Protein Phosphatase 2A Inhibiting β-Catenin Phosphorylation Contributes Critically to the Anti-renal Interstitial Fibrotic Effect of Norcantharidin
暂无分享,去创建一个
Ying Li | Chengyuan Tang | Lu Wen | D-K Zeng | Dan-dan Yin | Xun Zhou | Zheng‐Jun Xiao
[1] J. Egido,et al. Interleukin-17A blockade reduces albuminuria and kidney injury in an accelerated model of diabetic nephropathy. , 2019, Kidney international.
[2] Xinzhong Huang,et al. Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β‐catenin activity , 2019, Journal of cellular and molecular medicine.
[3] D. Barber,et al. β-Catenin is a pH sensor with decreased stability at higher intracellular pH , 2018, The Journal of cell biology.
[4] C. Mitchell,et al. &bgr;-catenin ablation exacerbates polycystic kidney disease progression , 2018, Human molecular genetics.
[5] Ming Wang,et al. Novel inhibitors of the cellular renin‐angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β‐catenin pathway against renal fibrosis , 2018, British journal of pharmacology.
[6] A. A. Abdel Moneim,et al. Ziziphus spina-christi (L.) leaf extract alleviates myocardial and renal dysfunction associated with sepsis in mice. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[7] Christopher S. Williams,et al. Protein Phosphatase 2A in the Regulation of Wnt Signaling, Stem Cells, and Cancer , 2018, Genes.
[8] Oscar Cerda,et al. TRPM4 regulates Akt/GSK3‐β activity and enhances β‐catenin signaling and cell proliferation in prostate cancer cells , 2017, Molecular oncology.
[9] Junwei Yang,et al. FHL2 promotes tubular epithelial‐to‐mesenchymal transition through modulating β‐catenin signalling , 2017, Journal of cellular and molecular medicine.
[10] Ashutosh Kumar Singh,et al. Discovery of a Novel Small-Molecule Inhibitor that Targets PP2A–β-Catenin Signaling and Restricts Tumor Growth and Metastasis , 2017, Molecular Cancer Therapeutics.
[11] A. Webster,et al. Chronic Kidney Disease , 2017, The Lancet.
[12] Yasser S. El-Sayed,et al. Nephroprotective efficacy of ceftriaxone against cisplatin-induced subchronic renal fibrosis in rats , 2017, Naunyn-Schmiedeberg's Archives of Pharmacology.
[13] Abdelazim Ibrahim,et al. Nephroprotective effect of bee honey and royal jelly against subchronic cisplatin toxicity in rats , 2016, Cytotechnology.
[14] Yingfeng Wan,et al. Norcantharidin blocks Wnt/β-catenin signaling via promoter demethylation of WIF-1 in glioma. , 2016, Oncology reports.
[15] M. Abdel-Daim,et al. Antagonistic effects of Spirulina platensis against sub-acute deltamethrin toxicity in mice: Biochemical and histopathological studies. , 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[16] Lin Sun,et al. Norcantharidin inhibits renal interstitial fibrosis by downregulating PP2Ac expression. , 2015, American journal of translational research.
[17] A. Zentella,et al. Protein phosphatase 2A is essential to maintain active Wnt signaling and its Aβ tumor suppressor subunit is not expressed in colon cancer cells , 2015, Molecular carcinogenesis.
[18] Yaping Zhang,et al. Norcantharidin inhibits Wnt signal pathway via promoter demethylation of WIF-1 in human non-small cell lung cancer , 2015, Medical Oncology.
[19] M. Abdel-Daim,et al. Synergistic protective effects of ceftriaxone and ascorbic acid against subacute deltamethrin-induced nephrotoxicity in rats , 2015, Renal failure.
[20] Yibing Yan,et al. HSP105 Recruits Protein Phosphatase 2A To Dephosphorylate β-Catenin , 2015, Molecular and Cellular Biology.
[21] L. Yao,et al. High Phosphorus Level Leads to Aortic Calcification via β-Catenin in Chronic Kidney Disease , 2015, American Journal of Nephrology.
[22] Youhua Liu,et al. Wnt/β-catenin signaling and kidney fibrosis , 2014, Kidney international supplements.
[23] A. Shimono,et al. Secreted Frizzled-related Protein 1 (Sfrp1) Regulates the Progression of Renal Fibrosis in a Mouse Model of Obstructive Nephropathy* , 2014, The Journal of Biological Chemistry.
[24] M. Karsdal,et al. The extracellular matrix in the kidney: a source of novel non-invasive biomarkers of kidney fibrosis? , 2014, Fibrogenesis & tissue repair.
[25] Xuehao Wang,et al. Cantharidin Exerts Anti-Hepatocellular Carcinoma by Mir-214 Modulating Macrophage Polarization , 2014, International journal of biological sciences.
[26] U. Schumacher,et al. Pharmacogenomics of cantharidin in tumor cells. , 2014, Biochemical pharmacology.
[27] C. Bao,et al. Aberrant Activation of the WNT/β-Catenin Signaling Pathway in Lupus Nephritis , 2014, PloS one.
[28] Zhi-Hong Liu. Nephrology in China , 2013, Nature Reviews Nephrology.
[29] Y. Li,et al. Norcantharidin Inhibits Renal Interstitial Fibrosis by Blocking the Tubular Epithelial-Mesenchymal Transition , 2013, PloS one.
[30] Jian Dong,et al. Exploiting protein phosphatase inhibitors based on cantharidin analogues for cancer drug discovery. , 2013, Mini reviews in medicinal chemistry.
[31] Jianfeng Cai,et al. Norcantharidin inhibits tumor angiogenesis via blocking VEGFR2/MEK/ERK signaling pathways , 2013, Cancer science.
[32] L. Pannell,et al. DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin , 2012, Oncogene.
[33] L. Deng,et al. A Review for Mini-Review in Medicinal Chemistry. , 2012, Mini-Reviews in Medical Chemistry.
[34] Josef Coresh,et al. Chronic kidney disease , 2012, The Lancet.
[35] G. Ling,et al. Norcantharidin inhibits the expression of extracellular matrix and TGF-β1 in HK-2 cells induced by high glucose independent of calcineurin signal pathway , 2011, Laboratory Investigation.
[36] Youhua Liu. Cellular and molecular mechanisms of renal fibrosis , 2011, Nature Reviews Nephrology.
[37] M. Kahn,et al. Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis. , 2011, Journal of the American Society of Nephrology : JASN.
[38] G. Ling,et al. Norcantharidin Attenuates Tubulointerstitial Fibrosis in Rat Models with Diabetic Nephropathy , 2011, Renal failure.
[39] J. López-Novoa,et al. An integrative view on the role of TGF-beta in the progressive tubular deletion associated with chronic kidney disease. , 2010, Kidney international.
[40] Y. Li,et al. Norcantharidin Ameliorates Proteinuria, Associated Tubulointerstitial Inflammation and Fibrosis in Protein Overload Nephropathy , 2008, American Journal of Nephrology.
[41] J. Misset,et al. Effects of norcantharidin, a protein phosphatase type-2A inhibitor, on the growth of normal and malignant haemopoietic cells. , 1995, European journal of cancer.
[42] M. Li,et al. ILK participates in renal interstitial fibrosis by altering the phenotype of renal tubular epithelial cells via TGF-β1/smad pathway. , 2019, European review for medical and pharmacological sciences.
[43] G. Narla,et al. Therapeutic targeting of PP2A. , 2018, The international journal of biochemistry & cell biology.
[44] Yongping Wang,et al. Wnt Signaling in Kidney Development and Disease. , 2018, Progress in molecular biology and translational science.
[45] C. Xing,et al. The wnt/β-catenin signaling pathway participates in rhein ameliorating kidney injury in DN mice , 2015, Molecular and Cellular Biochemistry.
[46] E. Neilson,et al. Mechanisms of tubulointerstitial fibrosis. , 1991, Kidney international.