A pure nongestational choriocarcinoma of the ovary

Choriocarcinoma arises in the ovary from gestational or nongestational origin. Nongestational choriocarcinoma of the ovary is extremely rare and the pure type is less frequent than the mixed type with other germ cell tumors. We report a pure nongestational choriocarcinoma primarily arising in a 47-year-old woman's ovary. Following abdominal operative procedure, careful examination of the tumor revealed choriocarcinoma without combination of other germ cell tumors. Multiple courses of the chemotherapy with and EMA/CO regimen were effective for this case. horiocarcinoma of the ovary is a rare and aggressive neoplasm. Most ovarian choriocarcinomas are gestational in ori- gin and usually metastasize to the ovary from uterine or tubal choriocarcinomas. Nongesta- tional choriocarcinoma of the ovary is exceed- ingly rare and usually seen with other germ cell tumors. This fact will be a diagnostic aid for its nongestational origin. Furthermore, pure type nongestational choriocarcinoma is extremely rare and its diagnosis is very diffi- cult. We report here a case of pure nongeta- tional choriocarcinoma of the ovary occurring in a 47-year-old woman 4 years after her menopause.