The Interaction between N-WASP and the Arp2/3 Complex Links Cdc42-Dependent Signals to Actin Assembly

[1]  M. Mann,et al.  The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches , 1997, Current Biology.

[2]  Laura M. Machesky,et al.  Scar1 and the related Wiskott–Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex , 1998, Current Biology.

[3]  E. Harlow,et al.  Antibodies: A Laboratory Manual , 1988 .

[4]  M. Beckerle Spatial Control of Actin Filament Assembly Lessons from Listeria , 1998, Cell.

[5]  P. Caroni,et al.  Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase , 1998, Nature.

[6]  L. Van Aelst,et al.  Rho GTPases and signaling networks. , 1997, Genes & development.

[7]  D. Drubin,et al.  Origins of Cell Polarity , 1996, Cell.

[8]  T. Takenawa,et al.  Identification of N-WASP homologs in human and rat brain. , 1997, Gene.

[9]  Paul A. Janmey,et al.  Corequirement of Specific Phosphoinositides and Small GTP-binding Protein Cdc42 in Inducing Actin Assembly in Xenopus Egg Extracts , 1998, The Journal of cell biology.

[10]  K. Miura,et al.  N‐WASP, a novel actin‐depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2‐dependent manner downstream of tyrosine kinases. , 1996, The EMBO journal.

[11]  A. Hall,et al.  Rho GTPases and the actin cytoskeleton. , 1998, Science.

[12]  R. Batchelor Antibodies in the laboratory , 1987, Nature.

[13]  T. Mitchison,et al.  Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation. , 1998, Science.

[14]  T. Takenawa,et al.  Direct binding of the verprolin-homology domain in N-WASP to actin is essential for cytoskeletal reorganization. , 1998, Biochemical and biophysical research communications.

[15]  T. Pollard,et al.  Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose , 1994, The Journal of cell biology.

[16]  P. Janmey,et al.  Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets , 1995, Cell.

[17]  Rong Li,et al.  Bee1, a Yeast Protein with Homology to Wiscott-Aldrich Syndrome Protein, Is Critical for the Assembly of Cortical Actin Cytoskeleton , 1997, The Journal of cell biology.

[18]  C. Saxe,et al.  SCAR, a WASP-related Protein, Isolated as a Suppressor of Receptor Defects in Late Dictyostelium Development , 1998, The Journal of cell biology.

[19]  C. Sasakawa,et al.  Neural Wiskott–Aldrich syndrome protein is implicated in the actin‐based motility of Shigella flexneri , 1998, The EMBO journal.

[20]  Anne J. Ridley,et al.  The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors , 1992, Cell.

[21]  Yoshimi Takai,et al.  Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP , 1998, Nature.

[22]  W. Crocker,et al.  Polarity , 1910, Botanical Gazette.

[23]  Anne J. Ridley,et al.  The small GTP-binding protein rac regulates growth factor-induced membrane ruffling , 1992, Cell.

[24]  Timothy J. Mitchison,et al.  Actin polymerization is induced by Arp 2/3 protein complex at the surface of Listeria monocytogenes , 1997, Nature.

[25]  A. Ackermann Wasp stings. , 1979, The Australasian nurses journal.

[26]  L. Zheng,et al.  Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho. , 1996, The Biochemical journal.

[27]  T. Mitchison,et al.  Actin-Based Cell Motility and Cell Locomotion , 1996, Cell.

[28]  E. Nishida,et al.  Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization , 1998, Nature.

[29]  A. Toker,et al.  Signalling through the lipid products of phosphoinositide-3-OH kinase , 1997, Nature.

[30]  S. Zigmond Actin cytoskeleton: The Arp2/3 complex gets to the point , 1998, Current Biology.

[31]  T D Pollard,et al.  The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[32]  U. Francke,et al.  Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization , 1996, Cell.

[33]  A. DePace,et al.  The Human Arp2/3 Complex Is Composed of Evolutionarily Conserved Subunits and Is Localized to Cellular Regions of Dynamic Actin Filament Assembly , 1997, The Journal of cell biology.

[34]  Shiro Suetsugu,et al.  WAVE, a novel WASP‐family protein involved in actin reorganization induced by Rac , 1998, The EMBO journal.

[35]  Douglas I. Johnson Cdc42: An Essential Rho-Type GTPase Controlling Eukaryotic Cell Polarity , 1999, Microbiology and Molecular Biology Reviews.

[36]  S. Zigmond,et al.  Actin polymerization: Where the WASP stings , 1999, Current Biology.

[37]  K. Oegema,et al.  Cytokinesis in eukaryotes: a mechanistic comparison. , 1999, Current opinion in cell biology.

[38]  T D Pollard,et al.  Sequences, structural models, and cellular localization of the actin- related proteins Arp2 and Arp3 from Acanthamoeba , 1995, The Journal of cell biology.

[39]  M. Kirschner,et al.  The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[40]  P. Hawkins,et al.  Activation of the small GTP-binding proteins rho and rac by growth factor receptors. , 1995, Journal of cell science.

[41]  K L Gould,et al.  The Arp2/3 complex: a multifunctional actin organizer. , 1999, Current opinion in cell biology.