Human cytomegalovirus immediate-early protein 2 (IE2)-mediated activation of cyclin E is cell-cycle-independent and forces S-phase entry in IE2-arrested cells.
暂无分享,去创建一个
[1] J. Alwine,et al. Human Cytomegalovirus Major Immediate-Early Proteins and Simian Virus 40 Large T Antigen Can Inhibit Apoptosis through Activation of the Phosphatidylinositide 3′-OH Kinase Pathway and the Cellular Kinase Akt , 2002, Journal of Virology.
[2] Yoon-Jae Song,et al. Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: A DNA microarray analysis , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[3] T. Shenk,et al. Construction of a rationally designed human cytomegalovirus variant encoding a temperature-sensitive immediate-early 2 protein , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[4] M. Marschall,et al. Efficient and tightly regulated expression systems for the human cytomegalovirus major transactivator protein IE2p86 in permissive cells. , 2002, Virus research.
[5] S. Reed,et al. Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line , 2001, Nature.
[6] Anders Zetterberg,et al. Accumulation of Cyclin E Is Not a Prerequisite for Passage through the Restriction Point , 2001, Molecular and Cellular Biology.
[7] A. Kurosky,et al. Degradation of p21cip1 in Cells Productively Infected with Human Cytomegalovirus , 2001, Journal of Virology.
[8] C. Hagemeier,et al. The human cytomegalovirus immediate early 2 protein dissociates cellular DNA synthesis from cyclin‐dependent kinase activation , 2001, The EMBO journal.
[9] J. Bartek,et al. Pathways governing G1/S transition and their response to DNA damage , 2001, FEBS letters.
[10] A. Marchini,et al. Human Cytomegalovirus with IE-2 (UL122) Deleted Fails To Express Early Lytic Genes , 2001, Journal of Virology.
[11] T. Kowalik,et al. Role of Human Cytomegalovirus Immediate-Early Proteins in Cell Growth Control , 2000, Journal of Virology.
[12] M. Stinski,et al. The Human Cytomegalovirus IE86 Protein Can Block Cell Cycle Progression after Inducing Transition into the S Phase of Permissive Cells , 2000, Journal of Virology.
[13] R. Caswell,et al. Human cytomegalovirus mediates cell cycle progression through G(1) into early S phase in terminally differentiated cells. , 2000, The Journal of general virology.
[14] T. Rudge,et al. Murine Cytomegalovirus Stimulates Cellular Thymidylate Synthase Gene Expression in Quiescent Cells and Requires the Enzyme for Replication , 2000, Journal of Virology.
[15] D. Spector,et al. Dysregulation of Cyclin E Gene Expression in Human Cytomegalovirus-Infected Cells Requires Viral Early Gene Expression and Is Associated with Changes in the Rb-Related Protein p130 , 2000, Journal of Virology.
[16] E. Fortunato,et al. Exploitation of cellular signaling and regulatory pathways by human cytomegalovirus. , 2000, Trends in microbiology.
[17] C. Hagemeier,et al. Human Cytomegalovirus 86-Kilodalton IE2 Protein Blocks Cell Cycle Progression in G1 , 1999, Journal of Virology.
[18] E. Flemington,et al. Genetic Dissection of Cell Growth Arrest Functions Mediated by the Epstein-Barr Virus Lytic Gene Product, Zta , 1999, Journal of Virology.
[19] S. Reed,et al. Deregulated cyclin E induces chromosome instability , 1999, Nature.
[20] J. Nevins,et al. Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[21] R. Chetty,et al. Cyclin E in human cancers , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[22] T. Krude. Mimosine arrests proliferating human cells before onset of DNA replication in a dose-dependent manner. , 1999, Experimental cell research.
[23] Liang Zhu,et al. Requirement of Cyclin E-Cdk2 Inhibition in p16INK4a-Mediated Growth Suppression , 1998, Molecular and Cellular Biology.
[24] T. Albrecht,et al. The Cyclin E Promoter Is Activated by Human Cytomegalovirus 86-kDa Immediate Early Protein* , 1998, The Journal of Biological Chemistry.
[25] E. Fortunato,et al. Cell Cycle Dysregulation by Human Cytomegalovirus: Influence of the Cell Cycle Phase at the Time of Infection and Effects on Cyclin Transcription , 1998, Journal of Virology.
[26] E. Fortunato,et al. Identification of domains within the human cytomegalovirus major immediate-early 86-kilodalton protein and the retinoblastoma protein required for physical and functional interaction with each other , 1997, Journal of virology.
[27] N. Harel,et al. TAF-like functions of human cytomegalovirus immediate-early proteins , 1997, Journal of virology.
[28] B. Plachter,et al. The UL84 protein of human cytomegalovirus acts as a transdominant inhibitor of immediate-early-mediated transactivation that is able to prevent viral replication , 1997, Journal of virology.
[29] W. Bresnahan,et al. Human cytomegalovirus infection results in altered Cdk2 subcellular localization. , 1997, The Journal of general virology.
[30] S. Reed,et al. Cyclin E-induced S phase without activation of the pRb/E2F pathway. , 1997, Genes & development.
[31] P. Chi,et al. Inhibition of cellular Cdk2 activity blocks human cytomegalovirus replication. , 1997, Virology.
[32] T. Shenk,et al. Human Cytomegalovirus IE1 and IE2 Proteins are Mutagenic and Mediate ``Hit-And-Run" Oncogenic Transformation in Cooperation with the Adenovirus E1A Proteins , 1997 .
[33] D. Dittmer,et al. Human cytomegalovirus infection inhibits G1/S transition , 1997, Journal of virology.
[34] T. Shenk,et al. Human cytomegalovirus infection inhibits cell cycle progression at multiple points, including the transition from G1 to S , 1996, Journal of virology.
[35] T. Albrecht,et al. Human cytomegalovirus inhibits cellular DNA synthesis and arrests productively infected cells in late G1. , 1996, Virology.
[36] P. Cook,et al. Mimosine arrests the cell cycle after cells enter S-phase. , 1996, Experimental cell research.
[37] T. Shenk,et al. Human cytomegalovirus IE1 and IE2 proteins block apoptosis , 1995, Journal of virology.
[38] J. Corbeil,et al. Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest , 1995, Journal of virology.
[39] J. Nevins,et al. Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes , 1995, Molecular and cellular biology.
[40] M. Leon,et al. Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. , 1994, Science.
[41] T. Kouzarides,et al. Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein. , 1994, The EMBO journal.
[42] M. Gossen,et al. Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. , 1994, Molecular and cellular biology.
[43] S. Elledge,et al. Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle. , 1992, Science.
[44] E. Huang,et al. E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection , 1992, Molecular and cellular biology.
[45] S. Reed,et al. Association of human cyclin E with a periodic G1-S phase protein kinase. , 1992, Science.
[46] James M. Roberts,et al. Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle , 1992 .
[47] S. Green,et al. A versatile in vivo and in vitro eukaryotic expression vector for protein engineering , 1988, Nucleic Acids Res..
[48] D. Coen,et al. A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[49] T. Shenk,et al. Manipulation of the cell cycle by human cytomegalovirus. , 2002, Frontiers in bioscience : a journal and virtual library.
[50] A. Mares,et al. HIT AND RUN , 1999 .
[51] W. Kaelin,et al. Fluorescence-activated cell sorting of transfected cells. , 1997, Methods in enzymology.
[52] C. Lehner,et al. The role of cyclin E in the regulation of entry into S phase. , 1995, Progress in cell cycle research.