Prognostic significance of high‐grade dysplasia in colorectal adenomas

Aim  Colonoscopy to detect and remove polyps has contributed to a reduction in colorectal carcinoma. Three‐year follow up is recommended for patients considered to be at high risk (at least three adenomas, adenoma ≥ 1 cm, villous or high‐grade features). Our study focused on patients diagnosed with high‐grade dysplasia with regard to initial management and follow up.

[1]  David S Alberts,et al.  A pooled analysis of advanced colorectal neoplasia diagnoses after colonoscopic polypectomy. , 2009, Gastroenterology.

[2]  E. G. Hahn,et al.  Risk of advanced metachronous colorectal adenoma during long-term follow-up , 2008, International Journal of Colorectal Disease.

[3]  J. Goldblum,et al.  Should HGD or Degree of Villous Changes in Colon Polyps Be Reported? , 2008, The American Journal of Gastroenterology.

[4]  J. Goldblum,et al.  PRO: Villous Elements and High-Grade Dysplasia Help Guide Post-Polypectomy Colonoscopic Surveillance , 2008, The American Journal of Gastroenterology.

[5]  P. Albert,et al.  Postpolypectomy Colonoscopy Surveillance Guidelines: Predictive Accuracy for Advanced Adenoma at 4 Years , 2008, Annals of Internal Medicine.

[6]  Dawn Provenzale,et al.  Five-year colon surveillance after screening colonoscopy. , 2007, Gastroenterology.

[7]  M. Pellisé,et al.  Displasia de alto grado como factor de riesgo de neoplasia colorrectal avanzada metacrónica, en pacientes con adenomas avanzados , 2007 .

[8]  S. Saini,et al.  Incidence of advanced adenomas at surveillance colonoscopy in patients with a personal history of colon adenomas: a meta-analysis and systematic review. , 2006, Gastrointestinal endoscopy.

[9]  D. Jonkers,et al.  Endoscopic follow-up of 383 patients with colorectal adenoma: an observational study in daily practice , 2006, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.

[10]  Robert H Fletcher,et al.  Guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society. , 2006, CA: a cancer journal for clinicians.

[11]  J. Habbema,et al.  Colorectal cancer risk in adenoma patients: A nation‐wide study , 2004, International journal of cancer.

[12]  C. O'Morain,et al.  Colorectal Adenoma Characteristics as Predictors of Recurrence , 2004, Diseases of the colon and rectum.

[13]  M F Dixon,et al.  The Vienna classification of gastrointestinal epithelial neoplasia , 2000, Gut.

[14]  J. Potter,et al.  Pathologic features of initial adenomas as predictors for metachronous adenomas of the rectum. , 1998, Journal of the National Cancer Institute.

[15]  G. Beck,et al.  Adenoma characteristics at first colonoscopy as predictors of adenoma recurrence and characteristics at follow-up. The Polyp Prevention Study Group. , 1998, Gastroenterology.

[16]  A. Zauber,et al.  Initial management and follow-up surveillance of patients with colorectal adenomas. , 1997, Gastroenterology clinics of North America.

[17]  A. Neugut,et al.  Incidence and recurrence rates of colorectal adenomas: a prospective study. , 1995, Gastroenterology.

[18]  T. Eide.  Risk of colorectal cancer in adenoma‐bearing individuals within a defined population , 1986, International journal of cancer.

[19]  P. Pinsky,et al.  Ongoing colorectal cancer risk despite surveillance colonoscopy: the Polyp Prevention Trial Continued Follow-up Study. , 2010, Gastrointestinal endoscopy.

[20]  E. Berg,et al.  World Health Organization Classification of Tumours , 2002 .

[21]  Stanley R. Hamilton,et al.  Pathology and genetics of tumours of the digestive system , 2000 .

[22]  M. Stolte,et al.  Differences in the diagnostic criteria used by japanese and western pathologists to diagnose colorectal carcinoma , 1998, Cancer.

[23]  D. Wood.  Tumors of the intestines , 1967 .