Withaferin A-stimulated Ca2+ entry, ceramide formation and suicidal death of erythrocytes.
暂无分享,去创建一个
[1] Huanjun Chen,et al. In vitro effect of CTAB- and PEG-coated gold nanorods on the induction of eryptosis/erythroptosis in human erythrocytes , 2012, Nanotoxicology.
[2] F. Lang,et al. Enhanced suicidal erythrocyte death in mice carrying a loss-of-function mutation of the adenomatous polyposis coli gene , 2012, Journal of cellular and molecular medicine.
[3] K. Roby,et al. Inhibition of cell growth and induction of apoptosis in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural withanolide Withaferin A. , 2012, Gynecologic oncology.
[4] S. Kong,et al. Polyphyllin D induces apoptosis in human erythrocytes through Ca2+ rise and membrane permeabilization , 2012, Archives of Toxicology.
[5] O. Borst,et al. Dynamic adhesion of eryptotic erythrocytes to endothelial cells via CXCL16/SR-PSOX. , 2012, American journal of physiology. Cell physiology.
[6] B. Maček,et al. Protein Kinase CK1α Regulates Erythrocyte Survival , 2012, Cellular Physiology and Biochemistry.
[7] C. De Felice,et al. Erythrocyte caspase-3 activation and oxidative imbalance in erythrocytes and in plasma of type 2 diabetic patients , 2013, Acta Diabetologica.
[8] A. Marcus,et al. Withaferin A inhibits breast cancer invasion and metastasis at sub‐cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation , 2011, International journal of cancer.
[9] F. Lang,et al. p38 MAPK Activation and Function following Osmotic Shock of Erythrocytes , 2011, Cellular Physiology and Biochemistry.
[10] E. S. Yang,et al. Combination of withaferin A and X-ray irradiation enhances apoptosis in U937 cells. , 2011, Toxicology in vitro : an international journal published in association with BIBRA.
[11] F. Lang,et al. Dicoumarol Activates Ca2+-permeable Cation Channels Triggering Erythrocyte Cell Membrane Scrambling , 2011, Cellular Physiology and Biochemistry.
[12] G. Gusev,et al. Fluoride-induced death of rat erythrocytes in vitro. , 2011, Toxicology in vitro : an international journal published in association with BIBRA.
[13] Ramesh C. Gupta,et al. Withaferin A induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells. , 2011, Carcinogenesis.
[14] Xuan Zhang,et al. Down-regulation of estrogen receptor-alpha and rearranged during transfection tyrosine kinase is associated with withaferin a-induced apoptosis in MCF-7 breast cancer cells , 2011, BMC complementary and alternative medicine.
[15] B. Van Houten,et al. Withaferin A-Induced Apoptosis in Human Breast Cancer Cells Is Mediated by Reactive Oxygen Species , 2011, PloS one.
[16] F. Lang,et al. Sphingosine but not Sphingosine-1-phosphate Stimulates Suicidal Erythrocyte Death , 2011, Cellular Physiology and Biochemistry.
[17] F. Lang,et al. Stimulation of Suicidal Erythrocyte Death by Benzethonium , 2011, Cellular Physiology and Biochemistry.
[18] Shivendra V. Singh,et al. Withaferin a suppresses estrogen receptor‐α expression in human breast cancer cells , 2011, Molecular carcinogenesis.
[19] B. Debuire,et al. Withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2 , 2011, Apoptosis.
[20] F. Lang,et al. Janus Kinase 3 is Expressed in Erythrocytes, Phosphorylated Upon Energy Depletion and Involved in the Regulation of Suicidal Erythrocyte Death , 2011, Cellular Physiology and Biochemistry.
[21] K. M. Felder,et al. Hemotrophic Mycoplasmas Induce Programmed Cell Death in Red Blood Cells , 2011, Cellular Physiology and Biochemistry.
[22] M. Rodríguez-Moran,et al. Eryptosis and oxidative damage in type 2 diabetic mellitus patients with chronic kidney disease , 2011, Molecular and Cellular Biochemistry.
[23] E. Park,et al. Endoplasmic reticulum stress mediates withaferin A-induced apoptosis in human renal carcinoma cells. , 2011, Toxicology in vitro : an international journal published in association with BIBRA.
[24] T. Kwon,et al. Withaferin A enhances radiation-induced apoptosis in Caki cells through induction of reactive oxygen species, Bcl-2 downregulation and Akt inhibition. , 2011, Chemico-biological interactions.
[25] M. Schaller,et al. The NFĸB Pathway Inhibitors Bay 11-7082 and Parthenolide Induce Programmed Cell Death in Anucleated Erythrocytes , 2011, Cellular Physiology and Biochemistry.
[26] F. Lang,et al. Stimulation of Suicidal Erythrocyte Death by α-Lipoic Acid , 2011, Cellular Physiology and Biochemistry.
[27] V. Bisaria,et al. Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera’s key metabolite withaferin A , 2010, BMC Genomics.
[28] V. Bisaria,et al. Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes , 2010, BMC Genomics.
[29] Shivendra V. Singh,et al. Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells. , 2010, Carcinogenesis.
[30] E. Schuchman,et al. Acid Sphingomyelinase Deficiency Attenuates Bleomycin-Induced Lung Inflammation and Fibrosis in Mice , 2010, Cellular Physiology and Biochemistry.
[31] F. Lang,et al. FTY720-Induced Suicidal Erythrocyte Death , 2010, Cellular Physiology and Biochemistry.
[32] B. Timmermann,et al. Withaferin A, a cytotoxic steroid from Vassobia breviflora, induces apoptosis in human head and neck squamous cell carcinoma. , 2010, Journal of natural products.
[33] F. Lang,et al. Effect of Amphotericin B on Parasitemia and Survival of Plasmodium Berghei-infected Mice , 2010, Cellular Physiology and Biochemistry.
[34] M. Quintanar-Escorza,et al. Oxidative damage increases intracellular free calcium [Ca2+]i concentration in human erythrocytes incubated with lead. , 2010, Toxicology in vitro : an international journal published in association with BIBRA.
[35] F. Lang,et al. Effect of Anandamide in Plasmodium Berghei-infected Mice , 2010, Cellular Physiology and Biochemistry.
[36] Yang Zhang,et al. Ceramide in Redox Signaling and Cardiovascular Diseases , 2010, Cellular Physiology and Biochemistry.
[37] Yang Zhang,et al. Ceramide in Pseudomonas aeruginosa Infections and Cystic Fibrosis , 2010, Cellular Physiology and Biochemistry.
[38] W. Kuebler,et al. Vascular Barrier Regulation by PAF, Ceramide, Caveolae, and NO - an Intricate Signaling Network with Discrepant Effects in the Pulmonary and Systemic Vasculature , 2010, Cellular Physiology and Biochemistry.
[39] K. Fassbender,et al. Spingolipids in Multiple Sclerosis , 2010, Cellular Physiology and Biochemistry.
[40] J. Kornhuber,et al. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): A Novel Pharmacological Group of Drugs with Broad Clinical Applications , 2010, Cellular Physiology and Biochemistry.
[41] F. Lang,et al. Ceramide in Suicidal Death of Erythrocytes , 2010, Cellular Physiology and Biochemistry.
[42] Tao Zhang,et al. Withaferin A targets heat shock protein 90 in pancreatic cancer cells. , 2010, Biochemical pharmacology.
[43] C. Damodaran,et al. Notch-1 Inhibition by Withaferin-A: A Therapeutic Target against Colon Carcinogenesis , 2010, Molecular Cancer Therapeutics.
[44] S. M. de la Monte,et al. Insulin resistance and Alzheimer's disease. , 2009, BMB reports.
[45] H. J. Um,et al. Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. , 2009, Free radical biology & medicine.
[46] E. Schleicher,et al. Regulation of erythrocyte survival by AMP‐activated protein kinase , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[47] M. Mirjalili,et al. Genetic and Withaferin A Analysis of Iranian Natural Populations of Withania Somnifera and W. Coagulans by RAPD and HPTLC , 2009, Natural product communications.
[48] Xiongwei Zhu,et al. Insulin is a two-edged knife on the brain. , 2009, Journal of Alzheimer's disease : JAD.
[49] O. Pappo,et al. Beta-glycosphingolipids improve glucose intolerance and hepatic steatosis of the Cohen diabetic rat. , 2009, American journal of physiology. Endocrinology and metabolism.
[50] R. Maitra,et al. Inhibition of NFκB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation , 2009, Journal of Inflammation.
[51] D. Zappulla. Environmental stress, erythrocyte dysfunctions, inflammation, and the metabolic syndrome: adaptations to CO2 increases? , 2008, Journal of the cardiometabolic syndrome.
[52] H. Lerche,et al. Eryptosis, a Window to Systemic Disease , 2008, Cellular Physiology and Biochemistry.
[53] Yung-Hyun Choi,et al. Induction of apoptosis by withaferin A in human leukemia U937 cells through down-regulation of Akt phosphorylation , 2008, Apoptosis.
[54] R. Sangwan,et al. Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade , 2008, Apoptosis.
[55] Shivendra V. Singh,et al. Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo. , 2008, Cancer research.
[56] F. Hofmann,et al. Anemia and splenomegaly in cGKI-deficient mice , 2008, Proceedings of the National Academy of Sciences.
[57] Jeong-Yeh Yang,et al. Withaferin A induces apoptosis and inhibits adipogenesis in 3T3‐L1 adipocytes , 2008, BioFactors.
[58] S. Summers,et al. Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism. , 2008, Endocrine reviews.
[59] F. Lang,et al. TRPC6 Contributes to the Ca2+ Leak of Human Erythrocytes , 2008, Cellular Physiology and Biochemistry.
[60] S. Bhushan,et al. Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine , 2007, Apoptosis.
[61] Chang-Guo Zhan,et al. The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin. , 2007, Chemistry & biology.
[62] A. Verkhratsky,et al. Insulin‐like growth factor‐1‐dependent maintenance of neuronal metabolism through the phosphatidylinositol 3‐kinase–Akt pathway is inhibited by C2‐ceramide in CAD cells , 2007, The European journal of neuroscience.
[63] Seng H. Cheng,et al. Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes , 2007, Diabetes.
[64] S. Pramanik,et al. Apoptosis is induced in leishmanial cells by a novel protein kinase inhibitor withaferin A and is facilitated by apoptotic topoisomerase I–DNA complex , 2007, Cell Death and Differentiation.
[65] Guoqing Shi,et al. The Tumor Proteasome Is a Primary Target for the Natural Anticancer Compound Withaferin A Isolated from “Indian Winter Cherry” , 2007, Molecular Pharmacology.
[66] H. Hefter,et al. Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide , 2007, Nature Medicine.
[67] J. Chung,et al. Lysophosphatidic Acid Induces Thrombogenic Activity Through Phosphatidylserine Exposure and Procoagulant Microvesicle Generation in Human Erythrocytes , 2006, Arteriosclerosis, thrombosis, and vascular biology.
[68] D. Chendil,et al. Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells. , 2007, Cancer research.
[69] F. Lang,et al. Monensin Induced Suicidal Erythrocyte Death , 2006, Cellular Physiology and Biochemistry.
[70] P. Comfurius,et al. Surface exposure of phosphatidylserine in pathological cells , 2005, Cellular and Molecular Life Sciences CMLS.
[71] Devi Pu. Withania somnifera Dunal (Ashwagandha): potential plant source of a promising drug for cancer chemotherapy and radiosensitization. , 1996 .