumor Necrosis Factor-α-mediated Apoptosis of Lung Cancer Cell Lines by Inhibition of Nuclear Factor-κB , 2002 .

[7]  B. Craig,et al.  Effects of the cyclooxygenase inhibitor, piroxicam, on tumor response, apoptosis, and angiogenesis in a canine model of human invasive urinary bladder cancer. , 2002, Cancer research.

[8]  D. Carney Lung cancer--time to move on from chemotherapy. , 2002, The New England journal of medicine.

[9]  Pan‐Chyr Yang,et al.  Cyclooxygenase-2 Inducing Mcl-1-dependent Survival Mechanism in Human Lung Adenocarcinoma CL1.0 Cells , 2001, The Journal of Biological Chemistry.

[10]  H. Vainio Is COX‐2 inhibition a panacea for cancer prevention? , 2001, International journal of cancer.

[11]  M. Pan,et al.  Non‐steroidal anti‐inflammatory drugs inhibit matrix metalloproteinase‐2 expression via repression of transcription in lung cancer cells , 2001, FEBS letters.

[12]  C. Weng,et al.  Cyclooxygenase-2 level and culture conditions influence NS398-induced apoptosis and caspase activation in lung cancer cells. , 2001, Oncology reports.

[13]  H. Choy,et al.  A selective cyclooxygenase-2 inhibitor, NS-398, enhances the effect of radiation in vitro and in vivo preferentially on the cells that express cyclooxygenase-2. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[14]  Y. Miller,et al.  Fluorescence versus white-light bronchoscopy for detection of preneoplastic lesions: a randomized study. , 2001, Journal of the National Cancer Institute.

[15]  M. Spitz,et al.  Lung cancer chemoprevention: an integrated approach. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[16]  A. Grothey,et al.  Cyclooxygenase-2: a novel target for cancer chemotherapy? , 2001, Journal of Cancer Research and Clinical Oncology.

[17]  Li Zhu,et al.  Non-small Cell Lung Cancer Cyclooxygenase-2-dependent Invasion Is Mediated by CD44* , 2001, The Journal of Biological Chemistry.

[18]  S. Lippman,et al.  Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[19]  J. Masferrer,et al.  COX‐2 is expressed in human pulmonary, colonic, and mammary tumors , 2000, Cancer.

[20]  S. Lippman,et al.  15-Lipoxygenase-1 mediates nonsteroidal anti-inflammatory drug-induced apoptosis independently of cyclooxygenase-2 in colon cancer cells. , 2000, Cancer research.

[21]  Y. Hosomi,et al.  Increased cyclooxygenase 2 (COX-2) expression occurs frequently in precursor lesions of human adenocarcinoma of the lung. , 2000, Lung cancer.

[22]  A. Raz,et al.  Indomethacin Inhibits the Accumulation of Tumor Cells in Mouse Lungs and Subsequent Growth of Lung Metastases , 2000, Chemotherapy.

[23]  G. Zimmerman,et al.  Intracellular unesterified arachidonic acid signals apoptosis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[24]  Y. Kawahito,et al.  Meloxicam inhibits the growth of non-small cell lung cancer. , 2000, Anticancer research.

[25]  A. Weeraratna,et al.  Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases. , 2000, Cancer research.

[26]  T. Hla,et al.  Expression of cyclooxygenase‐2 in prostate carcinoma , 2000, Cancer.

[27]  X. Ding,et al.  Blockade of cyclooxygenase-2 inhibits proliferation and induces apoptosis in human pancreatic cancer cells. , 2000, Anticancer research.

[28]  R. Dziadziuszko,et al.  Results of surgical treatment of non-small cell lung cancer: validation of the new postoperative pathologic TNM classification. , 2000, The Journal of thoracic and cardiovascular surgery.

[29]  S. Lippman,et al.  Aspirin induction of apoptosis in esophageal cancer: a potential for chemoprevention. , 2000, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[30]  L. Norton,et al.  Microtubule-interfering Agents Stimulate the Transcription of Cyclooxygenase-2 , 2000, The Journal of Biological Chemistry.

[31]  T. Mitsudomi,et al.  Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

[32]  W. Earnshaw,et al.  Induction of apoptosis by cancer chemotherapy. , 2000, Experimental cell research.

[33]  S. Lippman,et al.  Lung cancer chemoprevention. , 2000, Seminars in surgical oncology.

[34]  K. Seibert,et al.  Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. , 2000, Cancer research.

[35]  D. Nie,et al.  Thromboxane A2 Regulation of Endothelial Cell Migration, Angiogenesis, and Tumor Metastasis☆ , 2000 .

[36]  Li Zhu,et al.  Specific Inhibition of Cyclooxygenase 2 Restores Antitumor Reactivity by Altering the Balance of IL-10 and IL-12 Synthesis1 , 2000, The Journal of Immunology.

[37]  M. You,et al.  Inhibition of COX-2 and induction of apoptosis: two determinants of nonsteroidal anti-inflammatory drugs' chemopreventive efficacies in mouse lung tumorigenesis. , 2000, Experimental lung research.

[38]  Taylor Murray,et al.  Cancer statistics, 2000 , 2000, CA: a cancer journal for clinicians.

[39]  D. Spray,et al.  Inhibition of Endothelial Cell Migration, Intercellular Communication, and Vascular Tube Formation by Thromboxane A2 * , 1999, The Journal of Biological Chemistry.

[40]  T. Oguri,et al.  Cyclooxygenase‐2 (COX‐2) mRNA Expression Levels in Normal Lung Tissues and Non‐small Cell Lung Cancers , 1999, Japanese journal of cancer research : Gann.

[41]  M. Stolina,et al.  T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function. , 1999, Journal of immunology.

[42]  K. Kinzler,et al.  PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs , 1999, Cell.

[43]  G. Piazza,et al.  Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines. , 1999, Biochemical pharmacology.

[44]  R. Langenbach,et al.  Malignant Transformation and Antineoplastic Actions of Nonsteroidal Antiinflammatory Drugs (Nsaids) on Cyclooxygenase-Null Embryo Fibroblasts , 1999, The Journal of experimental medicine.

[45]  Y. Yatabe,et al.  Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

[46]  L. Matrisian,et al.  Differential expression of matrilysin and cyclooxygenase‐2 in intestinal and colorectal neoplasms , 1999, Molecular carcinogenesis.

[47]  A. Castonguay,et al.  Prevention of NNK-induced lung tumorigenesis in A/J mice by acetylsalicylic acid and NS-398. , 1998, Cancer research.

[48]  A. Ristimäki,et al.  Expression of cyclooxygenase-2 in human lung carcinoma. , 1998, Cancer research.

[49]  R. Gaynor,et al.  The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β , 1998, Nature.

[50]  M. Taketo Cyclooxygenase-2 inhibitors in tumorigenesis (Part II). , 1998, Journal of the National Cancer Institute.

[51]  A. Levine,et al.  NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells. , 1998, Cancer research.

[52]  Y. Yatabe,et al.  Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. , 1998, Cancer research.

[53]  P. Lipsky,et al.  Cyclooxygenase in biology and disease , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[54]  R. DuBois,et al.  Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells , 1998, Cell.

[55]  Li Zhu,et al.  Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production. , 1998, Cancer research.

[56]  K. Seibert,et al.  Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. , 1998, Cancer research.

[57]  K. Kinzler,et al.  Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[58]  J. Morrow,et al.  Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. , 1998, Cancer research.

[59]  J. Vane,et al.  Cyclooxygenases 1 and 2. , 1998, Annual review of pharmacology and toxicology.

[60]  C. Paraskeva,et al.  Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression. , 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

[61]  D. Alberts,et al.  Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels. , 1997, Cancer research.

[62]  N. Yoshimi,et al.  Apoptosis Induced by NS‐398, a Selective Cyclooxygenase‐2 Inhibitor, in Human Colorectal Cancer Cell Lines , 1997, Japanese journal of cancer research : Gann.

[63]  C. Mountain,et al.  Revisions in the International System for Staging Lung Cancer. , 1997, Chest.

[64]  R. Muschel,et al.  The molecular regulation of apoptosis and implications for radiation oncology. , 1997, International journal of radiation biology.

[65]  J. Morrow,et al.  Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. , 1997, The Journal of clinical investigation.

[66]  A. Castonguay,et al.  Chemopreventive efficacies of aspirin and sulindac against lung tumorigenesis in A/J mice. , 1997, Carcinogenesis.

[67]  R. DuBois,et al.  Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[68]  V. Grégoire,et al.  Radiation-induced apoptosis in tumors: effect of radiation modulating agents. , 1997, Advances in experimental medicine and biology.

[69]  S. Dubinett,et al.  Non-small cell lung cancer-derived soluble mediators and prostaglandin E2 enhance peripheral blood lymphocyte IL-10 transcription and protein production. , 1996, Journal of immunology.

[70]  Bruno C. Hancock,et al.  Suppression of Intestinal Polyposis in Apc Δ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2) , 1996, Cell.

[71]  B. Rigas,et al.  Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway. , 1996, Biochemical pharmacology.

[72]  M. Bertagnolli,et al.  Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis. , 1996, Cancer research.

[73]  R. DuBois,et al.  Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2 , 1995, Cell.

[74]  D. Reed,et al.  Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclooxygenases in chicken embryo fibroblasts. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[75]  S. Byers,et al.  Role of E-cadherin in the response of tumor cell aggregates to lymphatic, venous and arterial flow: measurement of cell-cell adhesion strength. , 1995, Journal of cell science.

[76]  P. Pasricha,et al.  Inhibition of apoptosis during development of colorectal cancer. , 1995, Cancer research.

[77]  J. Lee,et al.  bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis. , 1995, Cancer research.

[78]  R. Coffey,et al.  Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. , 1994, Gastroenterology.

[79]  R. Everson,et al.  Aspirin Use and Lung, Colon, and Breast Cancer Incidence in a Prospective Study , 1994, Epidemiology.

[80]  Y. Doki,et al.  Correlation between E-cadherin expression and invasiveness in vitro in a human esophageal cancer cell line. , 1993, Cancer research.

[81]  W. Birchmeier,et al.  E-cadherin expression in primary and metastatic gastric cancer: down-regulation correlates with cellular dedifferentiation and glandular disintegration. , 1993, Cancer research.

[82]  V. Winn,et al.  A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein. , 1991, The Journal of biological chemistry.

[83]  B. Varnum,et al.  TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. , 1991, The Journal of biological chemistry.

[84]  H. Herschman Primary response genes induced by growth factors and tumor promoters. , 1991, Annual review of biochemistry.

[85]  W. Waddell,et al.  Sulindac for polyposis of the colon , 1983, Journal of surgical oncology.

[86]  J. Vane,et al.  Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. , 1971, Nature: New biology.