Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31
暂无分享,去创建一个
Kari Stefansson | Evangelos Evangelou | Fernando Rivadeneira | Gudmar Thorleifsson | Albert Hofman | Rob G H H Nelissen | Aslaug Jonasdottir | Gisli Masson | Asgeir Sigurdsson | Margreet Kloppenburg | Marian Beekman | Tim Spector | Unnur Thorsteinsdottir | Ingrid Meulenbelt | Stefan Lohmander | Unnur Styrkarsdottir | A. Hofman | A. Uitterlinden | T. Spector | J. V. van Meurs | A. Sigurdsson | Á. Jónasdóttir | U. Thorsteinsdóttir | A. Kong | K. Stefánsson | F. Rivadeneira | O. Magnusson | G. Másson | I. Jónsdóttir | G. Thorleifsson | H. Helgadottir | M. Thorsteinsdóttir | M. Frigge | M. Beekman | P. Slagboom | S. Bierma-Zeinstra | S. A. Gudjonsson | E. Evangelou | A. Valdes | N. Arden | S. Lohmander | P. Slagboom | H. Jonsson | D. Hart | R. Nelissen | M. Kloppenburg | T. Ingvarsson | I. Meulenbelt | S. Metrustry | J. Meurs | Augustine Kong | Thorvaldur Ingvarsson | Ingileif Jonsdottir | Sarah Metrustry | P Eline Slagboom | Ana M Valdes | Helgi Jonsson | Sigurjon A Gudjonsson | Hafdis T. Helgadottir | Nigel K Arden | Deborah Hart | Joyce van Meurs | Andre Uitterlinden | Olafur T Magnusson | Michael L Frigge | Margret Thorsteinsdottir | S Bierma-Zeinstra | Hafdis T Helgadottir | Nils Bomer | Annelieke M Strijbosch | Finnur F Eiriksson | N. Bomer | S. Bierma-Zeinstra | F. Eiriksson | A. Valdes | A. Strijbosch | U. Styrkársdóttir | A. Uitterlinden | F. Eiríksson | A. Hofman | Annelieke M. Strijbosch | N. Bomer
[1] Daniel F. Gudbjartsson,et al. Parental origin of sequence variants associated with complex diseases , 2009, Nature.
[2] Pall I. Olason,et al. Detection of sharing by descent, long-range phasing and haplotype imputation , 2008, Nature Genetics.
[3] Allen D. Delaney,et al. Conserved Role of Intragenic DNA Methylation in Regulating Alternative Promoters , 2010, Nature.
[4] L. Gudas. Emerging roles for retinoids in regeneration and differentiation in normal and disease states. , 2012, Biochimica et biophysica acta.
[5] Yusuke Nakamura,et al. Common variants in DVWA on chromosome 3p24.3 are associated with susceptibility to knee osteoarthritis , 2008, Nature Genetics.
[6] P. Chambon,et al. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development , 1999, Nature Genetics.
[7] H. Stefánsson,et al. A common inversion under selection in Europeans , 2005, Nature Genetics.
[8] T. Harris,et al. High hand joint mobility is associated with radiological CMC1 osteoarthritis: the AGES-Reykjavik study. , 2007, Osteoarthritis and cartilage.
[9] Bjarni V. Halldórsson,et al. A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22. , 2010, Arthritis and rheumatism.
[10] Bjarni V. Halldórsson,et al. Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22 , 2010, Annals of the rheumatic diseases.
[11] V. Laudet,et al. From carrot to clinic: an overview of the retinoic acid signaling pathway , 2010, Cellular and Molecular Life Sciences.
[12] M. Peters,et al. Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis , 2012, Proceedings of the National Academy of Sciences.
[13] L. Reynard,et al. Allelic expression analysis of the osteoarthritis susceptibility gene COL11A1 in human joint tissues , 2013, BMC Musculoskeletal Disorders.
[14] Michael Boehnke,et al. LocusZoom: regional visualization of genome-wide association scan results , 2010, Bioinform..
[15] P. Slagboom,et al. Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues , 2012, Annals of the rheumatic diseases.
[16] G. Duester,et al. Retinoic Acid Promotes Limb Induction through Effects on Body Axis Extension but Is Unnecessary for Limb Patterning , 2009, Current Biology.
[17] G. Begemann,et al. New sources of retinoic acid synthesis revealed by live imaging of an Aldh1a2‐GFP reporter fusion protein throughout zebrafish development , 2012, Developmental dynamics : an official publication of the American Association of Anatomists.
[18] K Y Liang,et al. Longitudinal data analysis for discrete and continuous outcomes. , 1986, Biometrics.
[19] A. Hofman,et al. A variant in MCF2L is associated with osteoarthritis. , 2011, American journal of human genetics.
[20] Yusuke Nakamura,et al. New Sequence Variants in HLA Class II/III Region Associated with Susceptibility to Knee Osteoarthritis Identified by Genome-Wide Association Study , 2010, PloS one.
[21] G. Verbruggen,et al. Hand radiology characteristics of patients carrying the T303M mutation in the gene for matrilin‐3 , 2006, Scandinavian journal of rheumatology.
[22] B. Bainbridge,et al. Genetics , 1981, Experientia.
[23] J. Gulcher,et al. The inheritance of hip osteoarthritis in Iceland. , 2000, Arthritis and rheumatism.
[24] Andres Metspalu,et al. Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study , 2012, The Lancet.
[25] David T Felson,et al. Prevalence, incidence and progression of hand osteoarthritis in the general population: the Framingham Osteoarthritis Study , 2011, Annals of the rheumatic diseases.
[26] Raymond K. Auerbach,et al. A User's Guide to the Encyclopedia of DNA Elements (ENCODE) , 2011, PLoS biology.
[27] M. Hellio le Graverand,et al. Evidence for familial aggregation of hand, hip, and spine but not knee osteoarthritis in siblings with multiple joint involvement: the GARP study , 2004, Annals of the rheumatic diseases.
[28] Marian Beekman,et al. Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study , 2006, European Journal of Human Genetics.
[29] K. Schwarz. The Chingford Study. , 1981, Public health.
[30] T. Underhill,et al. Retinoids and their receptors in skeletal development , 1998, Microscopy research and technique.
[31] A. Hofman,et al. Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium. , 2010, Osteoarthritis and cartilage.
[32] P. Donnelly,et al. A new multipoint method for genome-wide association studies by imputation of genotypes , 2007, Nature Genetics.
[33] Daniel F. Gudbjartsson,et al. Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits , 2013, Nature.
[34] K. Roeder,et al. Genomic Control for Association Studies , 1999, Biometrics.
[35] A. Hofman,et al. A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip , 2013, Annals of the rheumatic diseases.
[36] Francesca Chiaromonte,et al. Evaluation of regulatory potential and conservation scores for detecting cis-regulatory modules in aligned mammalian genome sequences. , 2005, Genome research.
[37] Francesca Chiaromonte,et al. ESPERR: learning strong and weak signals in genomic sequence alignments to identify functional elements. , 2006, Genome research.
[38] Michael Inouye,et al. A genotype calling algorithm for the Illumina BeadArray platform , 2007, Bioinform..
[39] G. Duester. Retinoic Acid Synthesis and Signaling during Early Organogenesis , 2008, Cell.
[40] B. Koes,et al. Does hand osteoarthritis predict future hip or knee osteoarthritis? , 2005, Arthritis and rheumatism.
[41] K. Nakashima,et al. [The Rotterdam study]. , 2011, Nihon rinsho. Japanese journal of clinical medicine.
[42] K. Stefánsson,et al. The inheritance of hand osteoarthritis in Iceland. , 2003, Arthritis and rheumatism.
[43] Simon C. Potter,et al. Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study , 2010, Annals of the rheumatic diseases.
[44] 田原 康玄,et al. 生活習慣病とgenome-wide association study , 2015 .
[45] V. Gudnason,et al. Hand Osteoarthritis Severity is Associated with Total Knee Joint Replacements Independently of BMI. The Ages-Reykjavik Study , 2011, The open rheumatology journal.
[46] W. Haenszel,et al. Statistical aspects of the analysis of data from retrospective studies of disease. , 1959, Journal of the National Cancer Institute.
[47] S. Robertson,et al. Craniosynostosis and multiple skeletal anomalies in humans and zebrafish result from a defect in the localized degradation of retinoic acid. , 2011, American journal of human genetics.
[48] Monique M. B. Breteler,et al. The Rotterdam Study: 2016 objectives and design update , 2015, European Journal of Epidemiology.
[49] S. Goldring,et al. Osteoarthritis: a disease of the joint as an organ. , 2012, Arthritis and rheumatism.
[50] C. Rochette-Egly,et al. Vitamin A and retinoid signaling: genomic and nongenomic effects , 2013, Journal of Lipid Research.
[51] C. Cooper,et al. Involvement of different risk factors in clinically severe large joint osteoarthritis according to the presence of hand interphalangeal nodes. , 2010, Arthritis and rheumatism.
[52] P. Diggle,et al. Analysis of Longitudinal Data , 2003 .
[53] T. Underhill,et al. Revisiting the role of retinoid signaling in skeletal development. , 2003, Birth defects research. Part C, Embryo today : reviews.
[54] A. Gylfason,et al. Fine-scale recombination rate differences between sexes, populations and individuals , 2010, Nature.
[55] P. Dollé,et al. Retinoic acid signalling during development , 2012, Development.
[56] Mary Goldman,et al. The UCSC Genome Browser database: extensions and updates 2013 , 2012, Nucleic Acids Res..
[57] T. Spector,et al. Risk factors for osteoarthritis: genetics. , 2004, Osteoarthritis and cartilage.
[58] H. Stefánsson,et al. Genetics of gene expression and its effect on disease , 2008, Nature.
[59] T. Spector,et al. Cigarette smoking and risk of osteoarthritis in women in the general population: the Chingford study. , 1993, Annals of the rheumatic diseases.
[60] R. Moskowitz,et al. The Genetics of Generalized Osteoarthritis (GOGO) study: study design and evaluation of osteoarthritis phenotypes. , 2007, Osteoarthritis and cartilage.
[61] R. Nelissen,et al. Socio-Economic Position Has No Effect on Improvement in Health-Related Quality of Life and Patient Satisfaction in Total Hip and Knee Replacement: A Cohort Study , 2013, PloS one.
[62] David Haussler,et al. ENCODE Data in the UCSC Genome Browser: year 5 update , 2012, Nucleic Acids Res..
[63] M. Arfan Ikram,et al. The Rotterdam Study: 2012 objectives and design update , 2011, European journal of epidemiology.
[64] Tim D Spector,et al. The UK Adult Twin Registry (TwinsUK) , 2006, Twin Research and Human Genetics.