Hepatic HuR modulates lipid homeostasis in response to high-fat diet

[1]  Z. Younossi Non-alcoholic fatty liver disease - A global public health perspective. , 2019, Journal of hepatology.

[2]  Ji Yuan,et al.  Endothelial HuR deletion reduces the expression of proatherogenic molecules and attenuates atherosclerosis , 2018, International immunopharmacology.

[3]  R. Tayyem,et al.  Non-alcoholic fatty liver disease and associated dietary and lifestyle risk factors. , 2018, Diabetes & metabolic syndrome.

[4]  M. Bennett,et al.  Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice , 2018, Aging cell.

[5]  Oliver D. K. Maddocks,et al.  Serine and Functional Metabolites in Cancer. , 2017, Trends in cell biology.

[6]  Marvin N. Wright,et al.  Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice , 2017, bioRxiv.

[7]  M. Gorospe,et al.  RNA-binding proteins regulate cell respiration and coenzyme Q biosynthesis by post-transcriptional regulation of COQ7 , 2016, RNA biology.

[8]  G. Weber Metabolism in cancer metastasis , 2016, International journal of cancer.

[9]  Liying Li,et al.  Essential Roles of RNA-binding Protein HuR in Activation of Hepatic Stellate Cells Induced by Transforming Growth Factor-β1 , 2016, Scientific Reports.

[10]  M. Gorospe,et al.  NSun2 delays replicative senescence by repressing p27 (KIP1) translation and elevating CDK1 translation , 2015, Aging.

[11]  M. Soller,et al.  Concentration and Localization of Coexpressed ELAV/Hu Proteins Control Specificity of mRNA Processing , 2015, Molecular and Cellular Biology.

[12]  E. Levy Insights from human congenital disorders of intestinal lipid metabolism , 2015, Journal of Lipid Research.

[13]  I. Kotta-Loizou,et al.  Clinical significance of HuR expression in human malignancy , 2014, Medical Oncology.

[14]  M. Gorospe,et al.  RNA binding protein HuR regulates the expression of ABCA1[S] , 2014, Journal of Lipid Research.

[15]  Yael Mandel-Gutfreund,et al.  RBPmap: a web server for mapping binding sites of RNA-binding proteins , 2014, Nucleic Acids Res..

[16]  B. Fromenty,et al.  Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease , 2013, Hepatology.

[17]  J. Keene,et al.  Mechanisms coordinating ELAV/Hu mRNA regulons. , 2013, Current opinion in genetics & development.

[18]  Wengong Wang Regulatory RNA-binding proteins in senescence , 2012, Ageing Research Reviews.

[19]  K. Adeli Translational control mechanisms in metabolic regulation: critical role of RNA binding proteins, microRNAs, and cytoplasmic RNA granules. , 2011, American journal of physiology. Endocrinology and metabolism.

[20]  Kotb Abdelmohsen,et al.  Posttranscriptional regulation of cancer traits by HuR , 2010, Wiley interdisciplinary reviews. RNA.

[21]  Shelly C. Lu,et al.  HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis. , 2010, Gastroenterology.

[22]  M. Gorospe,et al.  Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence , 2009, Nucleic acids research.

[23]  Caiying Guo,et al.  Essential role of the RNA-binding protein HuR in progenitor cell survival in mice. , 2009, The Journal of clinical investigation.

[24]  Hirokazu Takahashi,et al.  Dysfunctional very‐low‐density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis , 2009, Hepatology.

[25]  Adrian R Krainer,et al.  Splicing therapeutics in SMN2 and APOB. , 2009, Current opinion in molecular therapeutics.

[26]  F. Bellanti,et al.  Alterations of hepatic ATP homeostasis and respiratory chain during development of non‐alcoholic steatohepatitis in a rodent model , 2008, European journal of clinical investigation.

[27]  J. Weiss,et al.  Thematic review series: Systems Biology Approaches to Metabolic and Cardiovascular Disorders. Network perspectives of cardiovascular metabolism Published, JLR Papers in Press, August 31, 2006. , 2006, Journal of Lipid Research.

[28]  I. Goldberg,et al.  Ins and outs modulating hepatic triglyceride and development of nonalcoholic fatty liver disease. , 2006, Gastroenterology.

[29]  M. Gorospe,et al.  Translational Control of Cytochrome c by RNA-Binding Proteins TIA-1 and HuR , 2006, Molecular and Cellular Biology.

[30]  P. Nilsson-ehle,et al.  Influence of liver cancer on lipid and lipoprotein metabolism , 2006, Lipids in Health and Disease.

[31]  J. Jessurun,et al.  Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. , 2005, The Journal of clinical investigation.

[32]  A. Cederbaum,et al.  A high‐fat diet leads to the progression of non‐alcoholic fatty liver disease in obese rats , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[33]  J. Arenas,et al.  Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis , 2003, Hepatology.

[34]  E. Fisher,et al.  Complexity in the Secretory Pathway: The Assembly and Secretion of Apolipoprotein B-containing Lipoproteins* , 2002, The Journal of Biological Chemistry.

[35]  D. Kardassis,et al.  Transcriptional regulatory mechanisms of the human apolipoprotein genes in vitro and in vivo , 2001, Current opinion in lipidology.

[36]  T Hashimoto,et al.  Defect in Peroxisome Proliferator-activated Receptor α-inducible Fatty Acid Oxidation Determines the Severity of Hepatic Steatosis in Response to Fasting* , 2000, The Journal of Biological Chemistry.

[37]  M Sullivan,et al.  Identification and Characterization of a 315-Base Pair Enhancer, Located More than 55 Kilobases 5′ of the Apolipoprotein B Gene, That Confers Expression in the Intestine* , 2000, The Journal of Biological Chemistry.

[38]  C. Baird The pilot study. , 2000, Orthopedic nursing.

[39]  H. Cortez‐Pinto,et al.  Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. , 1999, JAMA.

[40]  J. Borén,et al.  The assembly and secretion of apolipoprotein B-containing lipoproteins. , 1999, Current opinion in lipidology.

[41]  J. Borén,et al.  Influence of triacylglycerol biosynthesis rate on the assembly of apoB-100-containing lipoproteins in Hep G2 cells. , 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.

[42]  J. Folch,et al.  A simple method for the isolation and purification of total lipides from animal tissues. , 1957, The Journal of biological chemistry.

[43]  Kotb Abdelmohsen,et al.  Posttranslational control of HuR function , 2017, Wiley interdisciplinary reviews. RNA.

[44]  Michael P. Lisanti,et al.  Cancer metabolism: a therapeutic perspective , 2017, Nature Reviews Clinical Oncology.

[45]  Myriam Gorospe,et al.  HuR function in disease. , 2012, Frontiers in bioscience.

[46]  J. Weiss,et al.  Network perspectives of cardiovascular metabolism , 2006 .

[47]  T. Hashimoto,et al.  PEROXISOMAL β-OXIDATION AND PEROXISOME PROLIFERATOR–ACTIVATED RECEPTOR α: An Adaptive Metabolic System , 2001 .

[48]  R. Havel,et al.  Lipoproteins and lipid transport. , 1975, Advances in experimental medicine and biology.

[49]  C. Williamson,et al.  Therapeutic perspective. , 1951, California medicine.