Stem and Progenitor Cells of the Airway Epithelium

[1]  N. Kaminski,et al.  Clara cells attenuate the inflammatory response through regulation of macrophage behavior. , 2010, American journal of respiratory cell and molecular biology.

[2]  A. Malkinson,et al.  Clara cell: progenitor for the bronchiolar epithelium. , 2010, The international journal of biochemistry & cell biology.

[3]  Scott H. Randell,et al.  Basal cells as stem cells of the mouse trachea and human airway epithelium , 2009, Proceedings of the National Academy of Sciences.

[4]  F. Watt,et al.  Stem cells are dispensable for lung homeostasis but restore airways after injury , 2009, Proceedings of the National Academy of Sciences.

[5]  Fan Wang,et al.  The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. , 2009, Cell stem cell.

[6]  R. Schwartz,et al.  Multiple roles for Sox2 in the developing and adult mouse trachea , 2009, Development.

[7]  B. Stripp,et al.  Prospective Isolation of Bronchiolar Stem Cells Based Upon Immunophenotypic and Autofluorescence Characteristics , 2009, Stem cells.

[8]  J. McQualter,et al.  Endogenous Fibroblastic Progenitor Cells in the Adult Mouse Lung Are Highly Enriched in the Sca‐1 Positive Cell Fraction , 2009, Stem cells.

[9]  N. Kaminski,et al.  Molecular staging of epithelial maturation using secretory cell-specific genes as markers. , 2009, American journal of respiratory cell and molecular biology.

[10]  B. Driscoll,et al.  Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice. , 2009, American journal of physiology. Lung cellular and molecular physiology.

[11]  B. Hogan,et al.  Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development , 2008, Proceedings of the National Academy of Sciences.

[12]  T. Mariani,et al.  Conditional Stabilization of β‐Catenin Expands the Pool of Lung Stem Cells , 2008, Stem cells.

[13]  B. Stripp,et al.  Maintenance and Repair of the Bronchiolar Epithelium , 2022 .

[14]  B. Hogan,et al.  Epithelial stem/progenitor cells in lung postnatal growth, maintenance, and repair. , 2008, Cold Spring Harbor symposia on quantitative biology.

[15]  David E. Irwin,et al.  Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification. , 2007, American journal of physiology. Lung cellular and molecular physiology.

[16]  B. Stripp,et al.  CCSP regulates cross talk between secretory cells and both ciliated cells and macrophages of the conducting airway. , 2007, American journal of physiology. Lung cellular and molecular physiology.

[17]  M. Goodheart,et al.  Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis. , 2007, Developmental biology.

[18]  T. Betsuyaku,et al.  Molecular and functional properties of lung SP cells. , 2007, American journal of physiology. Lung cellular and molecular physiology.

[19]  R. Hajj,et al.  Basal Cells of the Human Adult Airway Surface Epithelium Retain Transit‐Amplifying Cell Properties , 2007, Stem cells.

[20]  J. Klingensmith,et al.  Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps. , 2006, Differentiation; research in biological diversity.

[21]  S. Hirst.  Encyclopedia of Respiratory Medicine , 2006 .

[22]  J. Whitsett,et al.  Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli. , 2005, American journal of respiratory cell and molecular biology.

[23]  T. Jacks,et al.  Identification of Bronchioalveolar Stem Cells in Normal Lung and Lung Cancer , 2005, Cell.

[24]  C. Dani,et al.  Embryonic stem cells generate airway epithelial tissue. , 2005, American journal of respiratory cell and molecular biology.

[25]  B. Stripp,et al.  Mucin is produced by clara cells in the proximal airways of antigen-challenged mice. , 2004, American journal of respiratory cell and molecular biology.

[26]  K. Pinkerton,et al.  Proximal airway mucous cells of ovalbumin-sensitized and -challenged Brown Norway rats accumulate the neuropeptide calcitonin gene-related peptide. , 2004, American journal of physiology. Lung cellular and molecular physiology.

[27]  Simon C Watkins,et al.  In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations. , 2004, American journal of physiology. Lung cellular and molecular physiology.

[28]  B. Stripp,et al.  Molecular phenotype of airway side population cells. , 2004, American journal of physiology. Lung cellular and molecular physiology.

[29]  D. Warburton,et al.  Isolation of a putative progenitor subpopulation of alveolar epithelial type 2 cells. , 2004, American journal of physiology. Lung cellular and molecular physiology.

[30]  S. Randell,et al.  A subset of mouse tracheal epithelial basal cells generates large colonies in vitro. , 2004, American journal of physiology. Lung cellular and molecular physiology.

[31]  Simon C Watkins,et al.  Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. , 2004, The American journal of pathology.

[32]  K. Wada,et al.  Bombesin-like peptide receptor gene expression, regulation, and function in fetal murine lung. , 2004, American journal of physiology. Lung cellular and molecular physiology.

[33]  D. Kotton,et al.  Side population cells and Bcrp1 expression in lung. , 2003, American journal of physiology. Lung cellular and molecular physiology.

[34]  R. Wu,et al.  Molecular Cloning and Characterization of spurt, a Human Novel Gene That Is Retinoic Acid-inducible and Encodes a Secretory Protein Specific in Upper Respiratory Tracts* , 2003, The Journal of Biological Chemistry.

[35]  B. Stripp,et al.  Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways. , 2002, American journal of respiratory and critical care medicine.

[36]  S. Brody,et al.  Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population. , 2002, American journal of physiology. Lung cellular and molecular physiology.

[37]  D. Sheppard,et al.  Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma , 2002, Nature Medicine.

[38]  Susan E. Wert,et al.  Early restriction of peripheral and proximal cell lineages during formation of the lung , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[39]  B. Stripp,et al.  Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. , 2002, The American journal of pathology.

[40]  C. Plopper,et al.  CELLULAR AND MOLECULAR CHARACTERISTICS OF BASAL CELLS IN AIRWAY EPITHELIUM , 2001, Experimental lung research.

[41]  J. Engelhardt.  Stem cell niches in the mouse airway. , 2001, American journal of respiratory cell and molecular biology.

[42]  B. Stripp,et al.  Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion. , 2001, American journal of respiratory cell and molecular biology.

[43]  S. Morrison,et al.  Stem cell potential: Can anything make anything? , 2001, Current Biology.

[44]  S. Randell,et al.  Evidence for stem-cell niches in the tracheal epithelium. , 2001, American journal of respiratory cell and molecular biology.

[45]  W. Cardoso,et al.  Molecular regulation of lung development. , 2001, Annual review of physiology.

[46]  B. Stripp,et al.  Pulmonary Phenotype of CCSP/UG Deficient Mice: A Consequence of CCSP Deficiency or Altered Clara Cell Function? , 2000, Annals of the New York Academy of Sciences.

[47]  D. Warburton,et al.  Telomerase in alveolar epithelial development and repair. , 2000, American journal of physiology. Lung cellular and molecular physiology.

[48]  Robert Bals,et al.  Epithelial antimicrobial peptides in host defense against infection , 2000, Respiratory research.

[49]  R. Kageyama,et al.  Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. , 2000, Development.

[50]  B. Stripp,et al.  Conditional clara cell ablation reveals a self-renewing progenitor function of pulmonary neuroendocrine cells. , 2000, American journal of physiology. Lung cellular and molecular physiology.

[51]  B. Stripp,et al.  Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration. , 2000, The American journal of pathology.

[52]  B. Stripp,et al.  Alteration of pulmonary neuroendocrine cells during epithelial repair of naphthalene-induced airway injury. , 2000, The American journal of pathology.

[53]  E. Mongodin,et al.  Differentiated and functional human airway epithelium regeneration in tracheal xenografts. , 2000, American journal of physiology. Lung cellular and molecular physiology.

[54]  R. Grosschedl,et al.  Submucosal gland development in the airway is controlled by lymphoid enhancer binding factor 1 (LEF1). , 1999, Development.

[55]  C. Plopper,et al.  Early events in naphthalene-induced acute Clara cell toxicity: comparison of membrane permeability and ultrastructure. , 1999, American journal of respiratory cell and molecular biology.

[56]  J. Dorin,et al.  Murine submucosal glands are clonally derived and show a cystic fibrosis gene-dependent distribution pattern. , 1999, American journal of respiratory cell and molecular biology.

[57]  J. Engelhardt,et al.  Lef1 transcription factor expression defines airway progenitor cell targets for in utero gene therapy of submucosal gland in cystic fibrosis. , 1998, American journal of respiratory cell and molecular biology.

[58]  U. Paulus,et al.  A dynamic model of proliferation and differentiation in the intestinal crypt based on a hypothetical intraepithelial growth factor , 1998, Cell proliferation.

[59]  B. Stripp,et al.  Cell proliferation contributes to PNEC hyperplasia after acute airway injury. , 1997, The American journal of physiology.

[60]  C. Baecher-Allan,et al.  Bleomycin induces strain-dependent alterations in the pattern of epithelial cell-specific marker expression in mouse lung. , 1997, Toxicology and applied pharmacology.

[61]  M. Stahlman,et al.  Ontogeny of Clara cell-specific protein and its mRNA: their association with neuroepithelial bodies in human fetal lung and in bronchopulmonary dysplasia. , 1996, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[62]  B. Stripp,et al.  Plasticity of airway cell proliferation and gene expression after acute naphthalene injury. , 1995, The American journal of physiology.

[63]  J. K. Bubien.  Whole cell sodium conductance of principal cells freshly isolated from rat cortical collecting duct. , 1995, The American journal of physiology.

[64]  J. Yankaskas,et al.  Progenitor cells of the adult human airway involved in submucosal gland development. , 1995, Development.

[65]  C. Plopper,et al.  Relationship of cytochrome P450 activity to Clara cell cytotoxicity. IV. Metabolism of naphthalene and naphthalene oxide in microdissected airways from mice, rats, and hamsters. , 1995, Molecular pharmacology.

[66]  A. Malkinson,et al.  Biology of the Clara cell. , 1994, The American journal of physiology.

[67]  K. Pinkerton,et al.  Differentiated bronchiolar epithelium in alveolar ducts of rats exposed to ozone for 20 months. , 1993, The American journal of pathology.

[68]  D. Hyde,et al.  The role of the nonciliated bronchiolar epithelial (Clara) cell as the progenitor cell during bronchiolar epithelial differentiation in the perinatal rabbit lung. , 1992, American journal of respiratory cell and molecular biology.

[69]  J. Wilson,et al.  Reconstitution of tracheal grafts with a genetically modified epithelium. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[70]  S. Randell,et al.  Properties of rat tracheal epithelial cells separated based on expression of cell surface alpha-galactosyl end groups. , 1991, American journal of respiratory cell and molecular biology.

[71]  R. Hoyt,et al.  Neuroepithelial bodies stimulate proliferation of airway epithelium in fetal hamster lung. , 1991, The American journal of physiology.

[72]  L. Palmer,et al.  Stimulation by cGMP of apical Na channels and cation channels in toad urinary bladder. , 1991, The American journal of physiology.

[73]  T. Sun,et al.  Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis , 1990, Cell.

[74]  T. Sun,et al.  Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells , 1989, Cell.

[75]  N. Dekker,et al.  Role of nonciliated cells in renewal of the bronchial epithelium of rats exposed to NO2. , 1986, The American journal of pathology.

[76]  C. Plopper.  Comparative morphologic features of bronchiolar epithelial cells. The Clara cell. , 1983, The American review of respiratory disease.

[77]  Widdicombe Jg,et al.  The Clara cell. , 1982, European journal of respiratory diseases.

[78]  N. Dekker,et al.  Quantitation of damage to the alveolar epithelium by means of type 2 cell proliferation. , 1978, The American review of respiratory disease.

[79]  M. J. Evans,et al.  Role of the Clara cell in renewal of the bronchiolar epithelium. , 1978, Laboratory investigation; a journal of technical methods and pathology.

[80]  R. J. Stephens,et al.  Renewal of the terminal bronchiolar epithelium in the rat following exposure to NO2 or O3. , 1976, Laboratory investigation; a journal of technical methods and pathology.