Comparative effectiveness of medical interventions in adults versus children.

[1]  C. Camargo,et al.  Inhaled steroids for acute asthma following emergency department discharge. , 2012, The Cochrane database of systematic reviews.

[2]  G. Schwarzer,et al.  Erythropoietin or darbepoetin for patients with cancer. , 2012, The Cochrane database of systematic reviews.

[3]  A. Sheikh,et al.  Antibiotics versus placebo for acute bacterial conjunctivitis. , 2012, The Cochrane database of systematic reviews.

[4]  S. Gibbs,et al.  Topical treatments for cutaneous warts. , 2012, The Cochrane database of systematic reviews.

[5]  T. Jefferson,et al.  Vaccines for preventing influenza in healthy children. , 2012, The Cochrane database of systematic reviews.

[6]  F. Ducharme,et al.  Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. , 2012, The Cochrane database of systematic reviews.

[7]  R. Griffiths,et al.  Water for wound cleansing. , 2012, The Cochrane database of systematic reviews.

[8]  L. Leibovici,et al.  Antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemotherapy. , 2012, The Cochrane database of systematic reviews.

[9]  A. Verhagen,et al.  Interventions for impetigo. , 2012, The Cochrane database of systematic reviews.

[10]  J. Critchley,et al.  Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). , 2011, The Cochrane database of systematic reviews.

[11]  J. Hom,et al.  Beta2-agonists for acute bronchitis. , 2011, The Cochrane database of systematic reviews.

[12]  Stefan Meyer,et al.  Interventions for treating oral mucositis for patients with cancer receiving treatment. , 2010, The Cochrane database of systematic reviews.

[13]  Asbjørn Hróbjartsson,et al.  Placebo interventions for all clinical conditions. , 2010, The Cochrane database of systematic reviews.

[14]  John P A Ioannidis,et al.  Adverse events in randomized trials: neglected, restricted, distorted, and silenced. , 2009, Archives of internal medicine.

[15]  H. Caron,et al.  Different dosage schedules for reducing cardiotoxicity in cancer patients receiving anthracycline chemotherapy. , 2009, The Cochrane database of systematic reviews.

[16]  A. Randolph,et al.  Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. , 2009, The Cochrane database of systematic reviews.

[17]  M. Schonlau,et al.  Off-label prescribing to children in the United States outpatient setting. , 2009, Academic pediatrics.

[18]  Chunbo Li,et al.  Clozapine versus typical neuroleptic medication for schizophrenia. , 2009, The Cochrane database of systematic reviews.

[19]  K. Verhamme,et al.  Drug use in children: cohort study in three European countries , 2008, BMJ : British Medical Journal.

[20]  J. Bruss,et al.  The economics of pediatric formulation development for off-patent drugs. , 2008, Clinical therapeutics.

[21]  C. Pandolfini,et al.  European paediatric research and children's therapeutic needs. A trial review , 2008, Acta paediatrica.

[22]  R. Califf,et al.  Safety Monitoring of Drugs Receiving Pediatric Marketing Exclusivity , 2008, Pediatrics.

[23]  L. Hartling,et al.  Children Are Not Just Small Adults: The Urgent Need for High-Quality Trial Evidence in Children , 2008, PLoS medicine.

[24]  H. Bauchner,et al.  Child Versus Adult Research: The Gap in High-Quality Study Design , 2008, Pediatrics.

[25]  T. Ten Have,et al.  Corticosteroids and mortality in children with bacterial meningitis. , 2008, JAMA.

[26]  V. Hasselblad,et al.  Pediatric Antihypertensive Trial Failures: Analysis of End Points and Dose Range , 2008, Hypertension.

[27]  Shiew-Mei Huang,et al.  Improving Pediatric Dosing Through Pediatric Initiatives: What We Have Learned , 2008, Pediatrics.

[28]  G. Sinha.  EU law mandates drug testing in children. , 2008, Journal of the National Cancer Institute.

[29]  I. Choonara.  Regulation of drugs for children in Europe , 2007, BMJ : British Medical Journal.

[30]  Nikolaos A Patsopoulos,et al.  Uncertainty in heterogeneity estimates in meta-analyses , 2007, BMJ : British Medical Journal.

[31]  R. Holubkov,et al.  Carvedilol for children and adolescents with heart failure: a randomized controlled trial. , 2007, JAMA.

[32]  R. Griffiths,et al.  Water for wound cleansing. , 2007, International journal of evidence-based healthcare.

[33]  B. Rowe,et al.  Corticosteroids for preventing relapse following acute exacerbations of asthma. , 2007, The Cochrane database of systematic reviews.

[34]  Eric L Eisenstein,et al.  Economic return of clinical trials performed under the pediatric exclusivity program. , 2007, JAMA.

[35]  E. Cohen,et al.  An absence of pediatric randomized controlled trials in general medical journals, 1985-2004. , 2007, Journal of clinical epidemiology.

[36]  P. Hunter,et al.  Prevention and treatment of cryptosporidiosis in immunocompromised patients. , 2007, The Cochrane database of systematic reviews.

[37]  M. Aref-Adib,et al.  Risperidone for autism spectrum disorder. , 2007, The Cochrane database of systematic reviews.

[38]  Jing Zhang,et al.  Chinese medicinal herbs for the common cold. , 2007, The Cochrane database of systematic reviews.

[39]  A. Omari,et al.  Primaquine for preventing relapses in people with Plasmodium vivax malaria. , 2007, The Cochrane database of systematic reviews.

[40]  J. Walters,et al.  Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid. , 2007, The Cochrane database of systematic reviews.

[41]  R. Nelson,et al.  Non surgical therapy for anal fissure. , 2012, The Cochrane database of systematic reviews.

[42]  T. Young,et al.  Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children. , 2010, The Cochrane database of systematic reviews.

[43]  J. Wit,et al.  Stimulation programs for pediatric drug research – do children really benefit? , 2007, European Journal of Pediatrics.

[44]  P. Graves,et al.  Vaccines for preventing malaria (pre-erythrocytic). , 2006, The Cochrane database of systematic reviews.

[45]  R. Malthaner,et al.  Cyclosporin versus tacrolimus for liver transplanted patients. , 2006, The Cochrane database of systematic reviews.

[46]  Robert M Califf,et al.  Peer-reviewed publication of clinical trials completed for pediatric exclusivity. , 2006, JAMA.

[47]  C. Sampaio,et al.  Antibiotic prophylaxis for surgical introduction of intracranial ventricular shunts. , 2006, The Cochrane database of systematic reviews.

[48]  B. Strom,et al.  How the US drug safety system should be changed. , 2006, JAMA.

[49]  R. Keren,et al.  Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma. , 2006, The Cochrane database of systematic reviews.

[50]  G. Swingler,et al.  Cotrimoxazole prophylaxis for opportunistic infections in children with HIV infection. , 2006, The Cochrane database of systematic reviews.

[51]  L. Leibovici,et al.  Antibiotics for preventing meningococcal infections. , 2013, The Cochrane database of systematic reviews.

[52]  M. Ní Chróinín,et al.  Long-acting beta2-agonists versus placebo in addition to inhaled corticosteroids in children and adults with chronic asthma. , 2005, The Cochrane database of systematic reviews.

[53]  M. Ní Chróinín,et al.  Combination of inhaled long-acting beta2-agonists and inhaled steroids versus higher dose of inhaled steroids in children and adults with persistent asthma. , 2005, The Cochrane database of systematic reviews.

[54]  C. Gamble,et al.  Topical antibiotics without steroids for chronically discharging ears with underlying eardrum perforations. , 2005, The Cochrane database of systematic reviews.

[55]  C. Gamble,et al.  Artemether-lumefantrine (six-dose regimen) for treating uncomplicated falciparum malaria. , 2005, The Cochrane database of systematic reviews.

[56]  S. Owusu‐Ofori,et al.  Atovaquone-proguanil for treating uncomplicated malaria. , 2005, The Cochrane database of systematic reviews.

[57]  G. Swingler,et al.  Children in reviews: Methodological issues in child-relevant evidence syntheses , 2005, BMC pediatrics.

[58]  C. Gluud,et al.  Sequential combination of glucocorticosteroids and alfa interferon versus alfa interferon alone for HBeAg-positive chronic hepatitis B. , 2005, The Cochrane database of systematic reviews.

[59]  F. Kallehave,et al.  Antibiotics versus placebo for prevention of postoperative infection after appendicectomy. , 2005, The Cochrane database of systematic reviews.

[60]  Harri Hemilä,et al.  Vitamin C for Preventing and Treating the Common Cold , 2005, PLoS medicine.

[61]  Maurizio Bonati,et al.  A literature review on off-label drug use in children , 2005, European Journal of Pediatrics.

[62]  L. Ranganathan,et al.  Vitamins for epilepsy. , 2005, The Cochrane database of systematic reviews.

[63]  C. Gamble,et al.  Topical quinolone vs. antiseptic for treating chronic suppurative otitis media: a randomized controlled trial , 2005, Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery.

[64]  P. Alderson,et al.  Corticosteroids for acute traumatic brain injury. , 2005, The Cochrane database of systematic reviews.

[65]  D. Mabey,et al.  Antibiotics for trachoma. , 2002, The Cochrane database of systematic reviews.

[66]  M. Laopaiboon,et al.  Azithromycin for acute lower respiratory tract infections. , 2015, The Cochrane database of systematic reviews.

[67]  S. Walker,et al.  Anti-IgE for chronic asthma in adults and children. , 2006, The Cochrane database of systematic reviews.

[68]  Drummond Rennie,et al.  Postmarketing surveillance--lack of vigilance, lack of trust. , 2004, JAMA.

[69]  J. Ioannidis,et al.  Better Reporting of Harms in Randomized Trials: An Extension of the CONSORT Statement , 2004, Annals of Internal Medicine.

[70]  P. Rebulla,et al.  Prophylactic platelet transfusion for haemorrhage after chemotherapy and stem cell transplantation. , 2004, The Cochrane database of systematic reviews.

[71]  M. Lucero,et al.  Pneumococcal conjugate vaccines for preventing vaccine-type invasive pneumococcal disease and pneumonia with consolidation on x-ray in children under two years of age. , 2004, The Cochrane database of systematic reviews.

[72]  J. Volmink,et al.  Reduced osmolarity oral rehydration solution for treating cholera. , 2004, The Cochrane database of systematic reviews.

[73]  J. Critchley,et al.  Chlorproguanil-dapsone for treating uncomplicated malaria. , 2004, The Cochrane database of systematic reviews.

[74]  John P A Ioannidis,et al.  Availability of large-scale evidence on specific harms from systematic reviews of randomized trials. , 2004, The American journal of medicine.

[75]  Phyllis N Butow,et al.  Clinical trials in children , 2004, The Lancet.

[76]  R. Tasker,et al.  Hypertonic versus near isotonic crystalloid for fluid resuscitation in critically ill patients. , 2004, The Cochrane database of systematic reviews.

[77]  D. Annane,et al.  Corticosteroids for treating severe sepsis and septic shock. , 2004, The Cochrane database of systematic reviews.

[78]  S. Allen,et al.  Probiotics for treating infectious diarrhoea. , 2003, The Cochrane database of systematic reviews.

[79]  Susan M Abdel-Rahman,et al.  Developmental pharmacology--drug disposition, action, and therapy in infants and children. , 2003, The New England journal of medicine.

[80]  D. Murphy,et al.  Pediatric drug labeling: improving the safety and efficacy of pediatric therapies. , 2003, JAMA.

[81]  P. Budetti.  Ensuring safe and effective medications for children. , 2003, JAMA.

[82]  G. Swingler,et al.  Cotrimoxazole prophylaxis for opportunistic infections in adults with HIV. , 2003, The Cochrane database of systematic reviews.

[83]  Catrin Tudur Smith,et al.  Carbamazepine versus phenobarbitone monotherapy for epilepsy. , 2003, The Cochrane database of systematic reviews.

[84]  G. Goodwin,et al.  Valproate for acute mood episodes in bipolar disorder. , 2003, The Cochrane database of systematic reviews.

[85]  M. Mäkelä,et al.  Antibiotic Therapy for Acute Sinusitis: A Systematic Literature Review , 2003 .

[86]  P. Morris,et al.  WITHDRAWN: Antibiotics for persistent nasal discharge (rhinosinusitis) in children. , 2008, The Cochrane database of systematic reviews.

[87]  M. Meremikwu,et al.  High first dose quinine regimen for treating severe malaria. , 2004, The Cochrane database of systematic reviews.

[88]  T. Hudson,et al.  A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis. , 2002, American journal of human genetics.

[89]  M. Felisi,et al.  Medicines for children licensed by the European Agency for the Evaluation of Medicinal Products , 2002, European Journal of Clinical Pharmacology.

[90]  J. Walters,et al.  Regular treatment with long acting beta agonists versus daily regular treatment with short acting beta agonists in adults and children with stable asthma. , 2002, The Cochrane database of systematic reviews.

[91]  B. Mayosi,et al.  Penicillin for secondary prevention of rheumatic fever. , 2002, The Cochrane database of systematic reviews.

[92]  G. Malenga,et al.  Dexamethasone treatment in childhood bacterial meningitis in Malawi: a randomised controlled trial , 2002, The Lancet.

[93]  Douglas G Altman,et al.  Statistical methods for assessing the influence of study characteristics on treatment effects in ‘meta‐epidemiological’ research , 2002, Statistics in medicine.

[94]  S. Thompson,et al.  Quantifying heterogeneity in a meta‐analysis , 2002, Statistics in medicine.

[95]  A. Marson,et al.  Routine anticonvulsants for treating cerebral malaria. , 2002, The Cochrane database of systematic reviews.

[96]  J L Hutton,et al.  Topiramate for drug-resistant partial epilepsy. , 2000, The Cochrane database of systematic reviews.

[97]  A. Marson,et al.  Lamotrigine add-on for drug-resistant partial epilepsy. , 2016, The Cochrane database of systematic reviews.

[98]  P. Glasziou,et al.  Antibiotics for sore throat. , 2013, Nursing times.

[99]  C. Camargo,et al.  Early use of inhaled corticosteroids in the emergency department treatment of acute asthma. , 2012, The Cochrane database of systematic reviews.

[100]  P. Alderson,et al.  Colloid solutions for fluid resuscitation. , 2012, The Cochrane database of systematic reviews.

[101]  M. Patel,et al.  Polysaccharide vaccines for preventing serogroup A meningococcal meningitis. , 2005, The Cochrane database of systematic reviews.

[102]  F. Ducharme.  Addition of anti-leukotriene agents to inhaled corticosteroids for chronic asthma. , 2004, The Cochrane database of systematic reviews.

[103]  A G Marson,et al.  Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures. , 2001, The Cochrane database of systematic reviews.

[104]  P Middleton,et al.  Quality of Cochrane reviews: assessment of sample from 1998 , 2001, BMJ : British Medical Journal.

[105]  H. Saconato,et al.  Antibiotic prophylaxis for mammalian bites. , 2001, The Cochrane database of systematic reviews.

[106]  J. Ioannidis,et al.  Completeness of safety reporting in randomized trials: an evaluation of 7 medical areas. , 2001, JAMA.

[107]  C. Camargo,et al.  Intravenous beta2-agonists for acute asthma in the emergency department. , 2001, The Cochrane database of systematic reviews.

[108]  L. Dans,et al.  Intravenous immunoglobulin for treating sepsis and septic shock. , 2002, The Cochrane database of systematic reviews.

[109]  D. Schmidt,et al.  Oxcarbazepine add-on for drug-resistant partial epilepsy. , 2016, The Cochrane database of systematic reviews.

[110]  I. Roberts,et al.  Barbiturates for acute traumatic brain injury. , 2012, The Cochrane database of systematic reviews.

[111]  M. Mäkelä,et al.  Antibiotics for acute maxillary sinusitis. , 2008, The Cochrane database of systematic reviews.

[112]  R. Puy,et al.  Allergen immunotherapy for asthma. , 2003, The Cochrane database of systematic reviews.

[113]  T. Jefferson,et al.  Vaccines for preventing cholera. , 2001, The Cochrane database of systematic reviews.

[114]  B. Rowe,et al.  Early emergency department treatment of acute asthma with systemic corticosteroids. , 2001, The Cochrane database of systematic reviews.

[115]  A. Marson,et al.  Carbamazepine versus valproate monotherapy for epilepsy. , 2000, The Cochrane database of systematic reviews.

[116]  G. de Bruyn,et al.  Antibiotic treatment for travellers' diarrhoea. , 2000, The Cochrane database of systematic reviews.

[117]  C. Camargo,et al.  Magnesium sulfate for treating exacerbations of acute asthma in the emergency department. , 2000, The Cochrane database of systematic reviews.

[118]  Maurizio Bonati,et al.  Survey of unlicensed and off label drug use in paediatric wards in European countries , 2000, BMJ : British Medical Journal.

[119]  P. Olliaro,et al.  Artemisinin derivatives for treating uncomplicated malaria. , 1999, The Cochrane database of systematic reviews.

[120]  P. Garner,et al.  Antibiotics for treating salmonella gut infections. , 1999, The Cochrane database of systematic reviews.

[121]  P. Olliaro,et al.  Artemisinin derivatives for treating severe malaria. , 1998, The Cochrane database of systematic reviews.

[122]  I. Roberts,et al.  Human albumin solution for resuscitation and volume expansion in critically ill patients. The Albumin Reviewers. , 2000, The Cochrane database of systematic reviews.

[123]  J. Bestall,et al.  Budesonide versus placebo for chronic asthma in children and adults , 1999 .

[124]  M. Egger,et al.  The hazards of scoring the quality of clinical trials for meta-analysis. , 1999, JAMA.

[125]  J. Kuttesch,et al.  Outpatient treatment of fever and neutropenia for low risk pediatric cancer patients , 1999, Cancer.

[126]  J. Ioannidis,et al.  Can quality of clinical trials and meta-analyses be quantified? , 1998, The Lancet.

[127]  J. Ioannidis,et al.  Quantitative Synthesis in Systematic Reviews , 1997, Annals of Internal Medicine.

[128]  N. Laird,et al.  Meta-analysis in clinical trials. , 1986, Controlled clinical trials.