Melittin enhances radiosensitivity of hypoxic head and neck squamous cell carcinoma by suppressing HIF-1α

[1]  Hong-yan Cheng,et al.  Ginsenoside Rg3 enhances radiosensitization of hypoxic oesophageal cancer cell lines through vascular endothelial growth factor and hypoxia inducible factor 1α , 2014, The Journal of international medical research.

[2]  G. Semenza,et al.  Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology. , 2014, Annual review of pathology.

[3]  Hong-yan Cheng,et al.  Berberine radiosensitizes human nasopharyngeal carcinoma by suppressing hypoxia-inducible factor-1α expression , 2014, Acta oto-laryngologica.

[4]  Saied Mirshahidi,et al.  Combination antiangiogenic therapy and radiation in head and neck cancers. , 2014, Oral oncology.

[5]  Hong-yan Cheng,et al.  HIF-1α P582S and A588T polymorphisms and digestive system cancer risk—a meta-analysis , 2014, Tumor Biology.

[6]  Hong-yan Cheng,et al.  HIF-1α 1772 C/T and 1790 G/A Polymorphisms Are Significantly Associated with Higher Cancer Risk: An Updated Meta-Analysis from 34 Case-Control Studies , 2013, PloS one.

[7]  Hong-yan Cheng,et al.  Berberine enhances radiosensitivity of esophageal squamous cancer by targeting HIF-1α in vitro and in vivo , 2013, Cancer biology & therapy.

[8]  G. Gajski,et al.  Melittin: a lytic peptide with anticancer properties. , 2013, Environmental toxicology and pharmacology.

[9]  E. Schuuring,et al.  Prognostic significance of HIF‐1a, CA‐IX, and OPN in T1–T2 laryngeal carcinoma treated with radiotherapy , 2013, The Laryngoscope.

[10]  Yung-Hyun Choi,et al.  Melittin Suppresses HIF-1α/VEGF Expression through Inhibition of ERK and mTOR/p70S6K Pathway in Human Cervical Carcinoma Cells , 2013, PloS one.

[11]  A. Grosu,et al.  Hypoxia in Head and Neck Tumors: Characteristics and Development during Therapy , 2013, Front. Oncol..

[12]  Paul J. Zhang,et al.  Hypoxia-Inducible Factors: Mediators of Cancer Progression; Prognostic and Therapeutic Targets in Soft Tissue Sarcomas , 2013, Cancers.

[13]  Jie Xu,et al.  Aurora‐A activation, correlated with hypoxia‐inducible factor‐1α, promotes radiochemoresistance and predicts poor outcome for nasopharyngeal carcinoma , 2012, Cancer science.

[14]  Chuan-miao Xie,et al.  Prognostic significance of the various classifications for parapharyngeal space involvement in nasopharyngeal carcinoma , 2011, Acta oto-laryngologica.

[15]  J. Hong,et al.  Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway. , 2012, Toxicology and applied pharmacology.

[16]  A. Walch,et al.  Establishment and Molecular Cytogenetic Characterization of a Cell Culture Model of Head and Neck Squamous Cell Carcinoma (HNSCC) , 2010, Genes.

[17]  Young-Chae Chang,et al.  Melittin suppresses PMA-induced tumor cell invasion by inhibiting NF-κB and AP-1-dependent MMP-9 expression , 2010, Molecules and cells.

[18]  Chaosu Hu,et al.  Hypoxia inducible factor-1 alpha and vascular endothelial growth factor expression are associated with a poor prognosis in patients with nasopharyngeal carcinoma receiving radiotherapy with carbogen and nicotinamide. , 2008, Clinical oncology (Royal College of Radiologists (Great Britain)).

[19]  Yi-quan Ke,et al.  [Melittin inhibits proliferation and induces apoptosis of malignant human glioma cells]. , 2007, Nan fang yi ke da xue xue bao = Journal of Southern Medical University.

[20]  A. Chattopadhyay,et al.  Melittin: a Membrane-active Peptide with Diverse Functions , 2007, Bioscience reports.

[21]  C. Ling,et al.  Growth Arrest and Apoptosis of the Human Hepatocellular Carcinoma Cell Line Bel-7402 Induced by Melittin , 2006, Oncology Research and Treatment.

[22]  X. Zhang,et al.  Effect of polypeptides in bee venom on growth inhibition and apoptosis induction of the human hepatoma cell line SMMC‐7721 in‐vitro and Balb/c nude mice in‐vivo , 2006, The Journal of pharmacy and pharmacology.