Progesterone's role in neuroprotection, a review of the evidence
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[1] D. Stein,et al. Post-stroke infections exacerbate ischemic brain injury in middle-aged rats: Immunomodulation and neuroprotection by progesterone , 2013, Neuroscience.
[2] D. Stein,et al. Combination treatment with progesterone and vitamin D hormone is more effective than monotherapy in ischemic stroke: The role of BDNF/TrkB/Erk1/2 signaling in neuroprotection , 2013, Neuropharmacology.
[3] M. Schumacher,et al. Progesterone Attenuates Several Hippocampal Abnormalities of the Wobbler Mouse , 2013, Journal of neuroendocrinology.
[4] Erden Erol Unluer,et al. Neuroprotective effects of progesterone in spinal cord ischemia in rabbits. , 2013, The American journal of emergency medicine.
[5] M. Khaksari,et al. Differences in brain edema and intracranial pressure following traumatic brain injury across the estrous cycle: Involvement of female sex steroid hormones , 2013, Brain Research.
[6] M. Schumacher,et al. Distribution of membrane progesterone receptor alpha in the male mouse and rat brain and its regulation after traumatic brain injury , 2013, Neuroscience.
[7] Chaokun Li,et al. Progesterone treatment before experimental hypoxia-ischemia enhances the expression of glucose transporter proteins GLUT1 and GLUT3 in neonatal rats , 2013, Neuroscience Bulletin.
[8] M. E. Brocca,et al. Progesterone down-regulates spinal cord inflammatory mediators and increases myelination in experimental autoimmune encephalomyelitis , 2012, Neuroscience.
[9] T. Peterson,et al. A comparison of the effects of nicotinamide and progesterone on functional recovery of cognitive behavior following cortical contusion injury in the rat. , 2012, Journal of neurotrauma.
[10] D. Reddy,et al. Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis , 2012, Epilepsy & Behavior.
[11] M. Moradi,et al. Comparison of the administration of progesterone versus progesterone and vitamin D in improvement of outcomes in patients with traumatic brain injury: A randomized clinical trial with placebo group , 2012, Advanced biomedical research.
[12] C. Beyer,et al. Long-term cerebral cortex protection and behavioral stabilization by gonadal steroid hormones after transient focal hypoxia , 2012, The Journal of Steroid Biochemistry and Molecular Biology.
[13] Richard F. Thompson,et al. Allopregnanolone restores hippocampal-dependent learning and memory and neural progenitor survival in aging 3xTgAD and nonTg mice , 2012, Neurobiology of Aging.
[14] J. Poderoso,et al. Progesterone prevents mitochondrial dysfunction in the spinal cord of wobbler mice , 2012, Journal of neurochemistry.
[15] M. Sperling,et al. Progesterone vs placebo therapy for women with epilepsy , 2012, Neurology.
[16] R. Rigolio,et al. Neuroprotective Effects of Progesterone in Chronic Experimental Autoimmune Encephalomyelitis , 2012, Journal of neuroendocrinology.
[17] M. Schumacher,et al. Progesterone receptors: a key for neuroprotection in experimental stroke. , 2012, Endocrinology.
[18] D. Stein,et al. Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway , 2012, Neuroscience.
[19] S. Bigler,et al. Allopregnanolone increases the number of dopaminergic neurons in substantia nigra of a triple transgenic mouse model of Alzheimer's disease. , 2012, Current Alzheimer research.
[20] D. Vohora,et al. Effect of medroxyprogesterone on development of pentylenetetrazole-induced kindling in mice , 2012, Neuroscience.
[21] D. Stein,et al. Progesterone and low-dose vitamin D hormone treatment enhances sparing of memory following traumatic brain injury , 2012, Hormones and Behavior.
[22] T. Ikeda,et al. Progesterone and allopregnanolone exacerbate hypoxic-ischemic brain injury in immature rats , 2012, Experimental Neurology.
[23] Zhuo Yang,et al. Progesterone increases circulating endothelial progenitor cells and induces neural regeneration after traumatic brain injury in aged rats. , 2012, Journal of neurotrauma.
[24] D. Ahn,et al. Progesterone produces antinociceptive and neuroprotective effects in rats with microinjected lysophosphatidic acid in the trigeminal nerve root , 2012, Molecular pain.
[25] J. Huston,et al. Chronic progesterone treatment of male rats with unilateral 6-hydroxydopamine lesion of the dorsal striatum exasperates parkinsonian symptoms , 2011, Neuroscience.
[26] Chao Jiang,et al. Microglia and cyclooxygenase-2: possible therapeutic targets of progesterone for stroke. , 2011, International immunopharmacology.
[27] R. Cabrera,et al. Progesterone prevents depression-like behavior in a model of Parkinson's disease induced by 6-hydroxydopamine in male rats , 2011, Pharmacology Biochemistry and Behavior.
[28] L. Garay,et al. Progesterone attenuates demyelination and microglial reaction in the lysolecithin-injured spinal cord , 2011, Neuroscience.
[29] M. Hoane,et al. The effect of progesterone dose on gene expression after traumatic brain injury. , 2011, Journal of neurotrauma.
[30] M. Schumacher,et al. Progesterone attenuates astro- and microgliosis and enhances oligodendrocyte differentiation following spinal cord injury , 2011, Experimental Neurology.
[31] Chao Jiang,et al. Progesterone influences postischemic synaptogenesis in the CA1 region of the hippocampus in rats , 2011, Synapse.
[32] J. Epp,et al. Progesterone treatment normalizes the levels of cell proliferation and cell death in the dentate gyrus of the hippocampus after traumatic brain injury , 2011, Experimental Neurology.
[33] R. Irwin,et al. Allopregnanolone Promotes Regeneration and Reduces β-Amyloid Burden in a Preclinical Model of Alzheimer's Disease , 2011, PloS one.
[34] P. Roig,et al. Progesterone prevents nerve injury-induced allodynia and spinal NMDA receptor upregulation in rats. , 2011, Pain medicine.
[35] C. Gibson,et al. Progesterone is neuroprotective following cerebral ischaemia in reproductively ageing female mice. , 2011, Brain : a journal of neurology.
[36] D. Stein,et al. Genomic profile of Toll-like receptor pathways in traumatically brain-injured mice: effect of exogenous progesterone , 2011, Journal of Neuroinflammation.
[37] M. Cekic,et al. Vitamin D deficiency reduces the benefits of progesterone treatment after brain injury in aged rats , 2011, Neurobiology of Aging.
[38] C. Beyer,et al. Gonadal steroids prevent cell damage and stimulate behavioral recovery after transient middle cerebral artery occlusion in male and female rats , 2011, Brain, Behavior, and Immunity.
[39] J. Henry,et al. Progesterone prevents development of neuropathic pain in a rat model: Timing and duration of treatment are critical , 2011, Journal of pain research.
[40] Gang Chen,et al. Progesterone Administration Modulates Cortical TLR4/NF-κB Signaling Pathway after Subarachnoid Hemorrhage in Male Rats , 2011, Mediators of inflammation.
[41] Chao Jiang,et al. Progesterone inhibits inflammatory response pathways after permanent middle cerebral artery occlusion in rats. , 2011, Molecular medicine reports.
[42] D. Stein,et al. Sickness behaviors following medial frontal cortical contusions in male rats , 2011, Behavioural Brain Research.
[43] A. Walf,et al. Progesterone, administered before kainic acid, prevents decrements in cognitive performance in the Morris Water Maze , 2011, Developmental neurobiology.
[44] T. Arora,et al. Effect of progesterone on phosphamidon-induced impairment of memory and oxidative stress in rats , 2011, Human & experimental toxicology.
[45] B. Albayrak,et al. The effects of medroxy progesterone acetate on the pro-inflammatory cytokines, TNF-alpha and IL-1beta in the early phase of the spinal cord injury , 2011, Neurological research.
[46] S. Briyal,et al. Disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis , 2010, Neuropharmacology.
[47] C. Gibson,et al. Sustained levels of progesterone prior to the onset of cerebral ischemia are not beneficial to female mice , 2010, Brain Research.
[48] D. Stein,et al. Progesterone and allopregnanolone attenuate blood–brain barrier dysfunction following permanent focal ischemia by regulating the expression of matrix metalloproteinases , 2010, Experimental Neurology.
[49] Dong-liang Li,et al. [Effect of progesterone on MMP-3 expression in neonatal rat brain after hypoxic-ischemia]. , 2010, Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology.
[50] C. Pike,et al. Continuous and cyclic progesterone differentially interact with estradiol in the regulation of Alzheimer-like pathology in female 3xTransgenic-Alzheimer's disease mice. , 2010, Endocrinology.
[51] Guo-dong Liu,et al. Progesterone attenuates neurological behavioral deficits of experimental autoimmune encephalomyelitis through remyelination with nucleus-sublocalized Olig1 protein , 2010, Neuroscience Letters.
[52] M. Sokabe,et al. Treatment with progesterone after focal cerebral ischemia suppresses proliferation of progenitor cells but enhances survival of newborn neurons in adult male mice , 2010, Neuropharmacology.
[53] Chao Jiang,et al. Neuroprotective effects of progesterone following stroke in aged rats , 2010, Behavioural Brain Research.
[54] N. Shahrokhi,et al. Effect of sex steroid hormones on brain edema, intracranial pressure, and neurologic outcomes after traumatic brain injury. , 2010, Canadian journal of physiology and pharmacology.
[55] H. Offner,et al. Progesterone treatment reduces disease severity and increases IL-10 in experimental autoimmune encephalomyelitis , 2010, Journal of Neuroimmunology.
[56] D. Caruso,et al. Dihydroprogesterone Increases the Gene Expression of Myelin Basic Protein in Spinal Cord of Diabetic Rats , 2010, Journal of Molecular Neuroscience.
[57] Richard F. Thompson,et al. Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease , 2010, Proceedings of the National Academy of Sciences.
[58] A. Prakash,et al. Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice , 2010, Pharmacology Biochemistry and Behavior.
[59] S. Kulkarni,et al. Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice. , 2009, Methods and findings in experimental and clinical pharmacology.
[60] C. Bethea,et al. Ovarian Steroids Decrease DNA Fragmentation In Serotonin Neurons of Non-injured Rhesus Macaques , 2009, Molecular Psychiatry.
[61] M. Meyer,et al. Protective effects of progesterone administration on axonal pathology in mice with experimental autoimmune encephalomyelitis , 2009, Brain Research.
[62] M. Schumacher,et al. Effects of progesterone on oligodendrocyte progenitors, oligodendrocyte transcription factors, and myelin proteins following spinal cord injury , 2009, Glia.
[63] Marc Fisher,et al. Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations , 2009, Stroke.
[64] M. Sokabe,et al. Progesterone promotes the survival of newborn neurons in the dentate gyrus of adult male mice , 2009, Hippocampus.
[65] Chao Jiang,et al. Progesterone exerts neuroprotective effects by inhibiting inflammatory response after stroke , 2009, Inflammation Research.
[66] D. Stein,et al. Direct inhibition of the mitochondrial permeability transition pore: A possible mechanism for better neuroprotective effects of allopregnanolone over progesterone , 2009, Brain Research.
[67] A. Walf,et al. Progesterone reduces depression-like behavior in a murine model of Alzheimer’s Disease , 2009, AGE.
[68] G. Cavaletti,et al. Docetaxel‐induced peripheral neuropathy: protective effects of dihydroprogesterone and progesterone in an experimental model , 2009, Journal of the peripheral nervous system : JPNS.
[69] D. Stein,et al. Effects of progesterone administration on infarct volume and functional deficits following permanent focal cerebral ischemia in rats , 2009, Brain Research.
[70] M. Schumacher,et al. Progesterone Effects on Neuronal Ultrastructure and Expression of Microtubule-associated Protein 2 (MAP2) in Rats with Acute Spinal Cord Injury , 2009, Cellular and Molecular Neurobiology.
[71] C. Gibson,et al. Progesterone, BDNF and Neuroprotection in the Injured CNS , 2009, The International journal of neuroscience.
[72] Ü. Tan,et al. Effects of Progesterone on Total Brain Tissue Adenosine Deaminase Activity in Experimental Epilepsy , 2009, The International journal of neuroscience.
[73] Ji-Xin Shi,et al. Progesterone administration modulates TLRs/NF-kappaB signaling pathway in rat brain after cortical contusion. , 2008, Annals of clinical and laboratory science.
[74] J. Crabbe,et al. The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in mice , 2008, Brain Research.
[75] M. Sharifzadeh,et al. Role of nitric oxide in the anticonvulsive effect of progesterone , 2008, Epilepsy & Behavior.
[76] E. Cavalheiro,et al. Effect of hormonal replacement therapy in the hippocampus of ovariectomized epileptic female rats using the pilocarpine experimental model , 2008, Epilepsy Research.
[77] D. Caruso,et al. Neuroprotective Effects of Dihydroprogesterone and Progesterone in an Experimental Model of Nerve Crush Injury , 2022 .
[78] Dong-liang Li,et al. [Effect of progesterone on the expression of GLUT in the brain following hypoxic-ischemia in newborn rats]. , 2008, Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology.
[79] Ying Zhu,et al. Two different molecular mechanisms underlying progesterone neuroprotection against ischemic brain damage , 2008, Neuropharmacology.
[80] M. Cekic,et al. Progesterone and its Metabolite Allopregnanolone Differentially Regulate Hemostatic Proteins after Traumatic Brain Injury , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[81] M. Meyer,et al. Steroid Protection in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis , 2008, Neuroimmunomodulation.
[82] B. Medhi,et al. Neuroprotective effect of progesterone on acute phase changes induced by partial global cerebral ischaemia in mice , 2008, The Journal of pharmacy and pharmacology.
[83] Ji-Xin Shi,et al. Effects of progesterone on intestinal inflammatory response, mucosa structure alterations, and apoptosis following traumatic brain injury in male rats. , 2008, The Journal of surgical research.
[84] S. Scheff,et al. Efficacy of progesterone following a moderate unilateral cortical contusion injury. , 2008, Journal of neurotrauma.
[85] Guoming Xiao,et al. Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: a randomized controlled trial , 2008, Critical care.
[86] J. Crabbe,et al. Decreased anticonvulsant efficacy of allopregnanolone during ethanol withdrawal in female Withdrawal Seizure-Prone vs. Withdrawal Seizure-Resistant mice , 2008, Neuropharmacology.
[87] A. Walf,et al. Effects of progesterone administration and APPswe+PSEN1Δe9 mutation for cognitive performance of mid-aged mice , 2008, Neurobiology of Learning and Memory.
[88] D. Wright,et al. Effects of medroxyprogesterone acetate on cerebral oedema and spatial learning performance after traumatic brain injury in rats , 2008, Brain injury.
[89] U. Tan,et al. THE EFFECT OF PROGESTERONE ON TOTAL BRAIN TISSUE SIALIC ACID LEVELS IN EXPERIMENTAL EPILEPSY , 2008, The International journal of neuroscience.
[90] Frank Z. Stanczyk,et al. Progesterone and Estrogen Regulate Alzheimer-Like Neuropathology in Female 3xTg-AD Mice , 2007, The Journal of Neuroscience.
[91] L. Garay,et al. Effects of progesterone in the spinal cord of a mouse model of multiple sclerosis , 2007, The Journal of Steroid Biochemistry and Molecular Biology.
[92] Wei-guo Liu,et al. Inhibitory effect of progesterone on inflammatory factors after experimental traumatic brain injury. , 2007, Biomedical and environmental sciences : BES.
[93] M. Cekic,et al. Neurosteroids reduce inflammation after TBI through CD55 induction , 2007, Neuroscience Letters.
[94] M. Cekic,et al. Progesterone improves acute recovery after traumatic brain injury in the aged rat. , 2007, Journal of neurotrauma.
[95] C. Hang,et al. Progesterone Prevents Traumatic Brain Injury-Induced Intestinal Nuclear Factor kappa B Activation and Proinflammatory Cytokines Expression in Male Rats , 2007, Mediators of inflammation.
[96] M. Singh. Progestins and neuroprotection: are all progestins created equal? , 2007, Minerva endocrinologica.
[97] R. Vink,et al. Effects of progesterone on neurologic and morphologic outcome following diffuse traumatic brain injury in rats , 2007, Experimental Neurology.
[98] David W Wright,et al. ProTECT: a randomized clinical trial of progesterone for acute traumatic brain injury. , 2007, Annals of emergency medicine.
[99] S. Scheff,et al. Effects of progesterone on experimental spinal cord injury , 2007, Brain Research.
[100] G. Cavaletti,et al. Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: A multimodal analysis , 2007, Neuroscience.
[101] W. Burnham,et al. The anticonvulsant effects of allopregnanolone against amygdala-kindled seizures in female rats , 2007, Neuroscience Letters.
[102] D. Stein,et al. The enantiomer of progesterone acts as a molecular neuroprotectant after traumatic brain injury , 2006, Neuropharmacology.
[103] D. Stein,et al. Tapered progesterone withdrawal promotes long-term recovery following brain trauma , 2006, Experimental Neurology.
[104] C. Frye,et al. Reduced metabolites mediate neuroprotective effects of progesterone in the adult rat hippocampus. The synthetic progestin medroxyprogesterone acetate (Provera) is not neuroprotective. , 2006, Journal of neurobiology.
[105] D. Krause,et al. Estrogen and progestagens differentially modulate vascular proinflammatory factors. , 2006, American journal of physiology. Endocrinology and metabolism.
[106] W. Burnham,et al. The anticonvulsant effects of progesterone and its metabolites on amygdala-kindled seizures in male rats , 2006, Brain Research.
[107] D. Stein,et al. Slow-release and injected progesterone treatments enhance acute recovery after traumatic brain injury , 2006, Pharmacology Biochemistry and Behavior.
[108] D. Stein,et al. Progesterone administration modulates AQP4 expression and edema after traumatic brain injury in male rats , 2006, Experimental Neurology.
[109] D. Stein,et al. Allopregnanolone, a progesterone metabolite, is more effective than progesterone in reducing cortical infarct volume after transient middle cerebral artery occlusion. , 2006, Annals of emergency medicine.
[110] M. Schumacher,et al. Progesterone increases the expression of myelin basic protein and the number of cells showing NG2 immunostaining in the lesioned spinal cord. , 2006, Journal of neurotrauma.
[111] G. Fiskum,et al. Physiologic progesterone reduces mitochondrial dysfunction and hippocampal cell loss after traumatic brain injury in female rats , 2006, Experimental Neurology.
[112] R. Vink,et al. Both estrogen and progesterone attenuate edema formation following diffuse traumatic brain injury in rats , 2005, Brain Research.
[113] D. Stein,et al. Tapered progesterone withdrawal enhances behavioral and molecular recovery after traumatic brain injury , 2005, Experimental Neurology.
[114] M. Schumacher,et al. Progesterone restores retrograde labeling of cervical motoneurons in Wobbler mouse motoneuron disease , 2005, Experimental Neurology.
[115] C. Frye,et al. Estrogen-priming can enhance progesterone's anti-seizure effects in part by increasing hippocampal levels of allopregnanolone , 2005, Pharmacology Biochemistry and Behavior.
[116] G. Moralí,et al. Post-ischemic administration of progesterone in rats exerts neuroprotective effects on the hippocampus , 2005, Neuroscience Letters.
[117] D. Wright,et al. Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury , 2005, Brain Research.
[118] M. Schumacher,et al. The membrane‐associated progesterone‐binding protein 25‐Dx is expressed in brain regions involved in water homeostasis and is up‐regulated after traumatic brain injury , 2005, Journal of neurochemistry.
[119] G. Ling,et al. Progesterone differentially regulates pro- and anti-apoptotic gene expression in cerebral cortex following traumatic brain injury in rats. , 2005, Journal of neurotrauma.
[120] D. Constantin,et al. Progesterone suppresses the inflammatory response and nitric oxide synthase-2 expression following cerebral ischemia , 2005, Experimental Neurology.
[121] C. Gibson,et al. Modulatory effects of progesterone on inducible nitric oxide synthase expression in vivo and in vitro , 2005, Journal of neurochemistry.
[122] C. Frye,et al. Actions at GABAA receptors in the hippocampus may mediate some antiseizure effects of progestins , 2005, Epilepsy & Behavior.
[123] P. Morris,et al. The neuroprotective effect of progesterone after traumatic brain injury in male mice is independent of both the inflammatory response and growth factor expression , 2005, The European journal of neuroscience.
[124] C. Frye,et al. Attenuating 5α-pregnane-3α-ol-20-one formation in the hippocampus of female rats increases pentylenetetrazole-induced seizures , 2005, Epilepsy & Behavior.
[125] M. Schumacher,et al. Progesterone neuroprotection in spinal cord trauma involves up-regulation of brain-derived neurotrophic factor in motoneurons , 2005, The Journal of Steroid Biochemistry and Molecular Biology.
[126] D. Stein,et al. The neurosteroids progesterone and allopregnanolone reduce cell death, gliosis, and functional deficits after traumatic brain injury in rats. , 2005, Journal of neurotrauma.
[127] D. Stein,et al. Allopregnanolone and progesterone decrease cell death and cognitive deficits after a contusion of the rat pre-frontal cortex , 2004, Neuroscience.
[128] M. Schumacher,et al. Progesterone up-regulates neuronal brain-derived neurotrophic factor expression in the injured spinal cord , 2004, Neuroscience.
[129] C. Frye,et al. Progestins in the Hippocampus of Female Rats Have Antiseizure Effects in a Pentylenetetrazole Seizure Model , 2004, Epilepsia.
[130] P. Hurn,et al. Effects of Combined Estrogen and Progesterone on Brain Infarction in Reproductively Senescent Female Rats , 2004, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[131] H. Bramlett,et al. The effects of early post-traumatic hyperthermia in female and ovariectomized rats. , 2004, Journal of neurotrauma.
[132] M. Schumacher,et al. Progesterone treatment reduces NADPH-diaphorase/nitric oxide synthase in Wobbler mouse motoneuron disease , 2004, Brain Research.
[133] C. Gibson,et al. Progesterone Enhances Functional Recovery after Middle Cerebral Artery Occlusion in Male Mice , 2004, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[134] M. Rogawski,et al. Allopregnanolone Analogs That Positively Modulate GABAA Receptors Protect against Partial Seizures Induced by 6‐Hz Electrical Stimulation in Mice , 2004, Epilepsia.
[135] M. Rogawski,et al. Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice , 2004, Journal of Pharmacology and Experimental Therapeutics.
[136] D. Stein,et al. Effects of progesterone on the inflammatory response to brain injury in the rat , 2004, Brain Research.
[137] R. Zafonte,et al. Evaluation of estrous cycle stage and gender on behavioral outcome after experimental traumatic brain injury , 2004, Brain Research.
[138] M. Schumacher,et al. Systemic progesterone administration results in a partial reversal of the age‐associated decline in CNS remyelination following toxin‐induced demyelination in male rats , 2004, Neuropathology and applied neurobiology.
[139] W. Burnham,et al. The Anticonvulsant Effects of Progesterone and 5α‐dihydroprogesterone on Amygdala‐kindled Seizures in Rats , 2003, Epilepsia.
[140] M. Schumacher,et al. Effects of injury and progesterone treatment on progesterone receptor and progesterone binding protein 25‐Dx expression in the rat spinal cord , 2003, Journal of neurochemistry.
[141] L. Garcia-Segura,et al. Progesterone and its derivatives dihydroprogesterone and tetrahydroprogesterone reduce myelin fiber morphological abnormalities and myelin fiber loss in the sciatic nerve of aged rats , 2003, Neurobiology of Aging.
[142] D. Stein,et al. Behavioral effects and anatomic correlates after brain injury: a progesterone dose–response study , 2003, Pharmacology Biochemistry and Behavior.
[143] G. Fiskum,et al. Ovarian steroid modulation of seizure severity and hippocampal cell death after kainic acid treatment , 2003, Experimental Neurology.
[144] M. Schumacher,et al. Progesterone Neuroprotection in the Wobbler Mouse, a Genetic Model of Spinal Cord Motor Neuron Disease , 2002, Neurobiology of Disease.
[145] M. Schumacher,et al. Basis of progesterone protection in spinal cord neurodegeneration , 2002, The Journal of Steroid Biochemistry and Molecular Biology.
[146] D. Stein,et al. Progesterone Protects against Necrotic Damage and Behavioral Abnormalities Caused by Traumatic Brain Injury , 2002, Experimental Neurology.
[147] P. Hurn,et al. Progesterone Administration during Reperfusion, but not Preischemia Alone, Reduces Injury in Ovariectomized Rats , 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[148] F. Erol,et al. Medroxyprogesterone Acetate, Enoxaparin and Pentoxyfylline Cause Alterations in Lipid Peroxidation, Paraoxonase (PON1) Activities and Homocysteine Levels in the Acute Oxidative Stress in an Experimental Model of Spinal Cord Injury , 2002, Acta Neurochirurgica.
[149] A. Walf,et al. Progesterone Reduces Pentylenetetrazol‐Induced Ictal Activity of Wild‐Type Mice But Not Those Deficient in Type I 5α‐Reductase , 2002, Epilepsia.
[150] M. Schumacher,et al. Cellular basis for progesterone neuroprotection in the injured spinal cord. , 2002, Journal of neurotrauma.
[151] H. Bramlett,et al. Neuropathological protection after traumatic brain injury in intact female rats versus males or ovariectomized females. , 2001, Journal of neurotrauma.
[152] D. Wright,et al. Serum progesterone levels correlate with decreased cerebral edema after traumatic brain injury in male rats. , 2001, Journal of neurotrauma.
[153] C. Frye,et al. 3α,5α-THP in the raphe magnus attenuates PTZ-induced myoclonic seizures , 2001, Brain Research.
[154] T. Di Paolo,et al. Neuroprotective properties of 17β‐estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice , 2001, Synapse.
[155] M. Rogawski,et al. Enhanced Anticonvulsant Activity of Neuroactive Steroids in a Rat Model of Catamenial Epilepsy , 2001, Epilepsia.
[156] D. Stein,et al. Does endogenous progesterone promote recovery of chronic sensorimotor deficits following contusion to the forelimb representation of the sensorimotor cortex? , 2000, Behavioural Brain Research.
[157] C. Frye,et al. Infusion of 3α,5α-THP to the pontine reticular formation attenuates PTZ-induced seizures , 2000, Brain Research.
[158] H. Sienkiewicz-Jarosz,et al. The effects of neurosteroids on picrotoxin-, bicuculline- and NMDA-induced seizures, and a hypnotic effect of ethanol , 2000, Pharmacology Biochemistry and Behavior.
[159] M. Schumacher,et al. Modulation of NADPH-diaphorase and glial fibrillary acidic protein by progesterone in astrocytes from normal and injured rat spinal cord , 2000, The Journal of Steroid Biochemistry and Molecular Biology.
[160] R. Traystman,et al. Progesterone exacerbates striatal stroke injury in progesterone-deficient female animals , 2000, Stroke.
[161] S. Sakaki,et al. Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia. , 2000, Journal of neurosurgery.
[162] C. Frye,et al. Anti-seizure effects of progesterone and 3α,5α-THP in kainic acid and perforant pathway models of epilepsy , 2000, Psychoneuroendocrinology.
[163] T. Di Paolo,et al. Ovarian steroids and raloxifene prevent MPTP‐induced dopamine depletion in mice , 2000, Neuroreport.
[164] M. Chopp,et al. Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat , 1999, Journal of the Neurological Sciences.
[165] Stroke Therapy Academic Industry Roundtable. Recommendations for standards regarding preclinical neuroprotective and restorative drug development. , 1999, Stroke.
[166] M. Chopp,et al. Progesterone is neuroprotective after acute experimental spinal cord trauma in rats. , 1999, Spine.
[167] P. Stanton,et al. Region-specific modulation of limbic seizure susceptibility by ovarian steroids , 1999, Brain Research.
[168] L. Garcia-Segura,et al. Dehydroepiandrosterone, pregnenolone and sexsteroids down-regulate reactive astroglia in the male ratbrain after a penetrating brain injury , 1999, International Journal of Developmental Neuroscience.
[169] M. Rogawski,et al. Finasteride, a 5alpha-reductase inhibitor, blocks the anticonvulsant activity of progesterone in mice. , 1999, The Journal of pharmacology and experimental therapeutics.
[170] C. Frye,et al. Cyclic Withdrawal From Endogenous and Exogenous Progesterone Increases Kainic Acid and Perforant Pathway Induced Seizures , 1999, Pharmacology Biochemistry and Behavior.
[171] J. Horton,et al. Progesterone facilitates the acquisition of avoidance learning and protects against subcortical neuronal death following prefrontal cortex ablation in the rat , 1998, Behavioural Brain Research.
[172] M. Pourgholami,et al. Evaluation of the anticonvulsant profile of progesterone in male amygdala-kindled rats , 1998, Epilepsy Research.
[173] D. Stein,et al. Progesterone protects against lipid peroxidation following traumatic brain injury in rats. , 1997, Molecular and chemical neuropathology.
[174] M. Rogawski,et al. Neuroactive steroids protect against pilocarpine- and kainic acid-induced limbic seizures and status epilepticus in mice , 1996, Neuropharmacology.
[175] Michael Chopp,et al. Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats , 1996, Brain Research.
[176] D. Stein,et al. Progesterone Rapidly Decreases Brain Edema: Treatment Delayed up to 24 Hours Is Still Effective , 1996, Experimental Neurology.
[177] M. Moskowitz,et al. GABAA‐receptor‐mediated effects of progesterone, its ring‐A‐ reduced metabolites and synthetic neuroactive steroids on neurogenic oedema in the rat meninges , 1996, British journal of pharmacology.
[178] M. Schumacher,et al. Progesterone synthesis and myelin formation by Schwann cells. , 1995, Science.
[179] C. Frye. The neurosteroid 3α,5α-THP has antiseizure and possible neuroprotective effects in an animal model of epilepsy , 1995, Brain Research.
[180] A. Herzog. Progesterone therapy in women with complex partial and secondary generalized seizures , 1995, Neurology.
[181] D. Stein,et al. Blood-brain barrier breakdown and edema formation following frontal cortical contusion: does hormonal status play a role? , 1995, Journal of neurotrauma.
[182] D. Stein,et al. Progesterone Facilitates Cognitive Recovery and Reduces Secondary Neuronal Loss Caused by Cortical Contusion Injury in Male Rats , 1994, Experimental Neurology.
[183] E. Soriano,et al. Gonadal hormones down-regulate reactive gliosis and astrocyte proliferation after a penetrating brain injury , 1993, Brain Research.
[184] Donald G. Stein,et al. Gender-specific impairment on Morris water maze task after entorhinal cortex lesion , 1993, Behavioural Brain Research.
[185] D. Stein,et al. Gender influences outcome of brain injury: progesterone plays a protective role , 1993, Brain Research.
[186] E. Taubøll,et al. The effect of progesterone and its metabolite 5α-pregnan-3α-ol-20-one on focal epileptic seizures in the cat's visual cortex in vivo , 1993, Epilepsy Research.
[187] A. Betz,et al. Effect of steroids on edema and sodium uptake of the brain during focal ischemia in rats. , 1990, Stroke.
[188] M. Bolger,et al. Anticonvulsant profile of the progesterone metabolite 5α-pregnan-3α-ol-20-one , 1989 .
[189] W. Yu. Survival of motoneurons following axotomy is enhanced by lactation or by progesterone treatment , 1989, Brain Research.
[190] D. Stein,et al. Hormonal state affects recovery from frontal cortex lesions in adult female rats. , 1987, Behavioral and neural biology.
[191] F. Nicoletti,et al. Comparative Effects of Estradiol Benzoate, the Antiestrogen Clomiphene Citrate, and the Progestin Medroxyprogesterone Acetate on Kainic Acid‐Induced Seizures in Male and Female Rats , 1985, Epilepsia.
[192] J. Cramer,et al. Treatment of seizures with medroxyprogesterone acetate , 1984, Neurology.
[193] K. Barlow. Traumatic brain injury. , 2013, Handbook of clinical neurology.
[194] N. Shahrokhi,et al. Time- and dose-dependent neuroprotective effects of sex steroid hormones on inflammatory cytokines after a traumatic brain injury. , 2013, Journal of neurotrauma.
[195] T. Bäckström,et al. Chronic allopregnanolone treatment accelerates Alzheimer's disease development in AβPP(Swe)PSEN1(ΔE9) mice. , 2012, Journal of Alzheimer's disease : JAD.
[196] G. Moralí,et al. Cytoarchitectural characteristics of hippocampal CA1 pyramidal neurons of rats, four months after global cerebral ischemia and progesterone treatment. , 2012, Restorative neurology and neuroscience.
[197] M. Cekic,et al. Progesterone treatment alters neurotrophin/proneurotrophin balance and receptor expression in rats with traumatic brain injury. , 2012, Restorative neurology and neuroscience.
[198] D. Stein,et al. Improved behavioral outcomes after progesterone administration in aged male rats with traumatic brain injury. , 2011, Restorative neurology and neuroscience.
[199] M. F. Coronel,et al. Progesterone prevents allodynia after experimental spinal cord injury. , 2011, The journal of pain : official journal of the American Pain Society.
[200] C. Espinosa-Garcia,et al. Neuroprotective effects of progesterone and allopregnanolone on long-term cognitive outcome after global cerebral ischemia. , 2011, Restorative neurology and neuroscience.
[201] R. Keep,et al. Effects of progesterone and testosterone on ICH-induced brain injury in rats. , 2011, Acta neurochirurgica. Supplement.
[202] R. Chin. Progesterone Promotes the Survival of Newborn Neurons in the Dentate Gyrus of Adult Male Mice , 2010 .
[203] M. Schumacher,et al. Stage Dependent Effects of Progesterone on Motoneurons and Glial Cells of Wobbler Mouse Spinal Cord Degeneration , 2009, Cellular and Molecular Neurobiology.
[204] V. Ozacmak,et al. The effects of 17beta estradiol, 17alpha estradiol and progesterone on oxidative stress biomarkers in ovariectomized female rat brain subjected to global cerebral ischemia. , 2009, Physiological research.
[205] D. Stein,et al. Cortical activation during finger tracking vs. ankle tracking in healthy subjects , 2009 .
[206] D. Stein,et al. Progesterone inhibits ischemic brain injury in a rat model of permanent middle cerebral artery occlusion. , 2007, Restorative neurology and neuroscience.
[207] M. Schumacher,et al. Progesterone treatment of spinal cord injury , 2007, Journal of Molecular Neuroscience.
[208] D. Stein,et al. Allopregnanolone, a progesterone metabolite, enhances behavioral recovery and decreases neuronal loss after traumatic brain injury. , 2004, Restorative neurology and neuroscience.
[209] G. Moralí,et al. Neuroprotective effects of progesterone on damage elicited by acute global cerebral ischemia in neurons of the caudate nucleus. , 2002, Archives of medical research.
[210] D. Stein,et al. Effects of the duration of progesterone treatment on the resolution of cerebral edema induced by cortical contusions in rats. , 2001, Restorative neurology and neuroscience.
[211] P. Liao,et al. Estrogen and progesterone distinctively modulate methamphetamine-induced dopamine and serotonin depletions in C57BL/6J mice , 2000, Journal of Neural Transmission.
[212] R. Traystman,et al. Neuroprotective effects of female gonadal steroids in reproductively senescent female rats. , 2000, Stroke.
[213] L. Goldstein,et al. Age but not sex affects motor recovery after unilateral sensorimotor cortex suction-ablation in the rat. , 1999, Restorative neurology and neuroscience.
[214] G. Moralí,et al. Progesterone: protective effects on the cat hippocampal neuronal damage due to acute global cerebral ischemia. , 1998, Archives of medical research.
[215] D. Stein,et al. Progesterone treatment attenuates brain edema following contusion injury in male and female rats. , 1992, Restorative neurology and neuroscience.
[216] A. Betz,et al. Effect of steroid therapy on ischaemic brain oedema and blood to brain sodium transport. , 1990, Acta neurochirurgica. Supplementum.
[217] M. Bolger,et al. Anticonvulsant profile of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one. , 1989, European journal of pharmacology.