Microwave tomographic spectroscopy for an assessment tissue oxygenation

Microwave tomography, being a novel imaging modality, has potentials for an assessment of functional and pathological conditions of biological tissues. The examples are: tissue malignancies, with recent major focus on breast cancer detection, tissue blood content, ischemia, infarction, stroke and others. Early in non-imaging experiments we have demonstrated the feasibility of the technology for an assessment of tissue oxygenation status. The goal of this preliminary study was to use microwave tomographic spectroscopy for an assessment of tissue oxygenation status during an imaging procedure of swine medial foreleg.

[1]  Robert H. Svenson,et al.  Microwave Spectroscopy of Myocardial Ischemia and Infarction. 2. Biophysical Reconstruction , 2004, Annals of Biomedical Engineering.

[2]  K. Foster,et al.  Dielectric Properties of VX-2 Carcinoma Versus Normal Liver Tissue , 1986, IEEE Transactions on Biomedical Engineering.

[3]  Andrey Pavlovsky,et al.  Microwave tomography of extremities: 2. Functional fused imaging of flow reduction and simulated compartment syndrome , 2011, Physics in medicine and biology.

[4]  Stuchly,et al.  Dielectric properties of breast carcinoma and the surrounding tissues , 1988, IEEE Transactions on Biomedical Engineering.

[5]  W. Joines,et al.  The measured electrical properties of normal and malignant human tissues from 50 to 900 MHz. , 1994, Medical physics.

[6]  S. S. Chaudhary,et al.  Dielectric properties of normal & malignant human breast tissues at radiowave & microwave frequencies. , 1984, Indian journal of biochemistry & biophysics.

[7]  Robert H. Svenson,et al.  Dielectrical spectroscopy of canine myocardium during acute ischemia and hypoxia at frequency spectrum from 100 kHz to 6 GHz , 2002, IEEE Transactions on Medical Imaging.

[8]  Robert H. Svenson,et al.  Microwave tomography: a two-dimensional Newton iterative scheme , 1998 .

[9]  T Iritani,et al.  A study of the electrical bio-impedance of tumors. , 1993, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

[10]  Robert H. Svenson,et al.  Microwave Spectroscopy of Myocardial Ischemia and Infarction. 1. Experimental Study , 2004, Annals of Biomedical Engineering.

[11]  Andrey Pavlovsky,et al.  Microwave tomography of extremities: 1. Dedicated 2D system and physiological signatures , 2011, Physics in medicine and biology.