A GSM mobile system to monitor brain function using a near-infrared light sensor

This paper presents a versatile mobile system to monitor oxygenated hemoglobin (HBO) and deoxygenated hemoglobin (HB) concentration changes in brain and tissues. The system uses global system for mobile communications (GSM) and Bluetooth networks to provide extended mobility. The system consists of three parts: a wireless near-infrared light sensor with Bluetooth support, a personal digital assistant (PDA) and a personal computer (PC). The sensor connects to the PDA using Bluetooth and the PDA connects to the PC in the lab using GSM and the Internet. The system packages the acquired data using multiple data communication protocols. It is a light-weight solution to monitor brain and tissues in real-life situations. The extended mobility was achieved by building software components in the PDA and the PC to provide the bridge between the Bluetooth sensor and the PC over GSM networks. The system was tested on humans and animals.

[1]  Tuuli Mattelmäki,et al.  Mobile probes , 2004, NordiCHI '04.

[2]  R. Davidson,et al.  Affective neuroscience: the emergence of a discipline , 1995, Current Opinion in Neurobiology.

[3]  Xiaofeng Zhang,et al.  Methodology development for simultaneous diffuse optical tomography and magnetic resonance imaging in functional human brain mapping , 2005, SPIE BiOS.

[4]  Vlad Toronov,et al.  The roles of changes in deoxyhemoglobin concentration and regional cerebral blood volume in the fMRI BOLD signal , 2003, NeuroImage.

[5]  A. Rosen,et al.  A portable near infrared spectroscopy system for bedside monitoring of newborn brain , 2005, Biomedical engineering online.

[6]  Rajiv Chakravorty,et al.  GPRSWeb: optimizing the web for GPRS links , 2003, MobiSys '03.

[7]  R. Cabeza,et al.  Imaging Cognition II: An Empirical Review of 275 PET and fMRI Studies , 2000, Journal of Cognitive Neuroscience.

[8]  F. Jöbsis Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. , 1977, Science.

[9]  Andrzej Duda,et al.  Efficient mobile access to the WWW over GSM , 1998, EW 8.

[10]  E. Gratton,et al.  Fast cerebral functional signal in the 100-ms range detected in the visual cortex by frequency-domain near-infrared spectrophotometry. , 2003, Psychophysiology.

[11]  Upkar Varshney,et al.  Pervasive Healthcare and Wireless Health Monitoring , 2007, Mob. Networks Appl..

[12]  Srinivasan Keshav,et al.  Why cell phones will dominate the future internet , 2005, CCRV.

[13]  B. Chance,et al.  Cognition-activated low-frequency modulation of light absorption in human brain. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[14]  A novel near-infrared spectroscopy (NIRS) system for measuring regional oxygen saturation , 1995, Proceedings of the IEEE 21st Annual Northeast Bioengineering Conference.

[15]  Jennifer Bray,et al.  Bluetooth: Connect Without Cables , 2000 .

[16]  Elmar J. Sinz,et al.  Web-Application-Server , 2000, Wirtschaftsinf..