Ultrasound propagation model for attenuation reduction and cardiac contrast perfusion visualization

A mathematical model of ultrasound signal propagation through cardiac muscle has been designed and applied to myocardial contrast images of the heart. The fundamental frequency component of the propagating signals serves in the model for attenuation estimation. These estimates are used to reduce the effect of tissue attenuation on the harmonic component of the received signals, which are used for ultrasound contrast perfusion imaging. A new parameter is introduced for automatic mapping and visualization of perfused and nonperfused myocardium and cardiac cavity in contrast echocardiographic images.

[1]  K J Parker,et al.  Contrast agents in diagnostic ultrasound. , 1989, Ultrasound in medicine & biology.

[2]  H. Dittrich,et al.  Myocardial contrast echocardiography in experimental coronary artery occlusion with a new intravenously administered contrast agent. , 1995, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[3]  Peter N. Burns,et al.  Perfusion imaging with pulse inversion Doppler and microbubble contrast agents: in vivo studies of the myocardium , 1998, 1998 IEEE Ultrasonics Symposium. Proceedings (Cat. No. 98CH36102).

[4]  P. Burns Harmonic imaging with ultrasound contrast agents. , 1996, Clinical radiology.

[5]  J Sklenar,et al.  Potential advantage of flash echocardiography for digital subtraction of B-mode images acquired during myocardial contrast echocardiography. , 1999, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[6]  Francis A. Duck,et al.  Physical properties of tissue : a comprehensive reference book , 1990 .

[7]  T. Porter,et al.  Detection of myocardial perfusion in multiple echocardiographic windows with one intravenous injection of microbubbles using transient response second harmonic imaging. , 1997, Journal of the American College of Cardiology.

[8]  P. Dayton,et al.  Mechanisms of contrast agent destruction , 2001, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[9]  Malcolm J. Crocker,et al.  Encyclopedia of Acoustics , 1998 .