A strategy to improve serum-tolerant transfection activity of polycation vectors by surface hydroxylation.

[1]  Baoan Chen,et al.  Biocompatibility of Fe3O4/DNR magnetic nanoparticles in the treatment of hematologic malignancies , 2010, International journal of nanomedicine.

[2]  Xian‐Zheng Zhang,et al.  Galactosyl conjugated N-succinyl-chitosan-graft-polyethylenimine for targeting gene transfer. , 2010, Molecular bioSystems.

[3]  R. Zhuo,et al.  PEGylated PEI-based biodegradable polymers as non-viral gene vectors. , 2010, Acta biomaterialia.

[4]  L. Greenbaum.  From skin cells to hepatocytes: advances in application of iPS cell technology. , 2010, The Journal of clinical investigation.

[5]  R. Kurzrock,et al.  Epidermal growth factor receptor mutation and diverse tumors: Case report and concise literature review , 2010, Molecular oncology.

[6]  D. Brooks,et al.  Adsorption of amphiphilic hyperbranched polyglycerol derivatives onto human red blood cells. , 2010, Biomaterials.

[7]  Y. Nagasaki,et al.  Enhanced cytoplasmic delivery of siRNA using a stabilized polyion complex based on PEGylated nanogels with a cross-linked polyamine structure. , 2009, Biomacromolecules.

[8]  M. Ogris,et al.  An Acid Sensitive Ketal-Based Polyethylene Glycol-Oligoethylenimine Copolymer Mediates Improved Transfection Efficiency at Reduced Toxicity , 2008, Pharmaceutical Research.

[9]  R. Zhuo,et al.  Functionalized thermoresponsive micelles self-assembled from biotin-PEG-b-P(NIPAAm-co-HMAAm)-b-PMMA for tumor cell target. , 2008, Bioconjugate chemistry.

[10]  J. Y. Lee,et al.  Polyethyleneimine-mediated gene delivery into human adipose derived stem cells. , 2008, Biomaterials.

[11]  Suzie H Pun,et al.  Extracellular barriers to in Vivo PEI and PEGylated PEI polyplex-mediated gene delivery to the liver. , 2008, Bioconjugate chemistry.

[12]  Shu Wang,et al.  Self-assembled ternary complexes of plasmid DNA, low molecular weight polyethylenimine and targeting peptide for nonviral gene delivery into neurons. , 2007, Biomaterials.

[13]  D. W. Pack,et al.  Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions. , 2006, Biomacromolecules.

[14]  K. Yoshikawa,et al.  Hyaluronic acid and its derivative as a multi-functional gene expression enhancer: protection from non-specific interactions, adhesion to targeted cells, and transcriptional activation. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[15]  W. Seeger,et al.  Nano-carriers for DNA delivery to the lung based upon a TAT-derived peptide covalently coupled to PEG-PEI. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[16]  M. Shau,et al.  Structural characterization and buffering capacity in relation to the transfection efficiency of biodegradable polyurethane. , 2005, Bioconjugate chemistry.

[17]  J. Kopeček,et al.  PEGylation of poly(ethylene imine) affects stability of complexes with plasmid DNA under in vivo conditions in a dose-dependent manner after intravenous injection into mice. , 2005, Bioconjugate chemistry.

[18]  K. Boheler,et al.  Embryonic stem cells: prospects for developmental biology and cell therapy. , 2005, Physiological reviews.

[19]  Sung Wan Kim,et al.  Polyethylenimine with acid-labile linkages as a biodegradable gene carrier. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[20]  G. Mao,et al.  Influence of TAT-peptide polymerization on properties and transfection activity of TAT/DNA polyplexes. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[21]  C. van Nostrum,et al.  Poly(3-guanidinopropyl methacrylate): a novel cationic polymer for gene delivery. , 2004, Bioconjugate chemistry.

[22]  D. Porteous,et al.  HIV-1 Tat protein transduction domain peptide facilitates gene transfer in combination with cationic liposomes. , 2004, Journal of controlled release : official journal of the Controlled Release Society.

[23]  Tomoko Ito,et al.  Novel receptor-mediated gene delivery system comprising plasmid/protamine/sugar-containing polyanion ternary complex. , 2004, Biomaterials.

[24]  H. von Briesen,et al.  Human serum albumin-polyethylenimine nanoparticles for gene delivery. , 2003, Journal of controlled release : official journal of the Controlled Release Society.

[25]  K. Leong,et al.  Multifunctional nanorods for gene delivery , 2003, Nature materials.

[26]  W. Tseng,et al.  Improved stability of polycationic vector by dextran-grafted branched polyethylenimine. , 2003, Biomacromolecules.

[27]  H. Too,et al.  Polyethylene glycol modified polyethylenimine for improved CNS gene transfer: effects of PEGylation extent. , 2003, Biomaterials.

[28]  Jeong-Sook Park,et al.  Enhancement of polyethylene glycol (PEG)‐modified cationic liposome‐mediated gene deliveries: effects on serum stability and transfection efficiency , 2003, The Journal of pharmacy and pharmacology.

[29]  C Russell Middaugh,et al.  Barriers to nonviral gene delivery. , 2003, Journal of pharmaceutical sciences.

[30]  I. Schmidt-Wolf,et al.  Non-viral and hybrid vectors in human gene therapy: an update. , 2003, Trends in molecular medicine.

[31]  P. Couvreur,et al.  Nanoparticles in cancer therapy and diagnosis. , 2002, Advanced drug delivery reviews.

[32]  D. Fischer,et al.  Synthesis, Characterization, and Biocompatibility of Polyethylenimine-graft-poly(ethylene glycol) Block Copolymers , 2002 .

[33]  Clive J Roberts,et al.  Polyethylenimine-graft-poly(ethylene glycol) copolymers: influence of copolymer block structure on DNA complexation and biological activities as gene delivery system. , 2002, Bioconjugate chemistry.

[34]  D. Fischer,et al.  Poly(ethylenimine-co-L-lactamide-co-succinamide): a biodegradable polyethylenimine derivative with an advantageous pH-dependent hydrolytic degradation for gene delivery. , 2002, Bioconjugate chemistry.

[35]  V. Torchilin,et al.  TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[36]  J. Jog,et al.  Preparation, characterization and in vitro biocompatibility evaluation of poly(butylene terephthalate)/wollastonite composites. , 2001, Biomaterials.

[37]  B. Kinsey,et al.  Aerosol delivery of robust polyethyleneimine-DNA complexes for gene therapy and genetic immunization. , 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

[38]  P. Low,et al.  Optimization of folate-conjugated liposomal vectors for folate receptor-mediated gene therapy. , 1999, Journal of pharmaceutical sciences.

[39]  Andrea Bodnar,et al.  Human Endothelial Cell Life Extension by Telomerase Expression* , 1999, The Journal of Biological Chemistry.

[40]  D. Fischer,et al.  A Novel Non-Viral Vector for DNA Delivery Based on Low Molecular Weight, Branched Polyethylenimine: Effect of Molecular Weight on Transfection Efficiency and Cytotoxicity , 1999, Pharmaceutical Research.

[41]  J. Behr,et al.  Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody‐derivatized polyethylenimines (PEI) , 1999, The journal of gene medicine.

[42]  Simon C Watkins,et al.  Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection , 1999, Gene Therapy.

[43]  M. Ogris,et al.  PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery , 1999, Gene Therapy.

[44]  L. Barrett,et al.  Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery , 1999, Gene Therapy.

[45]  K Mechtler,et al.  The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells , 1998, Gene Therapy.

[46]  T. Friedmann,et al.  Polybrene increases the efficiency of gene transfer by lipofection , 1998, Gene Therapy.

[47]  Leaf Huang,et al.  Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA , 1997, Gene Therapy.

[48]  D. McDonald,et al.  Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice. , 1997, The American journal of physiology.

[49]  K. Mechtler,et al.  Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery. , 1996, Human gene therapy.

[50]  F. Szoka,et al.  Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. , 1996, Biochemistry.

[51]  D. Tidd,et al.  Partial protection of oncogene, anti-sense oligodeoxynucleotides against serum nuclease degradation using terminal methylphosphonate groups. , 1989, British Journal of Cancer.

[52]  C. Dick,et al.  Characterization of Polyethylenimine , 1970 .

[53]  Dexter B. Pattison.  Cyclic Ethers Made by Pyrolysis of Carbonate Esters , 1957 .

[54]  Wenguang Liu,et al.  Enhanced gene transfection and serum stability of polyplexes by PDMAEMA-polysulfobetaine diblock copolymers. , 2011, Biomaterials.

[55]  Won Jong Kim,et al.  Biodegradable nanoparticles modified by branched polyethylenimine for plasmid DNA delivery. , 2010, Biomaterials.

[56]  Y. Tabata,et al.  Dextran–spermine polycation: an efficient nonviral vector for in vitro and in vivo gene transfection , 2004, Gene Therapy.