Risk factors in falls among the elderly according to extrinsic and intrinsic precipitating causes

The aim of this prospective cohort study was to identify the risk factors involved in falls in 190 elderly residents of two geriatric centres in Granada (Andalusia, Spain). Because different types of falls may be associated with different factors, falls were classified according to the precipitating cause, either extrinsic or intrinsic. The incidence density and the ratios for crude and adjusted density were calculated. Cox proportional risk analysis was used to calculate adjusted incidence density ratios. Of the 121 falls identified, 63 (52.1%) had a extrinsic precipitating cause, 43 (35.5%) had an intrinsic precipitating cause, and no precipitating cause was determined in 15 falls. The rate of falls with an extrinsic precipitating cause was 0.39 per person per year, while falls with an intrinsic precipitating cause showed a frequency of 0.27 per person per year. For falls with an extrinsic precipitating cause, the most significant risk factors were: age, diabetes mellitus, a history of falling, and treatment with neuroleptics or oral bronchodilators. The number of illnesses acted as a protective factor. For falls with an intrinsic precipitating cause, the independent risk factors were: age, diabetes, dementia, alterations of gait and balance, previous falls, and treatment with digitalins, neuroleptics or antidepressants. These results suggest that the susceptibility to a fall with an intrinsic precipitating cause is easier to identify and has a greater potential for being controlled.

[1]  M. Tinetti,et al.  Drugs and Falls in Older People: A Systematic Review and Meta‐analysis: II. Cardiac and Analgesic Drugs , 1999, Journal of the American Geriatrics Society.

[2]  M. Tinetti Factors Associated with Serious Injury During Falls by Ambulatory Nursing Home Residents , 1987, Journal of the American Geriatrics Society.

[3]  Teresa To,et al.  Use of selective serotonin-reuptake inhibitors or tricyclic antidepressants and risk of hip fractures in elderly people , 1998, The Lancet.

[4]  S. Kivelä,et al.  Incidence rate of falls in an aged population in northern Finland. , 1994, Journal of clinical epidemiology.

[5]  S. Yasumura,et al.  Rate of falls and the correlates among elderly people living in an urban community in Japan. , 1994, Age and ageing.

[6]  D. Kiel,et al.  Identifying Nursing Home Residents at Risk for Falling , 1998, Journal of the American Geriatrics Society.

[7]  K. Kerschan,et al.  Functional impact of unvarying exercise program in women after menopause. , 1998, American journal of physical medicine & rehabilitation.

[8]  S. Studenski,et al.  Effects of Central Nervous System Polypharmacy on Falls Liability in Community-Dwelling Elderly , 1998, Gerontology.

[9]  A. Campbell,et al.  Risk factors for falls in a community-based prospective study of people 70 years and older. , 1989, Journal of gerontology.

[10]  M. Tinetti Performance‐Oriented Assessment of Mobility Problems in Elderly Patients , 1986, Journal of the American Geriatrics Society.

[11]  M. Tinetti,et al.  A multifactorial intervention to reduce the risk of falling among elderly people living in the community. , 1994, The New England journal of medicine.

[12]  L. Lipsitz,et al.  Orthostatic hypotension in the elderly. , 1989, The New England journal of medicine.

[13]  S. Cummings,et al.  Risk factors for recurrent nonsyncopal falls. A prospective study. , 1989, JAMA.

[14]  D. Bauer,et al.  Physical Activity and Osteoporotic Fracture Risk in Older Women , 1998, Annals of Internal Medicine.

[15]  S. Katz,et al.  STUDIES OF ILLNESS IN THE AGED. THE INDEX OF ADL: A STANDARDIZED MEASURE OF BIOLOGICAL AND PSYCHOSOCIAL FUNCTION. , 1963, JAMA.

[16]  D. Prudham,et al.  Factors associated with falls in the elderly: a community study. , 1981, Age and ageing.

[17]  M. Tinetti,et al.  Predictors and prognosis of inability to get up after falls among elderly persons. , 1993, JAMA.

[18]  J. O'Loughlin,et al.  Falls among the elderly: distinguishing indoor and outdoor risk factors in Canada. , 1994, Journal of Epidemiology and Community Health.

[19]  W. Schaffner,et al.  Psychotropic drug use and the risk of hip fracture , 1987 .

[20]  S. Katz,et al.  Progress in development of the index of ADL. , 1970, The Gerontologist.

[21]  A F Hoskin Fatal falls: trends and characteristics. , 1998, Statistical bulletin.

[22]  M. Tinetti,et al.  Fall risk index for elderly patients based on number of chronic disabilities. , 1986, The American journal of medicine.

[23]  B. J. Gales,et al.  Relationship Between the Administration of Selected Medications and Falls in Hospitalized Elderly Patients , 1995, The Annals of pharmacotherapy.

[24]  J. Yesavage,et al.  Geriatric Depression Scale (GDS): Recent evidence and development of a shorter version. , 1986 .

[25]  M. Tinetti,et al.  Drugs and Falls in Older People: A Systematic Review and Meta‐analysis: I. Psychotropic Drugs , 1999, Journal of the American Geriatrics Society.

[26]  J L Kelsey,et al.  Methodologic issues in the study of frequent and recurrent health problems. Falls in the elderly. , 1990, Annals of epidemiology.

[27]  W A Ray,et al.  Antidepressants and the risk of falls among nursing home residents. , 1998, The New England journal of medicine.

[28]  D. Cox Regression Models and Life-Tables , 1972 .

[29]  M. Tinetti,et al.  Identifying mobility dysfunctions in elderly patients. Standard neuromuscular examination or direct assessment? , 1988, JAMA.

[30]  M. Ronthal,et al.  Gait disorders among elderly patients. A survey study of 50 patients. , 1983, Archives of neurology.

[31]  Mark A Pereira,et al.  A randomized walking trial in postmenopausal women: effects on physical activity and health 10 years later. , 1998, Archives of internal medicine.

[32]  S. Furner,et al.  Mortality, disability, and falls in older persons: the role of underlying disease and disability. , 1992, American journal of public health.

[33]  T. Kennedy The prevention of falls in later life. A report of the Kellogg International Work Group on the Prevention of Falls by the Elderly. , 1987, Danish medical bulletin.

[34]  R. Tideiksaar,et al.  What causes falls? A logical diagnostic procedure. , 1986, Geriatrics.

[35]  P. Wingo,et al.  Home Environmental Hazards and the Risk of Fall Injury Events Among Community‐Dwelling Older Persons , 1998, Journal of the American Geriatrics Society.

[36]  M. Zunzunegui,et al.  [The prevalence of and factors associated with falls in older persons living in the community]. , 1997, Medicina clinica.

[37]  J. Yesavage Differential diagnosis between depression and dementia. , 1993, The American journal of medicine.

[38]  M. Tinetti,et al.  Development of the Common Data Base for the FICSIT Trials , 1993, Journal of the American Geriatrics Society.

[39]  T M Gill,et al.  Shared risk factors for falls, incontinence, and functional dependence. Unifying the approach to geriatric syndromes. , 1995, JAMA.

[40]  Christianna S. Williams,et al.  Health care utilization and costs in a Medicare population by fall status. , 1998, Medical care.

[41]  M. V. Van Natta,et al.  Risk factors associated with falls and injuries among elderly institutionalized persons. , 1991, American journal of epidemiology.

[42]  Pekka Laippala,et al.  Risk Factors for Major Injurious Falls among the Home-Dwelling Elderly by Functional Abilities , 1998, Gerontology.

[43]  M. Tinetti,et al.  Risk factors for falls among elderly persons living in the community. , 1988, The New England journal of medicine.

[44]  W. Dixon,et al.  BMDP statistical software , 1983 .

[45]  L. Lipsitz,et al.  Causes and correlates of recurrent falls in ambulatory frail elderly. , 1991, Journal of gerontology.

[46]  J. Crowther,et al.  A simple screening test for hearing impairment in elderly patients. , 1988, Age and ageing.

[47]  J L Kelsey,et al.  Risk factors for falls as a cause of hip fracture in women. The Northeast Hip Fracture Study Group. , 1991, The New England journal of medicine.

[48]  L. Rubenstein,et al.  Falls in the Nursing Home , 1994, Annals of Internal Medicine.

[49]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[50]  S. Baker,et al.  Medications and Diagnoses in Relation to Falls in a Long‐Term Care Facility , 1987, Journal of the American Geriatrics Society.

[51]  J. Cauley,et al.  Physical activity and osteoporotic fracture risk in older women. Study of Osteoporotic Fractures Research Group. , 1998, Annals of internal medicine.

[52]  S. Lord,et al.  Physiological factors associated with injurious falls in older people living in the community. , 1992, Gerontology.

[53]  Hoskin Af Fatal falls: trends and characteristics. , 1998 .

[54]  G. Sorock,et al.  Benzodiazepine sedatives and the risk of falling in a community-dwelling elderly cohort. , 1988, Archives of internal medicine.

[55]  W. Kruse,et al.  FALLS IN COMMUNITY‐DWELLING OLDER PERSONS , 1996, Journal of the American Geriatrics Society.

[56]  J P Miller,et al.  Falls in the Elderly: Reliability of a Classification System , 1991, Journal of the American Geriatrics Society.

[57]  Recurrent elderly fallers. , 1992, Scandinavian journal of primary health care.